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Select item 100167081.

HPV upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer

Mohamed I. Khalil, Canchai Yang, Lexi Vu, Smriti Chadha, Harrison Nabors, Craig Welbon, Claire D. James, Iain M. Morgan, William C. Spanos, Dohun Pyeon

PLoS Pathog. 2023 Mar; 19(3): e1011171. Published online 2023 Mar 3. doi: 10.1371/journal.ppat.1011171

PMCID:: PMC10016708

Abstract Article PDF–4.7M

Select item 87746392.

Associations of Single-Nucleotide Polymorphisms in Slovenian Patients with Acute Central Serous Chorioretinopathy

Peter Kiraly, Andrej Zupan, Alenka Matjašič, Polona Jaki Mekjavić

Genes (Basel) 2022 Jan; 13(1): 55. Published online 2021 Dec 25. doi: 10.3390/genes13010055

PMCID:: PMC8774639

Abstract Article PDF–1.0M

Select item 83311883.

Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization

Joshua D Greenlee, Maria Lopez-Cavestany, Nerymar Ortiz-Otero, Kevin Liu, Tejas Subramanian, Burt Cagir, Michael R King

eLife. 2021; 10: e67750. Published online 2021 Aug 3. doi: 10.7554/eLife.67750

PMCID:: PMC8331188

Abstract Article PDF–6.3M

Select item 82299744.

Epigenetic Modification of Death Receptor Genes for TRAIL and TRAIL Resistance in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia

Atsushi Watanabe, Kunio Miyake, Koshi Akahane, Kumiko Goi, Keiko Kagami, Hideo Yagita, Takeshi Inukai

Genes (Basel) 2021 Jun; 12(6): 864. Published online 2021 Jun 5. doi: 10.3390/genes12060864

PMCID:: PMC8229974

Abstract Article PDF–4.1M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79143516.

Downregulation of death receptor 4 is tightly associated with positive response of EGFR mutant lung cancer to EGFR-targeted therapy and improved prognosis

Shuo Zhang, Zhen Chen, Puyu Shi, Songqing Fan, Yong He, Qiming Wang, Yixiang Li, Suresh S. Ramalingam, Taofeek K. Owonikoko, Shi-Yong Sun

Theranostics. 2021; 11(8): 3964–3980. Published online 2021 Feb 15. doi: 10.7150/thno.54824

PMCID:: PMC7914351

Abstract Article PDF–3.6M

Select item 68497997.

Death receptor 5 is activated by fucosylation in colon cancer cells

Baojie Zhang, Ingrid A. M. van Roosmalen, Carlos R. Reis, Rita Setroikromo, Wim J. Quax

FEBS J. 2019 Feb; 286(3): 555–571. Published online 2019 Jan 14. doi: 10.1111/febs.14742

PMCID:: PMC6849799

Abstract Article PDF–1.5M

Select item 67575738.

Lack of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand But Presence of Its Receptors in the Human Brain

Jan Dörr, Ingo Bechmann, Sonia Waiczies, Orhan Aktas, Henning Walczak, Peter H. Krammer, Robert Nitsch, Frauke Zipp

J Neurosci. 2002 Feb 15; 22(4): RC209. doi: 10.1523/JNEUROSCI.22-04-j0001.2002

PMCID:: PMC6757573

Abstract PDF–690K

Select item 65030359.

TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes

Julian Staniek, Raquel Lorenzetti, Bianca Heller, Iga Janowska, Pascal Schneider, Susanne Unger, Klaus Warnatz, Maximilian Seidl, Nils Venhoff, Jens Thiel, Cristian Roberto Smulski, Marta Rizzi

Front Immunol. 2019; 10: 951. Published online 2019 Apr 30. doi: 10.3389/fimmu.2019.00951

PMCID:: PMC6503035

Abstract Article PDF–5.3M

Select item 606983810.

Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC

Jan-Paul Gundlach, Charlotte Hauser, Franka Maria Schlegel, Christine Böger, Christian Röder, Christoph Röcken, Thomas Becker, Jan-Hendrik Egberts, Holger Kalthoff, Anna Trauzold

BMC Cancer. 2018; 18: 777. Published online 2018 Jul 31. doi: 10.1186/s12885-018-4688-8

PMCID:: PMC6069838

Abstract Article PDF–1.5M

Select item 568058811.

Secretory stressors induce intracellular death receptor accumulation to control apoptosis

Bram J van Raam, Tamara Lacina, Ralph K Lindemann, Jan H Reiling

Cell Death Dis. 2017 Oct; 8(10): e3069. Published online 2017 Oct 5. doi: 10.1038/cddis.2017.466

PMCID:: PMC5680588

Abstract Article PDF–3.3M

Select item 567858112.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 563060013.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 538051115.

A genome-wide loss-of-function screen identifies SLC26A2 as a novel mediator of TRAIL resistance

Lina Y. Dimberg, Christina G. Towers, Kian Behbakht, Taylor J. Hotz, Jihye Kim, Susan Fosmire, Christopher C. Porter, Aik-Choon Tan, Andrew Thorburn, Heide L. Ford

Mol Cancer Res. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Mol Cancer Res. 2017 Apr; 15(4): 382–394. Published online 2017 Jan 20. doi: 10.1158/1541-7786.MCR-16-0234

PMCID:: PMC5380511

Abstract Article PDF–1.7M

Select item 535478516.

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress

Florent Dufour, Thibault Rattier, Andrei Alexandru Constantinescu, Luciana Zischler, Aymeric Morlé, Hazem Ben Mabrouk, Etienne Humblin, Guillaume Jacquemin, Eva Szegezdi, Fabien Delacote, Naziha Marrakchi, Gilles Guichard, Catherine Pellat-Deceunynck, Pierre Vacher, Patrick Legembre, Carmen Garrido, Olivier Micheau

Oncotarget. 2017 Feb 7; 8(6): 9974–9985. Published online 2016 Dec 27. doi: 10.18632/oncotarget.14285

PMCID:: PMC5354785

Abstract Article PDF–5.2M

Select item 507683817.

Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition

Weilong Yao, You-Take Oh, Jiusheng Deng, Ping Yue, Liang Deng, Henry Huang, Wei Zhou, Shi-Yong Sun

J Biol Chem. 2016 Oct 7; 291(41): 21694–21702. Published online 2016 Aug 30. doi: 10.1074/jbc.M116.738302

Correction in:: J Biol Chem. 2020 Jun 26; 295(26): 8871.

PMCID:: PMC5076838

Abstract Article PDF–1.7M

Select item 479256718.

Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B

Jie Zheng, Hye Lim Lee, Young Wan Ham, Ho Sueb Song, Min Jong Song, Jin Tae Hong

Oncotarget. 2015 Dec 29; 6(42): 44437–44451. Published online 2015 Oct 30. doi: 10.18632/oncotarget.6295

PMCID:: PMC4792567

Abstract Article PDF–6.4M

Select item 460159119.

The structure of the death receptor 4–TNF-related apoptosis-inducing ligand (DR4–TRAIL) complex

Vidhyashankar Ramamurthy, Aaron P. Yamniuk, Eric J. Lawrence, Wei Yong, Lumelle A. Schneeweis, Lin Cheng, Melissa Murdock, Martin J. Corbett, Michael L. Doyle, Steven Sheriff

Acta Crystallogr F Struct Biol Commun. 2015 Oct 1; 71(Pt 10): 1273–1281. Published online 2015 Sep 23. doi: 10.1107/S2053230X15016416

PMCID:: PMC4601591

Abstract Article PDF–1.6M

Select item 455196820.

Genetic association between TRAIL-R1 Thr209Arg and cancer susceptibility

Peiliang Geng, Jianjun Li, Ning Wang, Yunmei Liao, Juanjuan Ou, Rina Sa, Ganfeng Xie, Chen Liu, Hongtao Li, Lisha Xiang, Houjie Liang

Sci Rep. 2015; 5: 10382. Published online 2015 Aug 28. doi: 10.1038/srep10382

PMCID:: PMC4551968

Abstract Article PDF–710K

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PMC Links for GEO Profiles (Select 63262545) (95)
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Conserved Domain Links for Protein (Select 499680120) (1)
Conserved Domains
A/G-specific adenine glycosylase [Streptococcus agalactiae]
A/G-specific adenine glycosylase [Streptococcus agalactiae]
gi|2643420567|ref|WP_323128217.1|

Protein
Carpophyllum maschalocarpum ribulose-1,5-bisphosphate carboxylase/oxygenase larg...
Carpophyllum maschalocarpum ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit (rbcL) gene, partial cds; rbcL-rbcS intergenic spacer, complete sequence; and ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit (rbcS) gene, partial cds; plastid
gi|399143610|gb|JN637977.1|

Nucleotide

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