PMC Links for GEO Profiles (Select 61681634) - PMC

Farah Lizotte, Stéphanie Robillard, Nicolas Lavoie, Marina Rousseau, Benoit Denhez, Julie Moreau, Sarah Higgins, Robert Sabbagh, Anne-Marie Côté, Pedro Geraldes

Kidney360. 2022 Oct 27; 3(10): 1710–1719. Published online 2022 Aug 31. doi: 10.34067/KID.0002152022

PMCID:: PMC9717659

Abstract Article PDF–1.0M

Select item 96239794.

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality

Arti T. Navare, Fred D. Mast, Jean Paul Olivier, Thierry Bertomeu, Maxwell L. Neal, Lindsay N. Carpp, Alexis Kaushansky, Jasmin Coulombe-Huntington, Mike Tyers, John D. Aitchison

J Cell Biol. 2022 Nov 7; 221(11): e202011050. Published online 2022 Oct 28. doi: 10.1083/jcb.202011050

PMCID:: PMC9623979

Abstract Article PDF–3.7M

Select item 95882325.

SHP-1 knockdown suppresses mitochondrial biogenesis and aggravates mitochondria-dependent apoptosis induced by all trans retinal through the STING/AMPK pathways

Xiaonan Zhuang, Jun Ma, Gezhi Xu, Zhongcui Sun

Mol Med. 2022; 28: 125. Published online 2022 Oct 22. doi: 10.1186/s10020-022-00554-w

PMCID:: PMC9588232

Abstract Article PDF–2.9M

Select item 95312956.

SHP‐1 dephosphorylates histone H2B to facilitate its ubiquitination during transcription

Prajakta Tathe, K V S Rammohan Chowdary, Krushna Chandra Murmu, Punit Prasad, Subbareddy Maddika

EMBO J. 2022 Oct; 41(19): e109720. Published online 2022 Aug 8. doi: 10.15252/embj.2021109720

PMCID:: PMC9531295

Abstract Article PDF–2.7M

Select item 94748257.

A LILRB1 variant with a decreased ability to phosphorylate SHP-1 leads to autoimmune diseases

Thivaratana Sinthuwiwat, Supranee Buranapraditkun, Wuttichart Kamolvisit, Siraprapa Tongkobpetch, Wanna Chetruengchai, Chalurmpon Srichomthong, Adjima Assawapitaksakul, Chureerat Phokaew, Patipark Kueanjinda, Tanapat Palaga, Tadech Boonpiyathad, Kanya Suphapeetiporn, Nattiya Hirankarn, Vorasuk Shotelersuk

Sci Rep. 2022; 12: 15420. Published online 2022 Sep 14. doi: 10.1038/s41598-022-19334-x

PMCID:: PMC9474825

Abstract Article PDF–2.6M

Select item 94379288.

The tyrosine phosphatase SHP-1 promotes T cell adhesion by activating the adaptor protein CrkII in the immunological synapse

Inbar Azoulay-Alfaguter, Marianne Strazza, Michael Peled, Hila K. Novak, James Muller, Michael L. Dustin, Adam Mor

Sci Signal. Author manuscript; available in PMC 2022 Sep 2.

Published in final edited form as: Sci Signal. 2017 Aug 8; 10(491): eaal2880. Published online 2017 Aug 8. doi: 10.1126/scisignal.aal2880

PMCID:: PMC9437928

Abstract Article PDF–1.8M

Select item 92792859.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 876907210.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 875161311.

METTL14 benefits the mesenchymal stem cells in patients with steroid-associated osteonecrosis of the femoral head by regulating the m6A level of PTPN6

Cheng Cheng, Haoping Zhang, Jia Zheng, Yi Jin, Donghui Wang, Zhipeng Dai

Aging (Albany NY) 2021 Dec 31; 13(24): 25903–25919. Published online 2021 Dec 15. doi: 10.18632/aging.203778

PMCID:: PMC8751613

Abstract Article PDF–1.8M

Select item 849671112.

Vitamin D3-VDR-PTPN6 axis mediated autophagy contributes to the inhibition of macrophage foam cell formation

Sumit Kumar, Ravikanth Nanduri, Ella Bhagyaraj, Rashi Kalra, Nancy Ahuja, Anuja P. Chacko, Drishti Tiwari, Kanupriya Sethi, Ankita Saini, Vemika Chandra, Monika Jain, Shalini Gupta, Deepak Bhatt, Pawan Gupta

Autophagy. 2021; 17(9): 2273–2289. Published online 2020 Sep 24. doi: 10.1080/15548627.2020.1822088

PMCID:: PMC8496711

Abstract Article PDF–11M

Select item 844752313.

Circular RNA-0007059 protects cell viability and reduces inflammation in a nephritis cell model by inhibiting microRNA-1278/SHP-1/STAT3 signaling

Peng-Wei Guo, Hai-Ting Huang, Jing Ma, Yao Zuo, Dan Huang, Lin-Lin He, Zi-Ming Wan, Cheng Chen, Fa-Fen Yang, Yan-Wu You

Mol Med. 2021; 27: 113. Published online 2021 Sep 17. doi: 10.1186/s10020-021-00372-6

PMCID:: PMC8447523

Abstract Article PDF–7.2M

Select item 834298714.

TRIM31 facilitates K27-linked polyubiquitination of SYK to regulate antifungal immunity

Xueer Wang, Honghai Zhang, Zhugui Shao, Wanxin Zhuang, Chao Sui, Feng Liu, Xiaorong Chen, Jinxiu Hou, Lingli Kong, Hansen Liu, Yi Zheng, Bingyu Liu, Tian Chen, Lei Zhang, Xinming Jia, Chengjiang Gao

Signal Transduct Target Ther. 2021; 6: 298. Published online 2021 Aug 6. doi: 10.1038/s41392-021-00711-3

PMCID:: PMC8342987

Abstract Article PDF–6.2M

Select item 832170115.

CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP

Kanako Nishiyama, Masashi Maekawa, Tomoya Nakagita, Jun Nakayama, Takeshi Kiyoi, Mami Chosei, Akari Murakami, Yoshiaki Kamei, Hiroyuki Takeda, Yasutsugu Takada, Shigeki Higashiyama

Life Sci Alliance. 2021 Sep; 4(9): e202101095. Published online 2021 Jun 29. doi: 10.26508/lsa.202101095

PMCID:: PMC8321701

Abstract Article PDF–4.8M

Select item 817676316.

The phosphatase Shp1 interacts with and dephosphorylates cortactin to inhibit invadopodia function

Alessia Varone, Chiara Amoruso, Marcello Monti, Manpreet Patheja, Adelaide Greco, Luigi Auletta, Antonella Zannetti, Daniela Corda

Cell Commun Signal. 2021; 19: 64. Published online 2021 Jun 4. doi: 10.1186/s12964-021-00747-6

PMCID:: PMC8176763

Abstract Article PDF–2.8M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 798323718.

The role of Src homology region 2 domain-containing phosphatase-1 hypermethylation in the classification of patients with myelodysplastic syndromes and its association with signal transducer and activator of transcription 3 phosphorylation in skm-1 cells

Ying Han, Jin Zhang, Yanbin Pang, Yamei Wang, Xinying Zhang, Hongze Zhang

J Int Med Res. 2021 Mar; 49(3): 0300060521999550. Published online 2021 Mar 18. doi: 10.1177/0300060521999550

PMCID:: PMC7983237

Abstract Article PDF–453K

Select item 755071819.

Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity

Darienne R. Myers, Clare L. Abram, David Wildes, Amira Belwafa, Alia M. N. Welsh, Christopher J. Schulze, Tiffany J. Choy, Tram Nguyen, Neil Omaque, Yongmei Hu, Mallika Singh, Rich Hansen, Mark A. Goldsmith, Elsa Quintana, Jacqueline A. M. Smith, Clifford A. Lowell

Front Immunol. 2020; 11: 576310. Published online 2020 Sep 29. doi: 10.3389/fimmu.2020.576310

PMCID:: PMC7550718

Abstract Article PDF–2.4M

Select item 740483820.

SHP‐1 suppresses the antiviral innate immune response by targeting TRAF3

Doudou Hao, Yu Wang, Liuyan Li, Gui Qian, Jing Liu, Manman Li, Yihua Zhang, Ruixue Zhou, Dapeng Yan

FASEB J. 2020 Sep; 34(9): 12392–12405. Published online 2020 Jul 23. doi: 10.1096/fj.202000600RR

PMCID:: PMC7404838

Abstract Article PDF–1.5M

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