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Items: 1 to 20 of 27

1.
Biallelic mutation of FBXL7 suggests a novel form of Hennekam syndrome
Philip M. Boone, Scott Paterson, Kiana Mohajeri, Wenmiao Zhu, Casie A. Genetti, Derek J. C. Tai, Neeharika Nori, Pankaj B. Agrawal, Carlos A. Bacino, Weimin Bi, Michael E. Talkowski, Benjamin M. Hogan, Lance H. Rodan
Am J Med Genet A. Author manuscript; available in PMC 2023 Apr 7.
Published in final edited form as: Am J Med Genet A. 2020 Jan; 182(1): 189–194. Published online 2019 Oct 21. doi: 10.1002/ajmg.a.61392
PMCID:
PMC10081920
AbstractArticlePDF–289K
2.
Butein promotes ubiquitination-mediated survivin degradation inhibits tumor growth and overcomes chemoresistance
Xin Dong, Wenbin Liu, Xiaoying Li, Yu Gan, Li Zhou, Wei Li, Li Xie
Sci Rep. 2022; 12: 20644. Published online 2022 Nov 30. doi: 10.1038/s41598-022-21839-4
Correction in:
Sci Rep. 2023; 13: 1780.
PMCID:
PMC9712619
AbstractArticlePDF–5.5M
3.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
AbstractArticlePDF–2.8M
4.
FBXL7 Body Hypomethylation Is Frequent in Tumors from the Digestive and Respiratory Tracts and Is Associated with Risk-Factor Exposure
Diego Camuzi, Luisa Aguirre Buexm, Simone de Queiroz Chaves Lourenço, Rachele Grazziotin, Simone Guaraldi, Priscila Valverde, Davy Rapozo, Jill M. Brooks, Hisham Mehanna, Luis Felipe Ribeiro Pinto, Sheila Coelho Soares-Lima
Int J Mol Sci. 2022 Jul; 23(14): 7801. Published online 2022 Jul 15. doi: 10.3390/ijms23147801
PMCID:
PMC9316635
AbstractArticlePDF–14M
5.
Downregulated F-Box/LRR-Repeat Protein 7 Facilitates Pancreatic Cancer Metastasis by Regulating Snail1 for Proteasomal Degradation
Liang Tang, Meng Ji, Xing Liang, Danlei Chen, Anan Liu, Guang Yang, Ligang Shi, Zhiping Fu, Chenghao Shao
Front Genet. 2021; 12: 650090. Published online 2021 Jun 24. doi: 10.3389/fgene.2021.650090
PMCID:
PMC8264591
AbstractArticlePDF–4.2M
6.
BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A
Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng
Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676
PMCID:
PMC7606008
AbstractArticlePDF–2.5M
7.
Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis
Loredana Moro, Daniele Simoneschi, Emma Kurz, Arnaldo A. Arbini, Shaowen Jang, Nicoletta Guaragnella, Sergio Giannattasio, Wei Wang, Yu-An Chen, Geoffrey Pires, Andrew Dang, Elizabeth Hernandez, Payal Kapur, Ankita Mishra, Aristotelis Tsirigos, George Miller, Jer-Tsong Hsieh, Michele Pagano
Nat Cell Biol. Author manuscript; available in PMC 2021 Feb 24.
Published in final edited form as: Nat Cell Biol. 2020 Sep; 22(9): 1130–1142. Published online 2020 Aug 24. doi: 10.1038/s41556-020-0560-6
PMCID:
PMC7484425
AbstractArticlePDF–7.6M
8.
miR‐152‐5p suppresses glioma progression and tumorigenesis and potentiates temozolomide sensitivity by targeting FBXL7
Shiqi Kong, Yanwei Fang, Bingqian Wang, Yingxiao Cao, Runzhi He, Zongmao Zhao
J Cell Mol Med. 2020 Apr; 24(8): 4569–4579. Published online 2020 Mar 9. doi: 10.1111/jcmm.15114
PMCID:
PMC7176889
AbstractArticlePDF–1.4M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
PTEN counteracts FBXL2 to promote IP3R3– and Ca2+–mediated apoptosis limiting tumour growth
Shafi Kuchay, Carlotta Giorgi, Daniele Simoneschi, julia Pagan, Sonia Missiroli, Anita Saraf, Laurence Florens, Michael P. Washburn, Ana Collazo-Lorduy, Mireia Castillo-Martin, Carlos Cordon-Cardo, Said M. Sebti, Paolo Pinton, Michele Pagano
Nature. Author manuscript; available in PMC 2017 Oct 4.
Published in final edited form as: Nature. 2017 Jun 22; 546(7659): 554–558. Published online 2017 Jun 14. doi: 10.1038/nature22965
PMCID:
PMC5627969
AbstractArticlePDF–1.3M
11.
Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis
M Kamran, Z-J Long, D Xu, S-S Lv, B Liu, C-L Wang, J Xu, E W-F Lam, Q Liu
Oncogenesis. 2017 Feb; 6(2): e298. Published online 2017 Feb 20. doi: 10.1038/oncsis.2016.80
PMCID:
PMC5337621
AbstractArticlePDF–2.8M
12.
F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7
Y Liu, T Lear, Y Zhao, J Zhao, C Zou, B B Chen, R K Mallampalli
Cell Death Dis. 2015 Feb; 6(2): e1630. Published online 2015 Feb 5. doi: 10.1038/cddis.2014.585
PMCID:
PMC4669792
AbstractArticlePDF–1.7M
13.
The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin
Yuan Liu, Travis Lear, Olivia Iannone, Sruti Shiva, Catherine Corey, Shristi Rajbhandari, Jacob Jerome, Bill B. Chen, Rama K. Mallampalli
J Biol Chem. 2015 May 8; 290(19): 11843–11852. Published online 2015 Mar 16. doi: 10.1074/jbc.M114.629931
PMCID:
PMC4424325
AbstractArticlePDF–2.5M
14.
Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids
Heung-Woo Park, Amber Dahlin, Szeman Tse, Qing Ling Duan, Brooke Schuemann, Fernando D. Martinez, Stephen P. Peters, Stanley J. Szefler, John J. Lima, Michiaki Kubo, Mayumi Tamari, Kelan G. Tantisira
J Allergy Clin Immunol. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: J Allergy Clin Immunol. 2014 Mar; 133(3): 664–9.e5. Published online 2014 Jan 31. doi: 10.1016/j.jaci.2013.12.1042
PMCID:
PMC4112383
AbstractArticlePDF–142K
15.
Parallel SCF Adaptor Capture Proteomics Reveals a Role for SCFFBXL17 in NRF2 Activation via BACH1 Repressor Turnover
Meng-Kwang Marcus Tan, Hui-Jun Lim, Eric J. Bennett, Yang Shi, J. Wade Harper
Mol Cell. Author manuscript; available in PMC 2014 Oct 10.
Published in final edited form as: Mol Cell. 2013 Oct 10; 52(1): 9–24. Published online 2013 Sep 12. doi: 10.1016/j.molcel.2013.08.018
PMCID:
PMC3981468
AbstractArticlePDF–5.8M
16.
Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population
Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte
PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954
PMCID:
PMC3522587
AbstractArticlePDF–130K
17.
The genetic architecture of economic and political preferences
Daniel J. Benjamin, David Cesarini, Matthijs J. H. M. van der Loos, Christopher T. Dawes, Philipp D. Koellinger, Patrik K. E. Magnusson, Christopher F. Chabris, Dalton Conley, David Laibson, Magnus Johannesson, Peter M. Visscher
Proc Natl Acad Sci U S A. 2012 May 22; 109(21): 8026–8031. Published online 2012 May 7. doi: 10.1073/pnas.1120666109
PMCID:
PMC3361436
AbstractArticlePDF–128K
18.
Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women
Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki
PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695
PMCID:
PMC3349734
AbstractArticlePDF–377K
19.
Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest
Tiffany A Coon, Jennifer R Glasser, Rama K Mallampalli, Bill B Chen
Cell Cycle. 2012 Feb 15; 11(4): 721–729. Published online 2012 Feb 15. doi: 10.4161/cc.11.4.19171
PMCID:
PMC3318106
AbstractArticlePDF–18M
20.
Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN
Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi
J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907
PMCID:
PMC3190826
AbstractArticlePDF–5.7M

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