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Items: 1 to 20 of 62

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology
Archana D. Siddam, Matthieu Duot, Sarah Y. Coomson, Deepti Anand, Sandeep Aryal, Bailey A. T. Weatherbee, Yann Audic, Luc Paillard, Salil A. Lachke
Cells. 2023 Apr; 12(7): 1070. Published online 2023 Apr 1. doi: 10.3390/cells12071070
PMCID:
PMC10093462
AbstractArticlePDF–3.8M
3.
Long noncoding RNA uc.230/CUG-binding protein 1 axis sustains intestinal epithelial homeostasis and response to tissue injury
Ting-Xi Yu, Sudhakar Kalakonda, Xiangzheng Liu, Naomi Han, Hee K. Chung, Lan Xiao, Jaladanki N. Rao, Tong-Chuan He, Jean-Pierre Raufman, Jian-Ying Wang
JCI Insight. 2022 Oct 10; 7(19): e156612. Published online 2022 Oct 10. doi: 10.1172/jci.insight.156612
PMCID:
PMC9675575
AbstractArticlePDF–14M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development
Sandeep Aryal, Justine Viet, Bailey A. T. Weatherbee, Archana D. Siddam, Francisco G. Hernandez, Carole Gautier-Courteille, Luc Paillard, Salil A. Lachke
Hum Genet. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: Hum Genet. 2020 Dec; 139(12): 1541–1554. Published online 2020 Jun 27. doi: 10.1007/s00439-020-02195-7
PMCID:
PMC7572558
AbstractArticlePDF–1.5M
8.
Increased nuclear but not cytoplasmic activities of CELF1 protein leads to muscle wasting
Diana C Cox, Xiangnan Guan, Zheng Xia, Thomas A Cooper
Hum Mol Genet. 2020 Jun 27; 29(10): 1729–1744. Published online 2020 May 15. doi: 10.1093/hmg/ddaa095
PMCID:
PMC7322576
AbstractArticlePDF–2.6M
9.
Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development
Tatiana Popovitchenko, Yongkyu Park, Nicholas F. Page, Xiaobing Luo, Zeljka Krsnik, Yuan Liu, Iva Salamon, Jessica D. Stephenson, Matthew L. Kraushar, Nicole L. Volk, Sejal M. Patel, H. R. Sagara Wijeratne, Diana Li, Kandarp S. Suthar, Aaron Wach, Miao Sun, Sebastian J. Arnold, Wado Akamatsu, Hideyuki Okano, Luc Paillard, Huaye Zhang, Steven Buyske, Ivica Kostovic, Silvia De Rubeis, Ronald P. Hart, Mladen-Roko Rasin
Nat Commun. 2020; 11: 1674. Published online 2020 Apr 3. doi: 10.1038/s41467-020-15412-8
PMCID:
PMC7125149
AbstractArticlePDF–6.6M
10.
Aberrant expression of a non-muscle RBFOX2 isoform triggers cardiac conduction defects in myotonic dystrophy
Chaitali Misra, Sushant Bangru, Feikai Lin, Kin Lam, Sara N. Koenig, Ellen R. Lubbers, Jamila Hedhli, Nathaniel P. Murphy, Darren J. Parker, Lawrence W. Dobrucki, Thomas A. Cooper, Emad Tajkhorshid, Peter J. Mohler, Auinash Kalsotra
Dev Cell. Author manuscript; available in PMC 2021 Mar 23.
Published in final edited form as: Dev Cell. 2020 Mar 23; 52(6): 748–763.e6. Published online 2020 Feb 27. doi: 10.1016/j.devcel.2020.01.037
PMCID:
PMC7098852
AbstractArticlePDF–3.4M
11.
HNRNPA1-induced spliceopathy in a transgenic mouse model of myotonic dystrophy
Moyi Li, Yan Zhuang, Ranjan Batra, James D. Thomas, Mao Li, Curtis A. Nutter, Marina M. Scotti, Helmut A. Carter, Zhan Jun Wang, Xu-Sheng Huang, Chuan Qiang Pu, Maurice S. Swanson, Wei Xie
Proc Natl Acad Sci U S A. 2020 Mar 10; 117(10): 5472–5477. Published online 2020 Feb 21. doi: 10.1073/pnas.1907297117
PMCID:
PMC7071875
AbstractArticlePDF–1.3M
12.
CELF1 contributes to aberrant alternative splicing patterns in the Type 1 diabetic heart
KarryAnne Belanger, Curtis A. Nutter, Jin Li, Sadia Tasnim, Peiru Liu, Peng Yu, Muge N. Kuyumcu-Martinez
Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Sep 18.
Published in final edited form as: Biochem Biophys Res Commun. 2018 Sep 18; 503(4): 3205–3211. Published online 2018 Aug 27. doi: 10.1016/j.bbrc.2018.08.126
PMCID:
PMC6142808
AbstractArticlePDF–769K
13.
Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation
Amber M. D’Souza, Yanjun Jiang, Ashley Cast, Leila Valanejad, Mary Wright, Kyle Lewis, Meenasri Kumbaji, Sheeniza Shah, David Smithrud, Rebekah Karns, Soona Shin, Nikolai Timchenko
Cell Mol Gastroenterol Hepatol. 2018; 6(3): 239–255. Published online 2018 May 24. doi: 10.1016/j.jcmgh.2018.05.007
PMCID:
PMC6083020
AbstractArticlePDF–5.1M
14.
Correction of GSK3β at young age prevents muscle pathology in mice with myotonic dystrophy type 1
Christina Wei, Lauren Stock, Leila Valanejad, Zachary A. Zalewski, Rebekah Karns, Jack Puymirat, David Nelson, David Witte, Jim Woodgett, Nikolai A. Timchenko, Lubov Timchenko
FASEB J. 2018 Apr; 32(4): 2073–2085. Published online 2018 Jan 5. doi: 10.1096/fj.201700700R
PMCID:
PMC5893173
AbstractArticle
15.
The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development
Archana D. Siddam, Carole Gautier-Courteille, Linette Perez-Campos, Deepti Anand, Atul Kakrana, Christine A. Dang, Vincent Legagneux, Agnès Méreau, Justine Viet, Jeffrey M. Gross, Luc Paillard, Salil A. Lachke
PLoS Genet. 2018 Mar; 14(3): e1007278. Published online 2018 Mar 22. doi: 10.1371/journal.pgen.1007278
PMCID:
PMC5889275
AbstractArticlePDF–19M
16.
FXR-Gankyrin axis is involved in development of pediatric liver cancer
Leila Valanejad, Kyle Lewis, Mary Wright, Yanjun Jiang, Amber D’Souza, Rebekah Karns, Rachel Sheridan, Anita Gupta, Kevin Bove, David Witte, James Geller, Gregory Tiao, David L. Nelson, Lubov Timchenko, Nikolai Timchenko
Carcinogenesis. 2017 Jul; 38(7): 738–747. Published online 2017 May 23. doi: 10.1093/carcin/bgx050
PMCID:
PMC5862323
AbstractArticlePDF–15M
17.
Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions
Amy E Brinegar, Zheng Xia, James Anthony Loehr, Wei Li, George Gerald Rodney, Thomas A Cooper
eLife. 2017; 6: e27192. Published online 2017 Aug 11. doi: 10.7554/eLife.27192
PMCID:
PMC5577920
AbstractArticlePDF–3.6M
18.
Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators
Zhiqiang Bai, Xiao-ran Chai, Myeong Jin Yoon, Hye-Jin Kim, Kinyui Alice LO, Zhi-chun Zhang, Dan Xu, Diana Teh Chee Siang, Arcinas Camille Esther Walet, Shao-hai Xu, Sook-Yoong Chia, Peng Chen, Hongyuan Yang, Sujoy Ghosh, Lei Sun
PLoS Biol. 2017 Aug; 15(8): e2002176. Published online 2017 Aug 1. doi: 10.1371/journal.pbio.2002176
PMCID:
PMC5538645
AbstractArticlePDF–9.2M
19.
RNA Binding Protein CUGBP1 Inhibits Liver Cancer in a Phosphorylation-Dependent Manner
Kyle Lewis, Leila Valanejad, Ashley Cast, Mary Wright, Christina Wei, Polina Iakova, Lauren Stock, Rebekah Karns, Lubov Timchenko, Nikolai Timchenko
Mol Cell Biol. 2017 Aug 15; 37(16): e00128-17. Prepublished online 2017 May 30. Published online 2017 Jul 28. doi: 10.1128/MCB.00128-17
PMCID:
PMC5533886
AbstractArticlePDF–5.4M
20.
The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts
Joseph Russo, Jerome E. Lee, Carolina M. López, John Anderson, Thuy-mi P. Nguyen, Adam M. Heck, Jeffrey Wilusz, Carol J. Wilusz
PLoS One. 2017; 12(1): e0170680. Published online 2017 Jan 27. doi: 10.1371/journal.pone.0170680
PMCID:
PMC5271678
AbstractArticlePDF–1.7M

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