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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107556772.

The ubiquitin conjugase Rad6 mediates ribosome pausing during oxidative stress

Sezen Meydan, Géssica C. Barros, Vanessa Simões, Lana Harley, Blanche K. Cizubu, Nicholas R. Guydosh, Gustavo M. Silva

Cell Rep. Author manuscript; available in PMC 2023 Dec 29.

Published in final edited form as: Cell Rep. 2023 Nov 28; 42(11): 113359. Published online 2023 Nov 2. doi: 10.1016/j.celrep.2023.113359

PMCID:: PMC10755677

Abstract Article PDF–1.1M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106304454.

RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing

Ahmed Moursy, Antoine Cléry, Stefan Gerhardy, Katharina M. Betz, Sanjana Rao, Jarosław Mazur, Sébastien Campagne, Irene Beusch, Malgorzata M. Duszczyk, Mark D. Robinson, Vikram Govind Panse, Frédéric H.-T. Allain

Nat Commun. 2023; 14: 7166. Published online 2023 Nov 7. doi: 10.1038/s41467-023-42962-4

PMCID:: PMC10630445

Abstract Article PDF–4.6M

Select item 105509745.

Structure–function analysis of histone H2B and PCNA ubiquitination dynamics using deubiquitinase-deficient strains

Kaitlin S. Radmall, Prakash K. Shukla, Andrew M. Leng, Mahesh B. Chandrasekharan

Sci Rep. 2023; 13: 16731. Published online 2023 Oct 4. doi: 10.1038/s41598-023-43969-z

PMCID:: PMC10550974

Abstract Article PDF–1.7M

Select item 102359766.

Paf1 complex subunit Rtf1 stimulates H2B ubiquitylation by interacting with the highly conserved N-terminal helix of Rad6

Tasniem Fetian, Brendan M. McShane, Nicole L. Horan, Donya N. Shodja, Jason D. True, Amber L. Mosley, Karen M. Arndt

Proc Natl Acad Sci U S A. 2023 May 30; 120(22): e2220041120. Published online 2023 May 22. doi: 10.1073/pnas.2220041120

PMCID:: PMC10235976

Abstract Article PDF–3.7M

Select item 102333687.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 102130508.

Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases

Guangxue Liu, Jimin Li, Boxue He, Jiaqi Yan, Jingyu Zhao, Xuejie Wang, Xiaocong Zhao, Jingyan Xu, Yeyao Wu, Simin Zhang, Xiaoli Gan, Chun Zhou, Xiangpan Li, Xinghua Zhang, Xuefeng Chen

Nat Commun. 2023; 14: 3024. Published online 2023 May 25. doi: 10.1038/s41467-023-38617-z

PMCID:: PMC10213050

Abstract Article PDF–1.3M

Select item 100812469.

Mechanism of histone H2B monoubiquitination by Bre1

Fan Zhao, Chad W. Hicks, Cynthia Wolberger

Version 2. bioRxiv. Preprint. 2023 Mar 29 [revised 2023 Aug 28]. doi: 10.1101/2023.03.27.534461

Published in:: Nat Struct Mol Biol. 2023 Oct 23

PMCID:: PMC10081246

Abstract Article PDF–12M

Select item 1003611610.

Structural basis for the Rad6 activation by the Bre1 N-terminal domain

Meng Shi, Jiaqi Zhao, Simin Zhang, Wei Huang, Mengfei Li, Xue Bai, Wenxue Zhang, Kai Zhang, Xuefeng Chen, Song Xiang

eLife. 2023; 12: e84157. Published online 2023 Mar 13. doi: 10.7554/eLife.84157

PMCID:: PMC10036116

Abstract Article PDF–7.0M

Select item 1001834311.

Structure and functional determinants of Rad6–Bre1 subunits in the histone H2B ubiquitin-conjugating complex

Prakash K Shukla, Jesse E Bissell, Sanjit Kumar, Srijana Pokhrel, Sowmiya Palani, Kaitlin S Radmall, Onyeka Obidi, Timothy J Parnell, Julia Brasch, Dennis C Shrieve, Mahesh B Chandrasekharan

Nucleic Acids Res. 2023 Mar 21; 51(5): 2117–2136. Published online 2023 Jan 30. doi: 10.1093/nar/gkad012

PMCID:: PMC10018343

Abstract Article PDF–8.3M

Select item 988117612.

The S. cerevisiae m⁶A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts

Jérémy Scutenaire, Damien Plassard, Mélody Matelot, Tommaso Villa, Julie Zumsteg, Domenico Libri, Bertrand Séraphin

Nucleic Acids Res. 2023 Jan 25; 51(2): 517–535. Published online 2022 Aug 8. doi: 10.1093/nar/gkac640

PMCID:: PMC9881176

Abstract Article PDF–7.3M

Select item 983634813.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 963079214.

Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability

Prakash K. Shukla, Dhiraj Sinha, Andrew M. Leng, Jesse E. Bissell, Shravya Thatipamula, Rajarshi Ganguly, Kaitlin S. Radmall, Jack J. Skalicky, Dennis C. Shrieve, Mahesh B. Chandrasekharan

J Biol Chem. 2022 Nov; 298(11): 102524. Published online 2022 Sep 23. doi: 10.1016/j.jbc.2022.102524

PMCID:: PMC9630792

Abstract Article PDF–4.0M

Select item 920981115.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 897681416.

Yeast Stn1 promotes MCM to circumvent Rad53 control of the S phase checkpoint

Hovik Gasparayan, Chris Caridi, Jeff Julius, Wenyi Feng, Jeff Bachant, Constance I. Nugent

Curr Genet. 2022; 68(2): 165–179. Published online 2022 Feb 12. doi: 10.1007/s00294-022-01228-0

PMCID:: PMC8976814

Abstract Article PDF–6.1M

Select item 879822517.

Structural insights into Ubr1 mediated N-degron polyubiquitination

Man Pan, Qingyun Zheng, Tian Wang, Lujun Liang, Junxiong Mao, Chong Zuo, Ruichao Ding, Huasong Ai, Yuan Xie, Dong Si, Yuanyuan Yu, Lei Liu, Minglei Zhao

Nature. Author manuscript; available in PMC 2022 Jan 28.

Published in final edited form as: Nature. 2021 Dec; 600(7888): 334–338. Published online 2021 Nov 17. doi: 10.1038/s41586-021-04097-8