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Items: 1 to 20 of 25

1.
Mitigation of TDP-43 toxic phenotype by an RGNEF fragment in amyotrophic lateral sclerosis models
Cristian A Droppelmann, Danae Campos-Melo, Veronica Noches, Crystal McLellan, Robert Szabla, Taylor A Lyons, Hind Amzil, Benjamin Withers, Brianna Kaplanis, Kirti S Sonkar, Anne Simon, Emanuele Buratti, Murray Junop, Jamie M Kramer, Michael J Strong
Brain. 2024 Jun; 147(6): 2053–2068. Published online 2024 May 13. doi: 10.1093/brain/awae078
PMCID:
PMC11146434
AbstractArticlePDF–1.5M
2.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
3.
Expression of a RhoA-Specific Guanine Nucleotide Exchange Factor, p190RhoGEF, in Mouse Macrophages Negatively Affects M1 Polarization and Inflammatory Responses
So-Yeon Choi, Yu Ri Ahn, Eun-Bi Lee, Mi Jin Yu, Jong Ran Lee
Front Immunol. 2022; 13: 782475. Published online 2022 Mar 29. doi: 10.3389/fimmu.2022.782475
PMCID:
PMC9002135
AbstractArticlePDF–3.8M
4.
Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications
Antonieta L. Salguero, Maggie Chen, Aaron T. Balana, Nam Chu, Hanjie Jiang, Brad A. Palanski, Hwan Bae, Katharine M. Wright, Sara Nathan, Heng Zhu, Sandra B. Gabelli, Matthew R. Pratt, Philip A. Cole
ACS Chem Biol. Author manuscript; available in PMC 2022 Feb 23.
Published in final edited form as: ACS Chem Biol. 2022 Jan 21; 17(1): 68–76. Published online 2021 Dec 23. doi: 10.1021/acschembio.1c00632
PMCID:
PMC8864695
AbstractArticlePDF–1.1M
5.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
6.
Inclusion Formation and Toxicity of the ALS Protein RGNEF and Its Association with the Microtubule Network
Sonja E. Di Gregorio, Kathryn Volkening, Michael J. Strong, Martin L. Duennwald
Int J Mol Sci. 2020 Aug; 21(16): 5597. Published online 2020 Aug 5. doi: 10.3390/ijms21165597
PMCID:
PMC7460592
AbstractArticlePDF–9.7M
7.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
8.
Rgnef promotes ovarian tumor progression and confers protection from oxidative stress
Elizabeth G. Kleinschmidt, Nichol L. G. Miller, Duygu Ozmadenci, Isabelle Tancioni, Carlos Díaz Osterman, Allison M. Barrie, Kristin N. Taylor, Aaron Ye, Shulin Jiang, Denise C. Connolly, Dwayne G. Stupack, David D. Schlaepfer
Oncogene. Author manuscript; available in PMC 2020 May 27.
Published in final edited form as: Oncogene. 2019 Sep; 38(36): 6323–6337. Published online 2019 Jul 15. doi: 10.1038/s41388-019-0881-8
PMCID:
PMC7252434
AbstractArticlePDF–2.9M
9.
Circular RNA circRGNEF promotes bladder cancer progression via miR-548/KIF2C axis regulation
Chen Yang, Qiong Li, Xinan Chen, Zheyu Zhang, Zezhong Mou, Fangdie Ye, Shengming Jin, Xiang Jun, Feng Tang, Haowen Jiang
Aging (Albany NY) 2020 Apr 30; 12(8): 6865–6879. Published online 2020 Apr 19. doi: 10.18632/aging.103047
Correction in:
Aging (Albany NY). 2023 May 31; 15(10): 4563–4565.
PMCID:
PMC7202505
AbstractArticlePDF–2.1M
10.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
11.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
12.
Direct Regulation of p190RhoGEF by Activated Rho and Rac GTPases
Olugbenga Dada, Stephen Gutowski, Chad A. Brautigam, Zhe Chen, Paul C. Sternweis
J Struct Biol. Author manuscript; available in PMC 2019 Apr 1.
Published in final edited form as: J Struct Biol. 2018 Apr; 202(1): 13–24. Published online 2017 Nov 28. doi: 10.1016/j.jsb.2017.11.014
PMCID:
PMC5835413
AbstractArticlePDF–1.0M
13.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
14.
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell
Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8
PMCID:
PMC5630600
AbstractArticlePDF–2.3M
15.
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family
Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang
Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277
PMCID:
PMC5013315
AbstractArticlePDF–3.2M
16.
Gastrin-stimulated Gα13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells
Miriam Masià-Balagué, Ismael Izquierdo, Georgina Garrido, Arnau Cordomí, Laura Pérez-Benito, Nichol L. G. Miller, David D. Schlaepfer, Véronique Gigoux, Anna M. Aragay
J Biol Chem. 2015 Jun 12; 290(24): 15197–15209. Published online 2015 Apr 28. doi: 10.1074/jbc.M114.628164
PMCID:
PMC4463461
AbstractArticlePDF–3.0M
17.
A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis
Nicolas Greliche, Marine Germain, Jean-Charles Lambert, William Cohen, Marion Bertrand, Anne-Marie Dupuis, Luc Letenneur, Mark Lathrop, Philippe Amouyel, Pierre-Emmanuel Morange, David-Alexandre Trégouët
BMC Med Genet. 2013; 14: 36. Published online 2013 Mar 20. doi: 10.1186/1471-2350-14-36
PMCID:
PMC3607886
AbstractArticlePDF–191K
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Replication of Previous Genome-wide Association Studies of Bone Mineral Density in Premenopausal American Women
Shoji Ichikawa, Daniel L Koller, Leah R Padgett, Dongbing Lai, Siu L Hui, Munro Peacock, Tatiana Foroud, Michael J Econs
J Bone Miner Res. 2010 Aug; 25(8): 1821–1829. Published online 2010 Feb 8. doi: 10.1002/jbmr.62
PMCID:
PMC3153352
AbstractArticlePDF–371K
20.
Genetic predictors of fibrin D-dimer levels in healthy adults
Nicholas L. Smith, Jennifer E. Huffman, David P. Strachan, Jie Huang, Abbas Dehghan, Stella Trompet, Lorna M. Lopez, So-Youn Shin, Jens Baumert, Veronique Vitart, Joshua C. Bis, Sarah H. Wild, Ann Rumley, Qiong Yang, Andre G Uitterlinden, David. J. Stott, Gail Davies, Angela M. Carter, Barbara Thorand, Ozren Polašek, Barbara McKnight, Harry Campbell, Alicja R. Rudnicka, Ming-Huei Chen, Brendan M. Buckley, Sarah E. Harris, Frances M. K. Williams, Annette Peters, Drazen Pulanic, Thomas Lumley, Anton J.M. de Craen, David C. Liewald, Christian Gieger, Susan Campbell, Ian Ford, Alan J. Gow, Michelle Luciano, David J. Porteous, Xiuqing Guo, Naveed Sattar, Albert Tenesa, Mary Cushman, P. Eline Slagboom, Peter M. Visscher, Tim D. Spector, Thomas Illig, Igor Rudan, Edwin G. Bovill, Alan F. Wright, Wendy L. McArdle, Geoffrey Tofler, Albert Hofman, Rudi G.J. Westendorp, John M. Starr, Peter J. Grant, Mahir Karakas, Nicholas D. Hastie, Bruce M. Psaty, James F. Wilson, Gordon D. O. Lowe, Christopher J O’Donnell, Jacqueline CM Witteman, J. Wouter Jukema, Ian J. Deary, Nicole Soranzo, Wolfgang Koenig, Caroline Hayward
Circulation. Author manuscript; available in PMC 2011 Nov 1.
Published in final edited form as: Circulation. 2011 May 3; 123(17): 1864–1872. Published online 2011 Apr 18. doi: 10.1161/CIRCULATIONAHA.110.009480
PMCID:
PMC3095913
AbstractArticlePDF–355K

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