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Select item 79570581.

Thymic Epithelial Cell-Derived IL-15 and IL-15 Receptor α Chain Foster Local Environment for Type 1 Innate Like T Cell Development

Huishan Tao, Lei Li, Nan-Shih Liao, Kimberly S. Schluns, Shirley Luckhart, John W. Sleasman, Xiao-Ping Zhong

Front Immunol. 2021; 12: 623280. Published online 2021 Mar 1. doi: 10.3389/fimmu.2021.623280

PMCID:: PMC7957058

Abstract Article PDF–3.5M

Select item 73908292.

IL-15 and IL15RA in Osteoarthritis: Association With Symptoms and Protease Production, but Not Structural Severity

Sophie C. Warner, Anjali Nair, Rahul Marpadga, Susan Chubinskaya, Michael Doherty, Ana M. Valdes, Carla R. Scanzello

Front Immunol. 2020; 11: 1385. Published online 2020 Jul 23. doi: 10.3389/fimmu.2020.01385

PMCID:: PMC7390829

Abstract Article PDF–2.4M

Select item 72504823.

Secretion and Biological Activity of Short Signal Peptide IL-15 Is Chaperoned by IL-15 Receptor Alpha In Vivo

Cristina Bergamaschi, Rashmi Jalah, Viraj Kulkarni, Margherita Rosati, Gen-Mu Zhang, Candido Alicea, Andrei S. Zolotukhin, Barbara K. Felber, George N. Pavlakis

J Immunol. Author manuscript; available in PMC 2020 May 26.

Published in final edited form as: J Immunol. 2009 Sep 1; 183(5): 3064–3072. doi: 10.4049/jimmunol.0900693

PMCID:: PMC7250482

Abstract Article PDF–1.3M

Select item 69175094.

A nanoscale reorganization of the IL-15 receptor is triggered by NKG2D in a ligand-dependent manner

Štefan Bálint, Filipa B. Lopes, Daniel M. Davis

Sci Signal. Author manuscript; available in PMC 2019 Dec 17.

Published in final edited form as: Sci Signal. 2018 Apr 10; 11(525): eaal3606. Published online 2018 Apr 10. doi: 10.1126/scisignal.aal3606

PMCID:: PMC6917509

Abstract Article PDF–4.0M

Select item 62215775.

Lung Dendritic Cells Drive Natural Killer Cytotoxicity in Chronic Obstructive Pulmonary Disease via IL-15Rα

Donna K. Finch, Valerie R. Stolberg, John Ferguson, Henrih Alikaj, Mohamed R. Kady, Bradley W. Richmond, Vasiliy V. Polosukhin, Timothy S. Blackwell, Lisa McCloskey, Jeffrey L. Curtis, Christine M. Freeman

Am J Respir Crit Care Med. 2018 Nov 1; 198(9): 1140–1150. Published online 2018 Nov 1. doi: 10.1164/rccm.201712-2513OC

PMCID:: PMC6221577

Abstract Article PDF–1.0M

Select item 61710746.

Superagonist IL-15-Armed Oncolytic Virus Elicits Potent Antitumor Immunity and Therapy That Are Enhanced with PD-1 Blockade

Stacy J. Kowalsky, Zuqiang Liu, Mathilde Feist, Sara E. Berkey, Congrong Ma, Roshni Ravindranathan, Enyong Dai, Edward J. Roy, Zong Sheng Guo, David L. Bartlett

Mol Ther. 2018 Oct 3; 26(10): 2476–2486. Published online 2018 Jul 17. doi: 10.1016/j.ymthe.2018.07.013

PMCID:: PMC6171074

Abstract Article PDF–1.7M

Select item 60144397.

A genetic variant in IL‐15Rα correlates with physical activity among European–American adults

Michael Bruneau, Jr, Sean Walsh, Eric Selinsky, Garrett Ash, Theodore J. Angelopoulos, Priscilla Clarkson, Paul Gordon, Niall Moyna, Paul Visich, Robert Zoeller, Paul Thompson, Heather Gordish‐Dressman, Eric Hoffman, Joseph Devaney, Linda S. Pescatello

Mol Genet Genomic Med. 2018 May; 6(3): 401–408. Published online 2018 Apr 6. doi: 10.1002/mgg3.368

PMCID:: PMC6014439

Abstract Article PDF–933K

Select item 53173498.

From Anabolic to Oxidative: Reconsidering the Roles of IL-15 and IL-15Rα in Skeletal Muscle

Emidio E. Pistilli, LeBris S. Quinn

Exerc Sport Sci Rev. Author manuscript; available in PMC 2017 Feb 20.

Published in final edited form as: Exerc Sport Sci Rev. 2013 Apr; 41(2): 100–106. doi: 10.1097/JES.0b013e318275d230

PMCID:: PMC5317349

Abstract Article PDF–725K

Select item 50545699.

Soluble and membrane‐bound interleukin (IL)‐15 Rα/IL‐15 complexes mediate proliferation of high‐avidity central memory CD8⁺ T cells for adoptive immunotherapy of cancer and infections

A. N. Hasan, A. Selvakumar, E. Shabrova, X.‐R. Liu, F. Afridi, G. Heller, I. Riviere, M. Sadelain, B. Dupont, R. J. O'Reilly

Clin Exp Immunol. 2016 Nov; 186(2): 249–265. Published online 2016 Aug 31. doi: 10.1111/cei.12816

PMCID:: PMC5054569

Abstract Article PDF–1.7M

Select item 486146210.

Configuration-dependent Presentation of Multivalent IL-15:IL-15Rα Enhances the Antigen-specific T Cell Response and Anti-tumor Immunity

Enping Hong, Ilana M. Usiskin, Cristina Bergamaschi, Douglas J. Hanlon, Richard L. Edelson, Sune Justesen, George N. Pavlakis, Richard A. Flavell, Tarek M. Fahmy

J Biol Chem. 2016 Apr 22; 291(17): 8931–8950. Published online 2015 Dec 30. doi: 10.1074/jbc.M115.695304

PMCID:: PMC4861462

Abstract Article PDF–3.7M

Select item 479254611.

Transpresentation of interleukin-15 by IL-15/IL-15Rα mRNA-engineered human dendritic cells boosts antitumoral natural killer cell activity

Johan Van den Bergh, Yannick Willemen, Eva Lion, Heleen Van Acker, Hans De Reu, Sébastien Anguille, Herman Goossens, Zwi Berneman, Viggo Van Tendeloo, Evelien Smits

Oncotarget. 2015 Dec 29; 6(42): 44123–44133. Published online 2015 Dec 9. doi: 10.18632/oncotarget.6536

PMCID:: PMC4792546

Abstract Article PDF–1.1M

Select item 460899712.

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef

Nicholas J. Matheson, Jonathan Sumner, Kim Wals, Radu Rapiteanu, Michael P. Weekes, Raphael Vigan, Julia Weinelt, Michael Schindler, Robin Antrobus, Ana S.H. Costa, Christian Frezza, Clary B. Clish, Stuart J.D. Neil, Paul J. Lehner

Cell Host Microbe. 2015 Oct 14; 18(4): 409–423. doi: 10.1016/j.chom.2015.09.003

PMCID:: PMC4608997

Abstract Article PDF–3.8M

Select item 445843213.

IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα production

Shinichiro Yokota, Osamu Yoshida, Lei Dou, Anthony V. Spadaro, Kumiko Isse, Mark A. Ross, Donna B. Stolz, Shoko Kimura, Qiang Du, Anthony J. Demetris, Angus W. Thomson, David A. Geller

J Immunol. Author manuscript; available in PMC 2016 Jun 15.

Published in final edited form as: J Immunol. 2015 Jun 15; 194(12): 6045–6056. Published online 2015 May 11. doi: 10.4049/jimmunol.1402505

PMCID:: PMC4458432

Abstract Article PDF–2.0M

Select item 435951114.

Differential expression of pro-inflammatory cytokines IL-15Ralpha, IL-15, IL-6 and TNFalpha in synovial fluid from Rheumatoid arthritis patients

Alicia Santos Savio, Ana Cecilia Machado Diaz, Araceli Chico Capote, Jamilet Miranda Navarro, Yunier Rodríguez Alvarez, Ricardo Bringas Pérez, Miguel Estévez del Toro, Gerardo E Guillen Nieto

BMC Musculoskelet Disord. 2015; 16: 51. Published online 2015 Mar 12. doi: 10.1186/s12891-015-0516-3

PMCID:: PMC4359511

Abstract Article PDF–796K

Select item 423905515.

NK Cell Activation in Human Hantavirus Infection Explained by Virus-Induced IL-15/IL15Rα Expression

Monika Braun, Niklas K. Björkström, Shawon Gupta, Karin Sundström, Clas Ahlm, Jonas Klingström, Hans-Gustaf Ljunggren

PLoS Pathog. 2014 Nov; 10(11): e1004521. Published online 2014 Nov 20. doi: 10.1371/journal.ppat.1004521

PMCID:: PMC4239055

Abstract Article PDF–1.3M

Select item 423269416.

Association between single nucleotide polymorphism of IL15RA gene with susceptibility to ossification of the posterior longitudinal ligament of the spine

Qiang Guo, Shou-Zheng Lv, Shu-Wen Wu, Xu Tian, Zhi-Yong Li

J Orthop Surg Res. 2014; 9: 103. Published online 2014 Nov 12. doi: 10.1186/s13018-014-0103-6

PMCID:: PMC4232694

Abstract Article PDF–186K

Select item 415908817.

Cytokine and cytokine receptor genes of adaptive immune response are differentially associated with breast cancer risk in American women of African and European ancestry

Lei Quan, Zhihong Gong, Song Yao, Elisa V. Bandera, Gary Zirpoli, Helena Hwang, Michelle Roberts, Gregory Ciupak, Warren Davis, Lara Sucheston, Karen Pawlish, Dana H. Bovbjerg, Lina Jandorf, Citadel Cabasag, Jean-Gabriel Coignet, Christine B. Ambrosone, Chi-Chen Hong

Int J Cancer. Author manuscript; available in PMC 2015 Mar 15.

Published in final edited form as: Int J Cancer. 2014 Mar 15; 134(6): 1408–1421. Published online 2013 Oct 8. doi: 10.1002/ijc.28458

PMCID:: PMC4159088

Abstract Article PDF–133K

Select item 406071318.

IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells

Fella Tamzalit, Isabelle Barbieux, Ariane Plet, Julie Heim, Steven Nedellec, Sébastien Morisseau, Yannick Jacques, Erwan Mortier

Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23): 8565–8570. Published online 2014 May 27. doi: 10.1073/pnas.1405514111

PMCID:: PMC4060713

Abstract Article PDF–1017K

Select item 397643319.

Vaccination with Tumor Cells Expressing IL-15 and IL-15Ra Inhibit Murine Breast and Prostate Cancer

John C. Morris, Charmaine A. Ramlogan-Steel, Ping Yu, Brittany A. Black, Poonam Mannan, James P. Allison, Thomas A. Waldmann, Jason C. Steel

Gene Ther. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Gene Ther. 2014 Apr; 21(4): 393–401. Published online 2014 Feb 27. doi: 10.1038/gt.2014.10

PMCID:: PMC3976433

Abstract Article PDF–1.5M

Select item 394834920.

Interleukin-15 and Soluble Interleukin-15 Receptor α in Coronary Artery Disease Patients: Association with Epicardial Fat and Indices of Adipose Tissue Distribution

Elena Dozio, Alexis Elias Malavazos, Elena Vianello, Silvia Briganti, Giada Dogliotti, Francesco Bandera, Francesca Giacomazzi, Serenella Castelvecchio, Lorenzo Menicanti, Alexander Sigrüener, Gerd Schmitz, Massimiliano Marco Corsi Romanelli

PLoS One. 2014; 9(3): e90960. Published online 2014 Mar 6. doi: 10.1371/journal.pone.0090960

PMCID:: PMC3948349

Abstract Article PDF–1.1M

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