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Select item 112971571.

Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development

Hao Zeng, Xue Yang, Kai Liao, Xin Zuo, Lihong Liang, Dalian He, Rong Ju, Bowen Wang, Jin Yuan

Exp Mol Med. 2024 Jul; 56(7): 1655–1666. Published online 2024 Jul 2. doi: 10.1038/s12276-024-01269-0

PMCID:: PMC11297157

Abstract Article PDF–3.3M

Select item 111617562.

Phosphorylation of DNA-binding domains of CLOCK–BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells

Yuta Otobe, Eui Min Jeong, Shunsuke Ito, Yuta Shinohara, Nobuhiro Kurabayashi, Atsu Aiba, Yoshitaka Fukada, Jae Kyoung Kim, Hikari Yoshitane

Proc Natl Acad Sci U S A. 2024 Jun 4; 121(23): e2316858121. Published online 2024 May 28. doi: 10.1073/pnas.2316858121

PMCID:: PMC11161756

Abstract Article PDF–4.4M

Select item 110720083.

Artificial induction of circadian rhythm by combining exogenous BMAL1 expression and polycomb repressive complex 2 inhibition in human induced pluripotent stem cells

Hitomi Kaneko, Taku Kaitsuka, Kazuhito Tomizawa

Cell Mol Life Sci. 2023 Aug; 80(8): 200. Published online 2023 Jul 8. doi: 10.1007/s00018-023-04847-z

PMCID:: PMC11072008

Abstract Article PDF–2.5M

Select item 110694894.

Targeting BMAL1 reverses drug resistance of acute myeloid leukemia cells and promotes ferroptosis through HMGB1-GPX4 signaling pathway

Hong Zheng, Ting Wu, Zhi Lin, Dan Wang, Jing Zhang, Ting Zeng, Leping Liu, Jie Shen, Mingyi Zhao, Jia-Da Li, Minghua Yang

J Cancer Res Clin Oncol. 2024; 150(5): 231. Published online 2024 May 4. doi: 10.1007/s00432-024-05753-y

PMCID:: PMC11069489

Abstract Article PDF–12M

Select item 104782285.

Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling

Deze Zhao, Yeping Dong, Minghao Duan, Dan He, Qun Xie, Wei Peng, Weifang Cui, Junjie Jiang, Yuanda Cheng, Heng Zhang, Faqing Tang, Chunfang Zhang, Yang Gao, Chaojun Duan

J Exp Clin Cancer Res. 2023; 42: 229. Published online 2023 Sep 4. doi: 10.1186/s13046-023-02791-1

PMCID:: PMC10478228

Abstract Article PDF–9.1M

Select item 103823066.

Association of BMAL1 clock gene polymorphisms with fasting glucose in children

Yi-De Yang, Yuan Zeng, Jian Li, Jun-Hua Zhou, Quan-Yuan He, Chan-Juan Zheng, Christoph Reichetzeder, Bernhard K. Krämer, Berthold Hocher

Pediatr Res. 2023; 94(2): 653–659. Published online 2023 Feb 2. doi: 10.1038/s41390-023-02467-8

PMCID:: PMC10382306

Abstract Article PDF–908K

Select item 102731167.

Is BMAL1 Just One Song Impacting the Circadian Dance of Lung Injury?

Nancy H. Stewart, Isaac Kirubakaran Sundar

Am J Respir Crit Care Med. 2023 Jun 15; 207(12): 1642. Published online 2023 Feb 2. doi: 10.1164/rccm.202212-2311LE

PMCID:: PMC10273116

Article PDF–494K

Select item 99262578.

Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle

Meng Qu, Guoxin Zhang, Han Qu, Alexander Vu, Raymond Wu, Hidekazu Tsukamoto, Zhenyu Jia, Wendong Huang, Heinz-Josef Lenz, Jeremy N. Rich, Steve A. Kay

Proc Natl Acad Sci U S A. 2023 Jan 10; 120(2): e2214829120. Published online 2023 Jan 3. doi: 10.1073/pnas.2214829120

PMCID:: PMC9926257

Abstract Article PDF–730K

Select item 98683889.

Bmal1 and Gut-lung axis in SARS-CoV-2 infection: New insight into the effects of melatonin on COVID-19 patients?

Mohammad Rafi Khezri, Reza Varzandeh, Morteza Ghasemnejad-Berenji

Biomed Pharmacother. 2023 Aug; 164: 114291. Published online 2023 Jan 23. doi: 10.1016/j.biopha.2023.114291

PMCID:: PMC9868388

Abstract Article PDF–844K

Select item 986591210.

The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship

Masanori Ono, Hitoshi Ando, Takiko Daikoku, Tomoko Fujiwara, Michihiro Mieda, Yasunari Mizumoto, Takashi Iizuka, Kyosuke Kagami, Takashi Hosono, Satoshi Nomura, Natsumi Toyoda, Naomi Sekizuka-Kagami, Yoshiko Maida, Naoaki Kuji, Hirotaka Nishi, Hiroshi Fujiwara

Int J Mol Sci. 2023 Jan; 24(2): 1545. Published online 2023 Jan 12. doi: 10.3390/ijms24021545

PMCID:: PMC9865912

Abstract Article PDF–1011K

Select item 984759511.

Melatonin upregulates BMAL1 to attenuate chronic sleep deprivation‐related cognitive impairment by alleviating oxidative stress

Yujie Hu, Jierong Yin, Guoshuai Yang

Brain Behav. 2023 Jan; 13(1): e2836. Published online 2022 Dec 23. doi: 10.1002/brb3.2836

PMCID:: PMC9847595

Abstract Article PDF–974K

Select item 973225812.

BMAL1/FOXA2-induced rhythmic fluctuations in IL-6 contribute to nocturnal asthma attacks

Lingling Tang, Li Liu, Xianhong Sun, Po Hu, Hui Zhang, Bohan Wang, Xiaona Zhang, Jinjin Jiang, Xia Zhao, Xiaolu Shi

Front Immunol. 2022; 13: 947067. Published online 2022 Nov 25. doi: 10.3389/fimmu.2022.947067

PMCID:: PMC9732258

Abstract Article PDF–16M

Select item 968280513.

Circadian clock gene Clock-Bmal1 regulates cellular senescence in Chronic obstructive pulmonary disease

Lingling Li, Min Zhang, Chunyang Zhao, Yusheng Cheng, Chuanmei Liu, Minhua Shi

BMC Pulm Med. 2022; 22: 435. Published online 2022 Nov 22. doi: 10.1186/s12890-022-02237-y

PMCID:: PMC9682805

Abstract Article PDF–5.5M

Select item 968252914.

Down-regulation of BMAL1 by MiR-494-3p Promotes Hepatocellular Carcinoma Growth and Metastasis by Increasing GPAM-mediated Lipid Biosynthesis

Yi Yang, Tao Yang, Zifeng Zhao, Hongxin Zhang, Peng Yuan, Gang Wang, Zheng Zhao, Jiaze An, Zhuomin Lyu, Jinliang Xing, Jibin Li

Int J Biol Sci. 2022; 18(16): 6129–6144. Published online 2022 Oct 18. doi: 10.7150/ijbs.74951

PMCID:: PMC9682529

Abstract Article PDF–8.5M

Select item 874390515.

Downregulation of Arntl mRNA Expression in Women with Hypertension: A Case-Control Study

Zhengmei Fang, Lijun Zhu, Yuelong Jin, Yan Chen, Weiwei Chang, Yingshui Yao

Kidney Blood Press Res. 2021 Dec; 46(6): 741–748. Published online 2021 Sep 3. doi: 10.1159/000518669

PMCID:: PMC8743905

Abstract Article

Select item 866060216.

BMAL1 may be involved in angiogenesis and peritumoral cerebral edema of human glioma by regulating VEGF and ANG2

Fan Wang, CaiYan Li, Fei Han, LvAn Chen, Ling Zhu

Aging (Albany NY) 2021 Nov 30; 13(22): 24675–24685. Published online 2021 Nov 23. doi: 10.18632/aging.203708

PMCID:: PMC8660602

Abstract Article PDF–4.9M

Select item 864810917.

NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1

Yang Shen, Mehari Endale, Wei Wang, Andrew R. Morris, Lauren J. Francey, Rachel L. Harold, David W. Hammers, Zhiguang Huo, Carrie L. Partch, John B. Hogenesch, Zhao-Hui Wu, Andrew C. Liu

PLoS Genet. 2021 Nov; 17(11): e1009933. Published online 2021 Nov 22. doi: 10.1371/journal.pgen.1009933

PMCID:: PMC8648109

Abstract Article PDF–2.6M

Select item 844353618.

The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

Xiaodong Zhuang, Senko Tsukuda, Florian Wrensch, Peter A.C. Wing, Mirjam Schilling, James M. Harris, Helene Borrmann, Sophie B. Morgan, Jennifer L. Cane, Laurent Mailly, Nazia Thakur, Carina Conceicao, Harshmeena Sanghani, Laura Heydmann, Charlotte Bach, Anna Ashton, Steven Walsh, Tiong Kit Tan, Lisa Schimanski, Kuan-Ying A. Huang, Catherine Schuster, Koichi Watashi, Timothy S.C. Hinks, Aarti Jagannath, Sridhar R. Vausdevan, Dalan Bailey, Thomas F. Baumert, Jane A. McKeating

iScience. 2021 Oct 22; 24(10): 103144. Published online 2021 Sep 16. doi: 10.1016/j.isci.2021.103144

PMCID:: PMC8443536

Abstract Article PDF–3.0M

Select item 842923219.

Circadian clock protein BMAL1 regulates melanogenesis through MITF in melanoma cells

Soumyadeep Sarkar, Kenneth I. Porter, Panshak P. Dakup, Rajendra P. Gajula, Bala S. C. Koritala, Ryan Hylton, Michael G. Kemp, Kazumasa Wakamatsu, Shobhan Gaddameedhi

Pigment Cell Melanoma Res. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Pigment Cell Melanoma Res. 2021 Sep; 34(5): 955–965. Published online 2021 Jul 6. doi: 10.1111/pcmr.12998

PMCID:: PMC8429232

Abstract Article PDF–675K

Select item 838406520.

Rewiring of Lactate–Interleukin-1β Autoregulatory Loop with Clock-Bmal1: a Feed-Forward Circuit in Glioma

Pruthvi Gowda, Kirti Lathoria, Shalini Sharma, Shruti Patrick, Sonia B. Umdor, Ellora Sen

Mol Cell Biol. 2021 Sep; 41(9): e00449-20. Prepublished online 2021 Jun 14. Published online 2021 Aug 24. doi: 10.1128/MCB.00449-20

PMCID:: PMC8384065

Abstract Article PDF–4.1M

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