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Select item 107001381.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105517002.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 102977003.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102333684.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 97153605.

Endoplasmic reticulum–resident protein Sec62 drives colorectal cancer metastasis via MAPK/ATF2/UCA1 axis

Yirong Jin, Yuying Han, Suzhen Yang, Jiayi Cao, Mingzuo Jiang, Jie Liang

Cell Prolif. 2022 Dec; 55(12): e13253. Published online 2022 Oct 5. doi: 10.1111/cpr.13253

PMCID:: PMC9715360

Abstract Article PDF–6.1M

Select item 92098116.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 90079177.

Identification of 14-3-3 Proteins, Polo kinase, and RNA-binding protein Pes4 as Key Regulators of Meiotic Commitment in Budding Yeast

Janardan N. Gavade, Chris M. Puccia, S. Grace Herod, Jonathan C. Trinidad, Luke E. Berchowitz, Soni Lacefield

Curr Biol. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Curr Biol. 2022 Apr 11; 32(7): 1534–1547.e9. Published online 2022 Mar 2. doi: 10.1016/j.cub.2022.02.022

PMCID:: PMC9007917

Abstract Article PDF–2.2M

Select item 86505758.

Fur4‐mediated uracil‐scavenging to screen for surface protein regulators

Katherine M. Paine, Gabrielle B. Ecclestone, Chris MacDonald

Traffic. 2021 Nov; 22(11): 397–408. Published online 2021 Sep 23. doi: 10.1111/tra.12815

PMCID:: PMC8650575

Abstract Article PDF–25M

Select item 85036319.

Rapid inactivation of the yeast Sec complex selectively blocks transport of post-translationally translocated proteins

Jae Kyo Yi, Hidenobu Fujita, Elisabet C. Mandon, Reid Gilmore

J Biol Chem. 2021 Oct; 297(4): 101171. Published online 2021 Sep 4. doi: 10.1016/j.jbc.2021.101171

PMCID:: PMC8503631

Abstract Article PDF–2.4M

Select item 823621110.

Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62

Samuel Itskanov, Katie M. Kuo, James C. Gumbart, Eunyong Park

Nat Struct Mol Biol. Author manuscript; available in PMC 2021 Jul 4.

Published in final edited form as: Nat Struct Mol Biol. 2021 Feb; 28(2): 162–172. Published online 2021 Jan 4. doi: 10.1038/s41594-020-00541-x

PMCID:: PMC8236211

Abstract Article PDF–9.8M

Select item 803178011.

How does Sec63 affect the conformation of Sec61 in yeast?

Pratiti Bhadra, Lalitha Yadhanapudi, Karin Römisch, Volkhard Helms

PLoS Comput Biol. 2021 Mar; 17(3): e1008855. Published online 2021 Mar 29. doi: 10.1371/journal.pcbi.1008855

PMCID:: PMC8031780

Abstract Article PDF–3.1M

Select item 784916512.

Architecture of the active post‐translational Sec translocon

Tsai‐Hsuan Weng, Wieland Steinchen, Birgitta Beatrix, Otto Berninghausen, Thomas Becker, Gert Bange, Jingdong Cheng, Roland Beckmann

EMBO J. 2021 Feb 1; 40(3): e105643. Published online 2020 Dec 11. doi: 10.15252/embj.2020105643

PMCID:: PMC7849165

Abstract Article PDF–1.7M

Select item 771875113.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 768101714.

Overlapping function of Hrd1 and Ste24 in translocon quality control provides robust channel surveillance

Avery M. Runnebohm, Kyle A. Richards, Courtney Broshar Irelan, Samantha M. Turk, Halie E. Vitali, Christopher J. Indovina, Eric M. Rubenstein

J Biol Chem. 2020 Nov 20; 295(47): 16113–16120. Published online 2020 Oct 8. doi: 10.1074/jbc.AC120.016191

PMCID:: PMC7681017

Abstract Article PDF–1.4M

Select item 733518715.

Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes

Keisuke Mochida, Akinori Yamasaki, Kazuaki Matoba, Hiromi Kirisako, Nobuo N. Noda, Hitoshi Nakatogawa

Nat Commun. 2020; 11: 3306. Published online 2020 Jul 3. doi: 10.1038/s41467-020-17163-y

PMCID:: PMC7335187

Abstract Article PDF–3.6M

Select item 727317716.

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau, Stefan Jentsch

Cell Rep. 2020 Jun 2; 31(9): 107680. Published online 2020 Jun 2. doi: 10.1016/j.celrep.2020.107680

PMCID:: PMC7273177

Abstract Article

Select item 674019717.

Degradation of integral membrane proteins modified with the photosensitive degron module requires the cytosolic endoplasmic reticulum–associated degradation pathway

Johannes Scheffer, Sophia Hasenjäger, Christof Taxis

Mol Biol Cell. 2019 Sep 15; 30(20): 2558–2570. doi: 10.1091/mbc.E18-12-0754

PMCID:: PMC6740197

Abstract Article PDF–4.9M

Select item 636703518.

Structure of the post-translational protein translocation machinery of the ER membrane

Xudong Wu, Cerrone Cabanos, Tom A. Rapoport

Nature. Author manuscript; available in PMC 2019 Jun 30.

Published in final edited form as: Nature. 2019 Feb; 566(7742): 136–139. Published online 2018 Dec 31. doi: 10.1038/s41586-018-0856-x

PMCID:: PMC6367035

Abstract Article PDF–3.9M

Select item 634717019.

Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation

Fabio Pereira, Mandy Rettel, Frank Stein, Mikhail M. Savitski, Ian Collinson, Karin Römisch

PLoS One. 2019; 14(1): e0211180. Published online 2019 Jan 25. doi: 10.1371/journal.pone.0211180

PMCID:: PMC6347170

Abstract Article PDF–16M

Select item 592252820.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen

PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319