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Select item 112216161.

Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface

Amber Wilkerson, Seher Yuksel, Riya Acharya, Igor A. Butovich

Invest Ophthalmol Vis Sci. 2024 Jul; 65(8): 2. Published online 2024 Jul 2. doi: 10.1167/iovs.65.8.2

PMCID:: PMC11221616

Abstract Article PDF–8.3M

Select item 111498722.

Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food

Laura Dearden, Isadora C. Furigo, Lucas C. Pantaleão, L W. P. Wong, Denise S. Fernandez-Twinn, Juliana de Almeida-Faria, Katherine A. Kentistou, Maria V. Carreira, Guillaume Bidault, Antonio Vidal-Puig, Ken K. Ong, John R. B. Perry, Jose Donato, Jr, Susan E. Ozanne

PLoS Biol. 2024 Jun; 22(6): e3002641. Published online 2024 Jun 4. doi: 10.1371/journal.pbio.3002641

PMCID:: PMC11149872

Abstract Article PDF–1.7M

Select item 104347153.

Comparative Biophysical Study of Meibomian Lipids of Wild Type and Soat1-Null Mice: Implications to Meibomian Gland Dysfunction and Dry Eye Disease

Xiaojie Xu, Amber Wilkerson, Guangle Li, Igor A. Butovich, Yi Y. Zuo

Invest Ophthalmol Vis Sci. 2023 Aug; 64(11): 20. Published online 2023 Aug 16. doi: 10.1167/iovs.64.11.20

PMCID:: PMC10434715

Abstract Article PDF–8.3M

Select item 98695424.

Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization

Syed A. H. Zaidi, Tahira Lemtalsi, Zhimin Xu, Isabella Santana, Porsche Sandow, Leila Labazi, Robert W. Caldwell, Ruth B. Caldwell, Modesto A. Rojas

J Neuroinflammation. 2023; 20: 14. Published online 2023 Jan 23. doi: 10.1186/s12974-023-02700-5

PMCID:: PMC9869542

Abstract Article PDF–8.0M

Select item 91701415.

Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells

Maximillian A. Rogers, Catherine C. Y. Chang, Robert A. Maue, Elaina M. Melton, Andrew A. Peden, William S. Garver, Junghoon Lee, Peter Schroen, Mitchell Huang, Ta-Yuan Chang

Proc Natl Acad Sci U S A. 2022 May 3; 119(18): e2201646119. Published online 2022 May 4. doi: 10.1073/pnas.2201646119

PMCID:: PMC9170141

Abstract Article PDF–2.7M

Select item 88558126.

Ceramide-mediated gut dysbiosis enhances cholesterol esterification and promotes colorectal tumorigenesis in mice

Yahui Zhu, Li Gu, Xi Lin, Jinmiao Zhang, Yi Tang, Xinyi Zhou, Bingjun Lu, Xingrong Lin, Cheng Liu, Edward V. Prochownik, Youjun Li

JCI Insight. 2022 Feb 8; 7(3): e150607. Published online 2022 Feb 8. doi: 10.1172/jci.insight.150607

PMCID:: PMC8855812

Abstract Article PDF–15M

Select item 79155377.

Depletion of Cholesteryl Esters Causes Meibomian Gland Dysfunction-Like Symptoms in a Soat1-Null Mouse Model

Igor A. Butovich, Amber Wilkerson, Seher Yuksel

Int J Mol Sci. 2021 Feb; 22(4): 1583. Published online 2021 Feb 4. doi: 10.3390/ijms22041583

PMCID:: PMC7915537

Abstract Article PDF–3.9M

Select item 76862758.

Soat1 mediates the mouse strain effects on cholesterol loading-induced endoplasmic reticulum stress and CHOP expression in macrophages

Mengdie Luo, Emmanuel Opoku, C. Alicia Traughber, Qimin Hai, Peggy Robinet, Stela Berisha, Jonathan D. Smith

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Jan; 1866(1): 158825. Published online 2020 Oct 6. doi: 10.1016/j.bbalip.2020.158825

PMCID:: PMC7686275

Abstract Article PDF–881K

Select item 75766719.

Circ-Tulp4 promotes β-cell adaptation to lipotoxicity by regulating soat1 expression

Liting Wu, Li Xiong, Jin Li, Zishan Peng, Luyao Zhang, Peijie Shi, Yingying Gong, Haipeng Xiao

J Mol Endocrinol. 2020 Nov; 65(4): 149–161. Published online 2020 Sep 11. doi: 10.1530/JME-20-0079

PMCID:: PMC7576671

Abstract Article PDF–3.5M

Select item 741599110.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 736982311.

A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression

Michishige Terasaki, Hironori Yashima, Yusaku Mori, Tomomi Saito, Takanori Matsui, Munenori Hiromura, Hideki Kushima, Naoya Osaka, Makoto Ohara, Tomoyasu Fukui, Tsutomu Hirano, Sho-ichi Yamagishi

Int J Mol Sci. 2020 Jul; 21(13): 4811. Published online 2020 Jul 7. doi: 10.3390/ijms21134811

PMCID:: PMC7369823

Abstract Article PDF–991K

Select item 721637112.

Involvement of ABC-transporters and acyltransferase 1 in intracellular cholesterol-mediated autophagy in bovine alveolar macrophages in response to the Bacillus Calmette-Guerin (BCG) infection

Jinrui Xu, Yanbing Zhou, Yi Yang, Cuiping Lv, Xiaoming Liu, Yujiong Wang

BMC Immunol. 2020; 21: 26. Published online 2020 May 12. doi: 10.1186/s12865-020-00356-x

PMCID:: PMC7216371

Abstract Article PDF–1.8M

Select item 713233813.

USP1 deubiquitinates Akt to inhibit PI3K‐Akt‐FoxO signaling in muscle during prolonged starvation

Dana Goldbraikh, Danielle Neufeld, Yara Eid‐Mutlak, Inbal Lasry, Jennifer E Gilda, Anna Parnis, Shenhav Cohen

EMBO Rep. 2020 Apr 3; 21(4): e48791. Published online 2020 Mar 5. doi: 10.15252/embr.201948791

PMCID:: PMC7132338

Abstract Article PDF–1.6M

Select item 681608614.

Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions

Elaina M. Melton, Haibo Li, Jalen Benson, Paul Sohn, Li-Hao Huang, Bao-Liang Song, Bo-Liang Li, Catherine C. Y. Chang, Ta-Yuan Chang

J Biol Chem. 2019 Oct 25; 294(43): 15836–15849. Published online 2019 Sep 8. doi: 10.1074/jbc.RA119.010564

PMCID:: PMC6816086

Abstract Article PDF–4.3M

Select item 666870215.

ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes

G. Michelle Ducasa, Alla Mitrofanova, Shamroop K. Mallela, Xiaochen Liu, Judith Molina, Alexis Sloan, Christopher E. Pedigo, Mengyuan Ge, Javier Varona Santos, Yanio Hernandez, Jin-Ju Kim, Cyrille Maugeais, Armando J. Mendez, Viji Nair, Matthias Kretzler, George W. Burke, Robert G. Nelson, Yu Ishimoto, Reiko Inagi, Santanu Banerjee, Shaoyi Liu, Hazel H. Szeto, Sandra Merscher, Flavia Fontanesi, Alessia Fornoni

J Clin Invest. 2019 Aug 1; 129(8): 3387–3400. Published online 2019 Jul 22. doi: 10.1172/JCI125316

PMCID:: PMC6668702

Abstract Article PDF–11M

Select item 640288416.

Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells

Hisataka Yamazaki, Manabu Takahashi, Tetsuji Wakabayashi, Kent Sakai, Daisuke Yamamuro, Akihito Takei, Shoko Takei, Shuichi Nagashima, Hiroaki Yagyu, Motohiro Sekiya, Ken Ebihara, Shun Ishibashi

J Atheroscler Thromb. 2019 Mar 1; 26(3): 246–259. doi: 10.5551/jat.44040

PMCID:: PMC6402884

Abstract Article PDF–1.4M

Select item 617100817.

Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity

Li-Hao Huang, Elaina M. Melton, Haibo Li, Paul Sohn, DaeYoung Jung, Ching-Yi Tsai, Tian Ma, Hiroyuki Sano, HyeKyung Ha, Randall H. Friedline, Jason K. Kim, Edward Usherwood, Catherine C. Y. Chang, Ta-Yuan Chang

Am J Physiol Endocrinol Metab. 2018 Sep 1; 315(3): E340–E356. Published online 2018 Mar 13. doi: 10.1152/ajpendo.00174.2017

PMCID:: PMC6171008

Abstract Article

Select item 592842518.

In vitro exploration of ACAT contributions to lipid droplet formation during adipogenesis

Yuyan Zhu, Chih-Yu Chen, Junjie Li, Ji-Xin Cheng, Miran Jang, Kee-Hong Kim

J Lipid Res. 2018 May; 59(5): 820–829. Published online 2018 Mar 16. doi: 10.1194/jlr.M081745

PMCID:: PMC5928425

Abstract Article PDF–1.1M

Select item 574647519.

QTL Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant

Qimin Hai, Brian Ritchey, Peggy Robinet, Alexander M. Alzayed, Greg Brubaker, Jinying Zhang, Jonathan D. Smith

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Jan; 38(1): 83–91. Published online 2017 Nov 2. doi: 10.1161/ATVBAHA.117.310173

PMCID:: PMC5746475

Abstract Article PDF–1002K

Select item 534152020.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

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PMC Links for GEO Profiles (Select 62311027) (59)
PMC
tudor domain-containing protein 5 isoform X3 [Mus musculus]
tudor domain-containing protein 5 isoform X3 [Mus musculus]
gi|568910617|ref|XP_006496791.1|

Protein
PREDICTED: Mus musculus tudor domain containing 5 (Tdrd5), transcript variant X8...
PREDICTED: Mus musculus tudor domain containing 5 (Tdrd5), transcript variant X8, mRNA
gi|1720354616|ref|XM_006496733.3|

Nucleotide
tudor domain-containing protein 5 isoform X2 [Mus musculus]
tudor domain-containing protein 5 isoform X2 [Mus musculus]
gi|568910615|ref|XP_006496790.1|

Protein

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