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Select item 111588831.

Epidermal growth factor receptor intron 1 CA dinucleotide repeat polymorphism and survival of advanced gastric cancer patients treated with cetuximab plus modified FOLFOX6

Sae‐Won Han, Do‐Youn Oh, Seock‐Ah Im, Sook Ryun Park, Keun‐Wook Lee, Hong Suk Song, Nam‐Su Lee, Kyung Hee Lee, In Sil Choi, Moon Hee Lee, Min A Kim, Woo Ho Kim, Yung‐Jue Bang, Tae‐You Kim

Cancer Sci. 2010 Mar; 101(3): 793–799. Published online 2009 Nov 23. doi: 10.1111/j.1349-7006.2009.01447.x

PMCID:: PMC11158883

Abstract Article PDF–174K

Select item 111588402.

BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin

Hyun Jeong Shim, Joo Young Yun, Jun Eul Hwang, Woo Kyun Bae, Sang Hee Cho, Ji Hee Lee, Hee Nam Kim, Min Ho Shin, Sun Seog Kweon, Jae Hyuk Lee, Hyeoung Joon Kim, Ik Joo Chung

Cancer Sci. 2010 May; 101(5): 1247–1254. Published online 2010 Mar 12. doi: 10.1111/j.1349-7006.2010.01514.x

PMCID:: PMC11158840

Abstract Article PDF–215K

Select item 111585783.

One‐carbon metabolism‐related gene polymorphisms and risk of head and neck squamous cell carcinoma: Case–control study

Takeshi Suzuki, Keitaro Matsuo, Yasuhisa Hasegawa, Akio Hiraki, Kenji Wakai, Kaoru Hirose, Toshiko Saito, Shigeki Sato, Ryuzo Ueda, Kazuo Tajima

Cancer Sci. 2007 Sep; 98(9): 1439–1446. Published online 2007 Jun 26. doi: 10.1111/j.1349-7006.2007.00533.x

PMCID:: PMC11158578

Abstract Article PDF–126K

Select item 105658764.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104805355.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 104541596.

Association of Thymidylate Synthase (TS) Gene Polymorphisms with Incidence and Prognosis of Coronary Artery Disease

Jung Oh Kim, Chang Soo Ryu, Jeong Yong Lee, Eun Ju Ko, Yong Hyun Ha, Jung Hoon Sung, Tae Sun Hwang, In Jai Kim, Nam Keun Kim

Int J Mol Sci. 2023 Aug; 24(16): 12591. Published online 2023 Aug 9. doi: 10.3390/ijms241612591

PMCID:: PMC10454159

Abstract Article PDF–758K

Select item 102441717.

TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background

Maria V. Guijarro, Akbar Nawab, Peter Dib, Sandra Burkett, Xiaoping Luo, Michael Feely, Elham Nasri, Robert P. Seifert, Frederic J. Kaye, Maria Zajac-Kaye

Oncogene. 2023; 42(23): 1926–1939. Published online 2023 Apr 27. doi: 10.1038/s41388-023-02694-7

PMCID:: PMC10244171

Abstract Article PDF–4.5M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 98160599.

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Dongbao Li, Yuhong Wang, Chao Dong, Tao Chen, Anqi Dong, Jiayu Ren, Weikang Li, Gege Shu, Jiaoyang Yang, Wenhao Shen, Lei Qin, Lin Hu, Jin Zhou

Oncogene. 2023; 42(2): 83–98. Published online 2022 Nov 12. doi: 10.1038/s41388-022-02537-x

PMCID:: PMC9816059

Abstract Article PDF–7.6M

Select item 981030710.

Evaluation of TS and ENOSF1 Variants as a Biomarker in Response to Neoadjuvant Chemotherapy based on 5FU in Gastric Cancer Patients

Khadijeh Arjmandi, Fereshteh Ameli, Iman Salahshourifar, Mohsen Esfandbod, Shiva Irani

Asian Pac J Cancer Prev. 2022 Sep; 23(9): 2983–2989. doi: 10.31557/APJCP.2022.23.9.2983

PMCID:: PMC9810307

Abstract Article PDF–473K

Select item 979335911.

SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis

Saisai Guo, Xiaobo Lei, Yan Chang, Jianyuan Zhao, Jing Wang, Xiaojing Dong, Qian Liu, Zixiong Zhang, Lidan Wang, Dongrong Yi, Ling Ma, Quanjie Li, Yongxin Zhang, Jiwei Ding, Chen Liang, Xiaoyu Li, Fei Guo, Jianwei Wang, Shan Cen

Signal Transduct Target Ther. 2022; 7: 400. Published online 2022 Dec 27. doi: 10.1038/s41392-022-01239-w

PMCID:: PMC9793359

Abstract Article PDF–3.7M

Select item 976969812.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 947545313.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 938838914.

Germline thymidylate synthase deficiency impacts nucleotide metabolism and causes dyskeratosis congenita

Hemanth Tummala, Amanda Walne, Roberto Buccafusca, Jenna Alnajar, Anita Szabo, Peter Robinson, Allyn McConkie-Rosell, Meredith Wilson, Suzanne Crowley, Veronica Kinsler, Anna-Maria Ewins, Pradeepa M. Madapura, Manthan Patel, Nikolas Pontikos, Veryan Codd, Tom Vulliamy, Inderjeet Dokal

Am J Hum Genet. 2022 Aug 4; 109(8): 1472–1483. Published online 2022 Aug 5. doi: 10.1016/j.ajhg.2022.06.014

Correction in:: Am J Hum Genet. 2024 Jul 11; 111(7): 1494.

PMCID:: PMC9388389

Abstract Article PDF–2.3M

Select item 933831315.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 927928516.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 910630317.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 895155618.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 889702219.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 885704920.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

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Postmortem temporal cortex from Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort: astrocytes
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