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Select item 111136111.

E3 ubiquitin ligase RNF13 involves spatial learning and assembly of the SNARE complex

Qiang Zhang, Yanfeng Li, Lei Zhang, Nan Yang, Jiao Meng, Pingping Zuo, Yong Zhang, Jie Chen, Li Wang, Xiang Gao, Dahai Zhu

Cell Mol Life Sci. 2013 Jan; 70(1): 153–165. Published online 2012 Aug 14. doi: 10.1007/s00018-012-1103-5

PMCID:: PMC11113611

Abstract Article PDF–888K

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 105093113.

KIAA0317 regulates SOCS1 stability to ameliorate colonic inflammation

Karina C. Lockwood, Travis B. Lear, Shristi Rajbhandari, Alison C. McKelvey, Sarah R. Dunn, Áine N. Boudreau, Yuan Liu, Bill B. Chen

FEBS J. Author manuscript; available in PMC 2023 Sep 28.

Published in final edited form as: FEBS J. 2023 Aug; 290(15): 3802–3811. Published online 2023 Apr 7. doi: 10.1111/febs.16780

PMCID:: PMC10509311

Abstract Article PDF–1.6M

Select item 103180114.

SIRT1 ubiquitination is regulated by opposing activities of APC/C-Cdh1 and AROS during stress-induced premature senescence

Sang Hyup Lee, Ji-Hye Yang, Ui-Hyun Park, Hanbyeul Choi, Yoo Sung Kim, Bo-Eun Yoon, Hye-Jeong Han, Hyun-Taek Kim, Soo-Jong Um, Eun-Joo Kim

Exp Mol Med. 2023 Jun; 55(6): 1232–1246. Published online 2023 Jun 1. doi: 10.1038/s12276-023-01012-1

PMCID:: PMC10318011

Abstract Article PDF–4.5M

Select item 102628115.

TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection

Jie Wang, Xiao Qin, Yulu Huang, Qunmei Zhang, Jinyong Pei, Yi Wang, Idan Goren, Shujun Ma, Zhishan Song, Yanzi Liu, Hongxia Xing, Hui Wang, Bo Yang

Autophagy. 2023; 19(6): 1844–1862. Published online 2023 Jan 1. doi: 10.1080/15548627.2022.2162706

PMCID:: PMC10262811

Abstract Article PDF–7.7M

Select item 102341076.

The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function

William R. Critchley, Gina A. Smith, Ian C. Zachary, Michael A. Harrison, Sreenivasan Ponnambalam

J Cell Sci. 2023 May 15; 136(10): jcs260657. Published online 2023 May 25. doi: 10.1242/jcs.260657

PMCID:: PMC10234107

Abstract Article

Select item 102042937.

S100A6 inhibits MDM2 to suppress breast cancer growth and enhance sensitivity to chemotherapy

Mengxin Qi, Xianglan Yi, Baohui Yue, Mingxiang Huang, Sheng Zhou, Jing Xiong

Breast Cancer Res. 2023; 25: 55. Published online 2023 May 22. doi: 10.1186/s13058-023-01657-w

PMCID:: PMC10204293

Abstract Article PDF–10M

Select item 100809088.

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy

BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4

PMCID:: PMC10080908

Abstract Article PDF–3.2M

Select item 100704389.

E3 ligase RNF99 negatively regulates TLR-mediated inflammatory immune response via K48-linked ubiquitination of TAB2

Jie Zhang, Lei Cao, Amy Gao, Ruiqing Ren, Liwen Yu, Qian Li, Yapeng Liu, Wenqian Qi, Yonghao Hou, Wenhai Sui, Guohai Su, Yun Zhang, Cheng Zhang, Meng Zhang

Cell Death Differ. 2023 Apr; 30(4): 966–978. Published online 2023 Jan 21. doi: 10.1038/s41418-023-01115-2

PMCID:: PMC10070438

Abstract Article PDF–11M

Select item 1003393710.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 995044611.

SPOP mutations promote tumor immune escape in endometrial cancer via the IRF1–PD-L1 axis

Kun Gao, Qing Shi, Ye Gu, Wanqi Yang, Yuanlong He, Zeheng Lv, Yan Ding, Wenxin Cao, Chenji Wang, Xiaoping Wan

Cell Death Differ. 2023 Feb; 30(2): 475–487. Published online 2022 Dec 8. doi: 10.1038/s41418-022-01097-7

PMCID:: PMC9950446

Abstract Article PDF–4.9M

Select item 988839312.

PD-L1 translocation to the plasma membrane enables tumor immune evasion through MIB2 ubiquitination

Xinfang Yu, Wei Li, Haidan Liu, Xu Wang, Cristian Coarfa, Chao Cheng, Xinlian Yu, Zhaoyang Zeng, Ya Cao, Ken H. Young, Yong Li

J Clin Invest. 2023 Feb 1; 133(3): e160456. Published online 2023 Feb 1. doi: 10.1172/JCI160456

PMCID:: PMC9888393

Abstract Article PDF–5.0M

Select item 988326113.

Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor

Seung Un Seo, Seon Min Woo, Min Wook Kim, Eun-Woo Lee, Kyoung-jin Min, Taeg Kyu Kwon

Cell Death Differ. 2023 Jan; 30(1): 82–93. Published online 2022 Aug 4. doi: 10.1038/s41418-022-01047-3

PMCID:: PMC9883261

Abstract Article PDF–4.6M

Select item 986049614.

Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method

Ryota Hayashida, Reika Kikuchi, Kenichiro Imai, Waka Kojima, Tatsuya Yamada, Miho Iijima, Hiromi Sesaki, Keiji Tanaka, Noriyuki Matsuda, Koji Yamano

J Biol Chem. 2023 Feb; 299(2): 102822. Published online 2022 Dec 21. doi: 10.1016/j.jbc.2022.102822

PMCID:: PMC9860496

Abstract Article PDF–6.6M

Select item 980513415.

SPOP inhibits BRAF-dependent tumorigenesis through promoting non-degradative ubiquitination of BRAF

Kai Feng, Qing Shi, Dongyue Jiao, Yingji Chen, Wanqi Yang, Ke Su, Yalan Wang, Yan Huang, Pingzhao Zhang, Yao Li, Chenji Wang

Cell Biosci. 2022; 12: 211. Published online 2022 Dec 30. doi: 10.1186/s13578-022-00950-z

PMCID:: PMC9805134

Abstract Article PDF–9.4M

Select item 973205116.

Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity

Diego Esposito, Jane Dudley-Fraser, Acely Garza-Garcia, Katrin Rittinger

Nat Commun. 2022; 13: 7583. Published online 2022 Dec 8. doi: 10.1038/s41467-022-35300-7

PMCID:: PMC9732051

Abstract Article PDF–4.5M

Select item 950846917.

Protocol to detect in vitro and in cell ubiquitylation of mitochondrial DNA polymerase gamma by mitochondrial E3 ligase MITOL

Mansoor Hussain, Shabnam Saifi, Aftab Mohammed, Sagar Sengupta

STAR Protoc. 2022 Dec 16; 3(4): 101710. Published online 2022 Sep 21. doi: 10.1016/j.xpro.2022.101710

PMCID:: PMC9508469

Abstract Article PDF–1.7M

Select item 943681418.

Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia

Haixia Zhuang, Ying Ren, Chenyu Mao, Yueya Zhong, Zubin Zhang, Biyin Cao, Yuming Zhang, Jinqi Huang, Guoqiang Xu, Zhenqian Huang, Yujia Xu, Xinliang Mao

J Biol Chem. 2022 Sep; 298(9): 102314. Published online 2022 Aug 1. doi: 10.1016/j.jbc.2022.102314

PMCID:: PMC9436814

Abstract Article PDF–3.8M

Select item 936528819.

Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy

Xiao-Wen Zhang, Na Feng, Yan-Chen Liu, Qiang Guo, Jing-Kang Wang, Yi-Zhen Bai, Xiao-Ming Ye, Zhuo Yang, Heng Yang, Yang Liu, Mi-Mi Yang, Yan-Hang Wang, Xiao-Meng Shi, Dan Liu, Peng-Fei Tu, Ke-Wu Zeng

Sci Adv. 2022 Aug; 8(31): eabo0789. Published online 2022 Aug 10. doi: 10.1126/sciadv.abo0789

PMCID:: PMC9365288

Abstract Article PDF–16M

Select item 930062620.

The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling

Xiaomin Ma, Xiaoxiao Ma, Lihui Zhu, Yunxue Zhao, Mengmeng Chen, Tao Li, Yueke Lin, Dapeng Ma, Caiyu Sun, Lihui Han

Oncogenesis. 2022 Dec; 11(1): 40. Published online 2022 Jul 20. doi: 10.1038/s41389-022-00414-6

PMCID:: PMC9300626

Abstract Article PDF–4.2M

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