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Select item 110289101.

FOXO3, estrogen receptor alpha, and androgen receptor impact tumor growth rate and infiltration of dendritic cell subsets differentially between male and female mice

Matthew G. Thompson, Daniel S. Peiffer, Michelle Larson, Flor Navarro, Stephanie K. Watkins

Cancer Immunol Immunother. 2017 May; 66(5): 615–625. Published online 2017 Feb 22. doi: 10.1007/s00262-017-1972-4

PMCID:: PMC11028910

Abstract Article PDF–1.6M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108055033.

Microglial FoxO3a deficiency ameliorates ferroptosis‐induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase‐1

Rikang Wang, Zhi Liang, Xiaoyan Xue, Hua Mei, Lianru Ji, Bocheng Wang, Wenjin Chen, Chao Gao, Shun Yuan, Tao Wu, Hui Qi, Suifa Hu, Li Yi, Yonggui Song, Rifang Liao, Baodong Chen

J Cell Mol Med. 2024 Jan; 28(1): e18007. Published online 2023 Oct 27. doi: 10.1111/jcmm.18007

PMCID:: PMC10805503

Abstract Article PDF–30M

Select item 105630864.

FoxO3 Modulates Circadian Rhythms in Neural Stem Cells

Swip Draijer, Raissa Timmerman, Jesse Pannekeet, Alexandra van Harten, Elham Aida Farshadi, Julius Kemmer, Demy van Gilst, Inês Chaves, Marco F. M. Hoekman

Int J Mol Sci. 2023 Sep; 24(17): 13662. Published online 2023 Sep 4. doi: 10.3390/ijms241713662

PMCID:: PMC10563086

Abstract Article PDF–3.8M

Select item 105298795.

Autophagy collaborates with apoptosis pathways to control oligodendrocyte number

Tingxin Zhang, Aksheev Bhambri, Yihe Zhang, Daniela Barbosa, Han-Gyu Bae, Jumin Xue, Sabeen Wazir, Sara B. Mulinyawe, Jun Hee Kim, Lu O. Sun

Cell Rep. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112943. Published online 2023 Aug 6. doi: 10.1016/j.celrep.2023.112943

PMCID:: PMC10529879

Abstract Article PDF–3.5M

Select item 104866496.

Foxo3 Knockdown Mediates Decline of Myod1 and Myog Reducing Myoblast Conversion to Myotubes

Benjamin Gellhaus, Kai O. Böker, Marlene Gsaenger, Eyck Rodenwaldt, Marc A. Hüser, Arndt F. Schilling, Dominik Saul

Cells. 2023 Sep; 12(17): 2167. Published online 2023 Aug 29. doi: 10.3390/cells12172167

PMCID:: PMC10486649

Abstract Article PDF–2.5M

Select item 104107567.

MBTD1 preserves adult hematopoietic stem cell pool size and function

Keiyo Takubo, Phyo Wai Htun, Takeshi Ueda, Yasuyuki Sera, Masayuki Iwasaki, Miho Koizumi, Kohei Shiroshita, Hiroshi Kobayashi, Miho Haraguchi, Shintaro Watanuki, Zen-ichiro Honda, Norimasa Yamasaki, Ayako Nakamura-Ishizu, Fumio Arai, Noboru Motoyama, Tomohisa Hatta, Tohru Natsume, Toshio Suda, Hiroaki Honda

Proc Natl Acad Sci U S A. 2023 Aug 8; 120(32): e2206860120. Published online 2023 Jul 31. doi: 10.1073/pnas.2206860120

PMCID:: PMC10410756

Abstract Article PDF–2.2M

Select item 104107178.

Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve

Camilla H. K. Hughes, Olivia E. Smith, Marie-Charlotte Meinsohn, Mylène Brunelle, Nicolas Gévry, Bruce D. Murphy

Proc Natl Acad Sci U S A. 2023 Aug 8; 120(32): e2220849120. Published online 2023 Jul 26. doi: 10.1073/pnas.2220849120

PMCID:: PMC10410717

Abstract Article PDF–3.9M

Select item 103187949.

Downregulation of circ-Foxo3 in breast cancer stem-like cells

Mohammad Kamalabadi-Farahani, Amir Atashi, Mohammad Masoud Eslami

BMC Res Notes. 2023; 16: 132. Published online 2023 Jul 3. doi: 10.1186/s13104-023-06405-z

PMCID:: PMC10318794

Abstract Article PDF–1.0M

Select item 1026276310.

The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma

Jianfang Niu, Taiqiang Yan, Wei Guo, Wei Wang, Tingting Ren, Yi Huang, Zhiqing Zhao, Yiyang Yu, Chenglong Chen, Qingshan Huang, Jingbing Lou, Lei Guo

Autophagy. 2023; 19(6): 1693–1710. Published online 2022 Nov 30. doi: 10.1080/15548627.2022.2150003

PMCID:: PMC10262763

Abstract Article PDF–4.9M

Select item 1025347011.

FOXO3 Deficiency in Neutrophils Drives Colonic Inflammation and Tumorigenesis

Jenisha Ghimire, Rida Iftikhar, Harrison M. Penrose, Patricia Snarski, Emmanuelle Ruiz, Suzana D. Savkovic

Int J Mol Sci. 2023 Jun; 24(11): 9730. Published online 2023 Jun 4. doi: 10.3390/ijms24119730

PMCID:: PMC10253470

Abstract Article PDF–4.8M

Select item 1019282112.

Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest

Bipul R Acharya, Jennifer S Fang, Erin D Jeffery, Nicholas W Chavkin, Gael Genet, Hema Vasavada, Elizabeth A Nelson, Gloria M Sheynkman, Martin J Humphries, Karen K Hirschi

Life Sci Alliance. 2023 Aug; 6(8): e202201685. Published online 2023 May 17. doi: 10.26508/lsa.202201685

PMCID:: PMC10192821

Abstract Article PDF–3.0M

Select item 1005039613.

Mitochondria-derived H₂O₂ triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice

Hua Bai, Cong-Wen Fang, Ying Shi, Song Zhai, An Jiang, Ying-Na Li, Lin Wang, Qi-Ling Liu, Geng-Yao Zhou, Jia-Hao Cao, Jia Li, Xue-Kang Yang, Xu-Jun Qin

Cell Death Dis. 2023 Mar; 14(3): 216. Published online 2023 Mar 28. doi: 10.1038/s41419-023-05744-w

PMCID:: PMC10050396

Abstract Article PDF–5.3M

Select item 998168714.

MYTHO is a novel regulator of skeletal muscle autophagy and integrity

Jean-Philippe Leduc-Gaudet, Anais Franco-Romero, Marina Cefis, Alaa Moamer, Felipe E. Broering, Giulia Milan, Roberta Sartori, Tomer Jordi Chaffer, Maude Dulac, Vincent Marcangeli, Dominique Mayaki, Laurent Huck, Anwar Shams, José A. Morais, Elise Duchesne, Hanns Lochmuller, Marco Sandri, Sabah N. A. Hussain, Gilles Gouspillou

Nat Commun. 2023; 14: 1199. Published online 2023 Mar 2. doi: 10.1038/s41467-023-36817-1

PMCID:: PMC9981687

Abstract Article PDF–13M

Select item 995051515.

Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age

Jorge Lopez-Tello, Amanda N. Sferruzzi-Perri

Front Endocrinol (Lausanne) 2023; 14: 1116770. Published online 2023 Feb 10. doi: 10.3389/fendo.2023.1116770

PMCID:: PMC9950515

Abstract Article PDF–4.2M

Select item 989194016.

Loss of FoxOs in muscle increases strength and mitochondrial function during aging

Christie M. Penniman, Gourav Bhardwaj, Colette J. Nowers, Chandler U. Brown, Taylor L. Junck, Cierra K. Boyer, Jayashree Jena, Jordan D. Fuqua, Vitor A. Lira, Brian T. O'Neill

J Cachexia Sarcopenia Muscle. 2023 Feb; 14(1): 243–259. Published online 2022 Nov 28. doi: 10.1002/jcsm.13124

PMCID:: PMC9891940

Abstract Article PDF–4.8M

Select item 974135917.

FOXO3a Mediates Homologous Recombination Repair (HRR) via Transcriptional Activation of MRE11, BRCA1, BRIP1, and RAD50

Gozde Inci, Madhuri Shende Warkad, Beom-Goo Kang, Na-Kyung Lee, Hong-Won Suh, Soon Sung Lim, Jaebong Kim, Sung-Chan Kim, Jae-Yong Lee

Molecules. 2022 Dec; 27(23): 8623. Published online 2022 Dec 6. doi: 10.3390/molecules27238623

PMCID:: PMC9741359

Abstract Article PDF–3.1M

Select item 964061018.

CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy

Chen Zhao, Xiaodong Li, Guantong Sun, Pengcheng Liu, Keyu Kong, Xuzhuo Chen, Fei Yang, Xiaoqing Wang

Cell Death Dis. 2022 Nov; 13(11): 932. Published online 2022 Nov 7. doi: 10.1038/s41419-022-05390-8

PMCID:: PMC9640610

Abstract Article PDF–6.6M

Select item 947961019.

The FoxO4/DKK3 axis represses IFN-γ expression by Th1 cells and limits antimicrobial immunity

Xiang Chen, Jia Hu, Yunfei Wang, Younghee Lee, Xiaohong Zhao, Huiping Lu, Gengzhen Zhu, Hui Wang, Yu Jiang, Fan Liu, Yongzhen Chen, Byung-Seok Kim, Qinghua Zhou, Xindong Liu, Xiaohu Wang, Seon Hee Chang, Chen Dong

J Clin Invest. 2022 Sep 15; 132(18): e147566. Published online 2022 Sep 15. doi: 10.1172/JCI147566

PMCID:: PMC9479610

Abstract Article PDF–4.0M

Select item 944680020.

Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia

Yating Wang, Stefano Spolitu, John A. Zadroga, Amesh K. Sarecha, Lale Ozcan

Cell Rep. Author manuscript; available in PMC 2022 Sep 6.

Published in final edited form as: Cell Rep. 2022 Aug 23; 40(8): 111259. doi: 10.1016/j.celrep.2022.111259

PMCID:: PMC9446800

Abstract Article PDF–1.2M

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