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Select item 109457071.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 103675592.

FOXM1-regulated ZIC2 promotes the malignant phenotype of renal clear cell carcinoma by activating UBE2C/mTOR signaling pathway

Zhengtong Lv, Miao Wang, Huimin Hou, Guyu Tang, Haozhe Xu, Xuan Wang, Yuan Li, Jianye Wang, Ming Liu

Int J Biol Sci. 2023; 19(11): 3293–3306. Published online 2023 Jun 26. doi: 10.7150/ijbs.84067

PMCID:: PMC10367559

Abstract Article PDF–8.0M

Select item 103620103.

ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis

Qian Liu, Ting Yang, Yu Zhang, Ze-Dong Hu, Yan-Min Liu, Yi-Ling Luo, Shang-Xin Liu, Hua Zhang, Qian Zhong

Cell Death Dis. 2023 Jul; 14(7): 455. Published online 2023 Jul 21. doi: 10.1038/s41419-023-05983-x

PMCID:: PMC10362010

Abstract Article PDF–6.1M

Select item 83124654.

Downregulation of LINC00665 suppresses the progression of lung adenocarcinoma via regulating miR-181c-5p/ZIC2 axis

Wei Wei, Xiaoliang Zhao, Jiang Liu, Zhenfa Zhang

Aging (Albany NY) 2021 Jul 15; 13(13): 17499–17515. Published online 2021 Jul 7. doi: 10.18632/aging.203240

PMCID:: PMC8312465

Abstract Article PDF–2.6M

Select item 82813135.

ZIC2 upregulates lncRNA SNHG12 expression to promote endometrial cancer cell proliferation and migration by activating the Notch signaling pathway

Pengyu Cai, Gaijuan Li, Mingxiu Wu, Bin Zhang, Hong Bai

Mol Med Rep. 2021 Sep; 24(3): 632. Published online 2021 Jul 5. doi: 10.3892/mmr.2021.12271

PMCID:: PMC8281313

Abstract Article PDF–6.1M

Select item 81849916.

Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin

Zhengshui Xu, Jianbao Zheng, Zilu Chen, Jing Guo, Xiaopeng Li, Xingjie Wang, Chao Qu, Liyue Yuan, Chen Cheng, Xuejun Sun, Junhui Yu

Cell Death Dis. 2021 Jun; 12(6): 584. Published online 2021 Jun 7. doi: 10.1038/s41419-021-03863-w

PMCID:: PMC8184991

Abstract Article PDF–2.8M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79138308.

De Novo PORCN and ZIC2 Mutations in a Highly Consanguineous Family

Laura Castilla-Vallmanya, Semra Gürsoy, Özlem Giray-Bozkaya, Aina Prat-Planas, Gemma Bullich, Leslie Matalonga, Mónica Centeno-Pla, Raquel Rabionet, Daniel Grinberg, Susanna Balcells, Roser Urreizti

Int J Mol Sci. 2021 Feb; 22(4): 1549. Published online 2021 Feb 4. doi: 10.3390/ijms22041549

PMCID:: PMC7913830

Abstract Article PDF–9.0M

Select item 78484479.

miR-1284 Inhibits the Growth and Invasion of Breast Cancer Cells by Targeting ZIC2

Pengcheng Zhang, Fang Yang, Qin Luo, Daxue Yan, Shengrong Sun

Oncol Res. 2019; 27(2): 253–260. Published online 2019 Feb 5. doi: 10.3727/096504018X15242763477504

PMCID:: PMC7848447

Abstract Article PDF–5.2M

Select item 782318710.

Correlation of zinc finger protein 2, a prognostic biomarker, with immune infiltrates in liver cancer

Lei Sun, Yaru Lin, Guichun Wang, Lin Zhang, Liangchang Hu, Zhong Lu

Biosci Rep. 2021 Jan 29; 41(1): BSR20203115. Published online 2021 Jan 22. doi: 10.1042/BSR20203115

PMCID:: PMC7823187

Abstract Article PDF–1.4M

Select item 754388611.

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

Abhik K. Banerjee, Mario R. Blanco, Emily A. Bruce, Drew D. Honson, Linlin M. Chen, Amy Chow, Prashant Bhat, Noah Ollikainen, Sofia A. Quinodoz, Colin Loney, Jasmine Thai, Zachary D. Miller, Aaron E. Lin, Madaline M. Schmidt, Douglas G. Stewart, Daniel Goldfarb, Giuditta De Lorenzo, Suzannah J. Rihn, Rebecca M. Voorhees, Jason W. Botten, Devdoot Majumdar, Mitchell Guttman

Cell. 2020 Nov 25; 183(5): 1325–1339.e21. doi: 10.1016/j.cell.2020.10.004

PMCID:: PMC7543886

Abstract Article

Select item 694204412.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 680533813.

Random forest-based modelling to detect biomarkers for prostate cancer progression

Reka Toth, Heiko Schiffmann, Claudia Hube-Magg, Franziska Büscheck, Doris Höflmayer, Sören Weidemann, Patrick Lebok, Christoph Fraune, Sarah Minner, Thorsten Schlomm, Guido Sauter, Christoph Plass, Yassen Assenov, Ronald Simon, Jan Meiners, Clarissa Gerhäuser

Clin Epigenetics. 2019; 11: 148. Published online 2019 Oct 22. doi: 10.1186/s13148-019-0736-8

PMCID:: PMC6805338

Abstract Article PDF–2.6M

Select item 629779514.

miR-1271-5p inhibits cell proliferation and induces apoptosis in acute myeloid leukemia by targeting ZIC2

Xiaohe Chen, Shouhang Yang, Jue Zeng, Ming Chen

Mol Med Rep. 2019 Jan; 19(1): 508–514. Published online 2018 Nov 21. doi: 10.3892/mmr.2018.9680

PMCID:: PMC6297795

Abstract Article PDF–1.0M

Select item 607643915.

The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation

Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin

Cancer Res. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342

PMCID:: PMC6076439

Abstract Article PDF–2.5M

Select item 604127016.

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity

Iain M. Dykes, Dorota Szumska, Linta Kuncheria, Rathi Puliyadi, Chiann-mun Chen, Costis Papanayotou, Helen Lockstone, Christèle Dubourg, Véronique David, Jurgen E. Schneider, Thomas M. Keane, David J. Adams, Steve D. M. Brown, Sandra Mercier, Sylvie Odent, Jérôme Collignon, Shoumo Bhattacharya

Sci Rep. 2018; 8: 10439. Published online 2018 Jul 11. doi: 10.1038/s41598-018-28714-1

PMCID:: PMC6041270

Abstract Article PDF–2.7M

Select item 576315717.

In-depth investigations of adolescents and adults with holoprosencephaly identify unique characteristics

Karin Weiss, Paul Kruszka, Maria J Guillen Sacoto, Yonit A Addissie, Donald W Hadley, Casey K Hadsall, Bethany Stokes, Ping Hu, Erich Roessler, Beth Solomon, Edythe Wiggs, Audrey Thurm, Robert B Hufnagel, Wadih M Zein, Jin S Hahn, Elaine Stashinko, Eric Levey, Debbie Baldwin, Nancy J Clegg, Mauricio R Delgado, Maximilian Muenke

Genet Med. 2018 Jan; 20(1): 14–23. Published online 2017 Jun 22. doi: 10.1038/gim.2017.68

PMCID:: PMC5763157

Abstract Article PDF–1004K

Select item 553161118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 480585519.

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

Javier Rodriguez, Ruth Pilkington, Amaya Garcia Munoz, Lan K. Nguyen, Nora Rauch, Susan Kennedy, Naser Monsefi, Ana Herrero, Cormac T. Taylor, Alex von Kriegsheim

Cell Rep. 2016 Mar 22; 14(11): 2745–2760. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.043

PMCID:: PMC4805855

Abstract Article PDF–4.6M

Select item 469505820.

Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2

Shingo Inaguma, Hideaki Ito, Miho Riku, Hiroshi Ikeda, Kenji Kasai

Oncotarget. 2015 Sep 29; 6(29): 28257–28268. Published online 2015 Jul 22. doi: 10.18632/oncotarget.4960

PMCID:: PMC4695058

Abstract Article PDF–2.8M

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