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Select item 106137381.

ELK4 Promotes Cell Cycle Progression and Stem Cell-like Characteristics in HPV-associated Cervical Cancer by Regulating the FBXO22/PTEN Axis

Fuxian Gao, Chunxiao Wang, Xue Bai, Jianghai Ji, Xinrui Huang

Balkan Med J. 2023 Nov; 40(6): 409–414. Published online 2023 Oct 20. doi: 10.4274/balkanmedj.galenos.2023.2023-4-66

PMCID:: PMC10613738

Abstract Article PDF–1.3M

Select item 105427662.

IGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia

Ke Zheng, Nannan Sha, Guofang Hou, Zhuyun Leng, Qin Zhao, Li Zhang, Lingnan He, Meidong Xu, Yuhui Jiang, Tao Chen

Nat Commun. 2023; 14: 6117. Published online 2023 Sep 30. doi: 10.1038/s41467-023-41658-z

PMCID:: PMC10542766

Abstract Article PDF–2.1M

Select item 88288953.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 85237194.

ELK4-mediated lncRNA SNHG22 promotes gastric cancer progression through interacting with EZH2 and regulating miR-200c-3p/Notch1 axis

Xiaqiong Mao, Tao Ji, Aiguo Liu, Yunqi Weng

Cell Death Dis. 2021 Nov; 12(11): 957. Published online 2021 Oct 18. doi: 10.1038/s41419-021-04228-z

PMCID:: PMC8523719

Abstract Article PDF–4.9M

Select item 83538765.

ELK4 promotes the development of gastric cancer by inducing M2 polarization of macrophages through regulation of the KDM5A-PJA2-KSR1 axis

Lei Zheng, Hongmei Xu, Ya Di, Lanlan Chen, Jiao Liu, Liying Kang, Liming Gao

J Transl Med. 2021; 19: 342. Published online 2021 Aug 9. doi: 10.1186/s12967-021-02915-1

PMCID:: PMC8353876

Abstract Article PDF–3.2M

Select item 80090486.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 75496347.

TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer’s microenvironment

Qianshuo Liu, Lu Zhu, Xiaobai Liu, Jian Zheng, Yunhui Liu, Xuelei Ruan, Shuo Cao, Heng Cai, Zhen Li, Yixue Xue

RNA Biol. 2020; 17(9): 1293–1308. Published online 2020 May 6. doi: 10.1080/15476286.2020.1756055

PMCID:: PMC7549634

Abstract Article PDF–6.8M

Select item 69812068.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 56785819.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 555519010.

Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis

Lu Jiang, Jiannan Xiong, Junsi Zhan, Fengjie Yuan, Ming Tang, Chaohua Zhang, Ziyang Cao, Yongcan Chen, Xiaopeng Lu, Yinglu Li, Hui Wang, Lina Wang, Jiadong Wang, Wei-Guo Zhu, Haiying Wang

J Biol Chem. 2017 Aug 11; 292(32): 13296–13311. Published online 2017 Jun 27. doi: 10.1074/jbc.M117.780130

PMCID:: PMC5555190

Abstract Article PDF–4.1M

Select item 549522511.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 477753812.

Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA

Fujun Qin, Yansu Song, Yanmei Zhang, Loryn Facemire, Henry Frierson, Hui Li

PLoS One. 2016; 11(3): e0150382. Published online 2016 Mar 3. doi: 10.1371/journal.pone.0150382

PMCID:: PMC4777538

Abstract Article PDF–1.4M

Select item 466683013.

Cyclin dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway

Cong Peng, Weiqi Zeng, Juan Su, Yehong Kuang, Yijin He, Shuang Zhao, Jianglin Zhang, Weiya Ma, Ann M. Bode, Zigang Dong, Xiang Chen

Oncogene. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Oncogene. 2016 Mar 3; 35(9): 1170–1179. Published online 2015 Jun 1. doi: 10.1038/onc.2015.175

PMCID:: PMC4666830

Abstract Article PDF–1.2M

Select item 381740414.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat

Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54

PMCID:: PMC3817404

Abstract Article PDF–13M

Select item 341214315.

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

Matthew F. Barber, Eriko Michishita-Kioi, Yuanxin Xi, Luisa Tasselli, Mitomu Kioi, Zarmik Moqtaderi, Ruth I. Tennen, Silvana Paredes, Nicolas L. Young, Kaifu Chen, Kevin Struhl, Benjamin A. Garcia, Or Gozani, Wei Li, Katrin F. Chua

Nature. Author manuscript; available in PMC 2013 Jan 5.

Published in final edited form as: Nature. 2012 Jul 5; 487(7405): 114–118. doi: 10.1038/nature11043

PMCID:: PMC3412143

Abstract Article PDF–1.3M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 285291217.

Characterization of the Human Insulin-induced Gene 2 (INSIG2) Promoter: THE ROLE OF Ets-BINDING MOTIFS

Ana Fernández-Alvarez, María Soledad Alvarez, Carme Cucarella, Marta Casado

J Biol Chem. 2010 Apr 16; 285(16): 11765–11774. Published online 2010 Feb 9. doi: 10.1074/jbc.M109.067447

PMCID:: PMC2852912

Abstract Article PDF–2.0M

Select item 272540218.

Transcriptome Sequencing to Detect Gene Fusions in Cancer

Christopher A. Maher, Chandan Kumar-Sinha, Xuhong Cao, Shanker Kalyana-Sundaram, Bo Han, Xiaojun Jing, Lee Sam, Terrence Barrette, Nallasivam Palanisamy, Arul M. Chinnaiyan

Nature. Author manuscript; available in PMC 2009 Sep 5.

Published in final edited form as: Nature. 2009 Mar 5; 458(7234): 97–101. Published online 2009 Jan 11. doi: 10.1038/nature07638

PMCID:: PMC2725402

Abstract Article PDF–1.0M

Select item 268304719.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67