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Select item 92626141.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 83642002.

Proteolytic processing of secretory pathway kinase Fam20C by site-1 protease promotes biomineralization

Xinxin Chen, Jianchao Zhang, Pulan Liu, Yangyang Wei, Xi’e Wang, Junyu Xiao, Chih-chen Wang, Lei Wang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2100133118. Published online 2021 Aug 4. doi: 10.1073/pnas.2100133118

PMCID:: PMC8364200

Abstract Article PDF–2.5M

Select item 83487773.

FAM20C Overview: Classic and Novel Targets, Pathogenic Variants and Raine Syndrome Phenotypes

Icela Palma-Lara, Monserrat Pérez-Ramírez, Patricia García Alonso-Themann, Ana María Espinosa-García, Ricardo Godinez-Aguilar, José Bonilla-Delgado, Adolfo López-Ornelas, Georgina Victoria-Acosta, María Guadalupe Olguín-García, José Moreno, Carmen Palacios-Reyes

Int J Mol Sci. 2021 Aug; 22(15): 8039. Published online 2021 Jul 27. doi: 10.3390/ijms22158039

PMCID:: PMC8348777

Abstract Article PDF–3.3M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79489685.

The ABCs of the atypical Fam20 secretory pathway kinases

Carolyn A. Worby, Joshua E. Mayfield, Adam J. Pollak, Jack E. Dixon, Sourav Banerjee

J Biol Chem. 2021 Jan-Jun; 296: 100267. Published online 2021 Jan 8. doi: 10.1016/j.jbc.2021.100267

PMCID:: PMC7948968

Abstract Article PDF–3.3M

Select item 77863346.

Prognostic and immunological role of Fam20C in pan-cancer

Xinpeng Liu, Yuanbo Zhan, Wenxia Xu, Xiaoyao Liu, Yawei Geng, Lixue Liu, Junlong Da, Jianqun Wang, Xinjian Zhang, Han jin, Zhongshuang Liu, Shouli Guo, Bin Zhang, Ying Li

Biosci Rep. 2021 Jan 29; 41(1): BSR20201920. Published online 2021 Jan 5. doi: 10.1042/BSR20201920

PMCID:: PMC7786334

Abstract Article PDF–2.2M

Select item 76903667.

Adult diffuse glioma GWAS by molecular subtype identifies variants in D2HGDH and FAM20C

Jeanette E Eckel-Passow, Kristen L Drucker, Thomas M Kollmeyer, Matt L Kosel, Paul A Decker, Annette M Molinaro, Terri Rice, Corinne E Praska, Lauren Clark, Alissa Caron, Alexej Abyzov, Anthony Batzler, Jun S Song, Melike Pekmezci, Helen M Hansen, Lucie S McCoy, Paige M Bracci, Joseph Wiemels, John K Wiencke, Stephen Francis, Terry C Burns, Caterina Giannini, Daniel H Lachance, Margaret Wrensch, Robert B Jenkins

Neuro Oncol. 2020 Nov; 22(11): 1602–1613. Published online 2020 May 9. doi: 10.1093/neuonc/noaa117

PMCID:: PMC7690366

Abstract Article PDF–9.5M

Select item 75555508.

FAM20C directly binds to and phosphorylates Periostin

Ju-Hsien Lin, I-Ping Lin, Yoshio Ohyama, Hanna Mochida, Akira Kudo, Masaru Kaku, Yoshiyuki Mochida

Sci Rep. 2020; 10: 17155. Published online 2020 Oct 13. doi: 10.1038/s41598-020-74400-6

PMCID:: PMC7555550

Abstract Article PDF–2.3M

Select item 74949899.

Ras-transformation reduce FAM20C expression and osteopontin phosphorylation

Gitte N. Schytte, Brian Christensen, Ida Bregenov, Esben S. Sørensen

Biosci Rep. 2020 Sep 30; 40(9): BSR20194378. Published online 2020 Sep 16. doi: 10.1042/BSR20194378

PMCID:: PMC7494989

Abstract Article PDF–662K

Select item 732206710.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 726533111.

Fam20C regulates protein secretion by Cab45 phosphorylation

Tobias Karl-Heinz Hecht, Birgit Blank, Martin Steger, Victor Lopez, Gisela Beck, Bulat Ramazanov, Matthias Mann, Vincent Tagliabracci, Julia von Blume

J Cell Biol. 2020 Jun 1; 219(6): e201910089. Published online 2020 May 18. doi: 10.1083/jcb.201910089

PMCID:: PMC7265331

Abstract Article PDF–6.4M

Select item 723200912.

Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress

Jiaojiao Yu, Tao Li, Yu Liu, Xi Wang, Jianchao Zhang, Xi'e Wang, Guizhi Shi, Jizhong Lou, Likun Wang, Chih‐chen Wang, Lei Wang

EMBO J. 2020 May 18; 39(10): e103841. Published online 2020 Mar 9. doi: 10.15252/embj.2019103841

PMCID:: PMC7232009

Abstract Article PDF–5.5M

Select item 707352313.

Two Novel FAM20C Variants in a Family with Raine Syndrome

Araceli Hernández-Zavala, Fernando Cortés-Camacho, Icela Palma-Lara, Ricardo Godínez-Aguilar, Ana María Espinosa, Javier Pérez-Durán, Patricia Villanueva-Ocampo, Carlos Ugarte-Briones, Carlos Alberto Serrano-Bello, Paula Jesús Sánchez-Santiago, José Bonilla-Delgado, Marco Antonio Yáñez-López, Georgina Victoria-Acosta, Adolfo López-Ornelas, Patricia García Alonso-Themann, José Moreno, Carmen Palacios-Reyes

Genes (Basel) 2020 Feb; 11(2): 222. Published online 2020 Feb 20. doi: 10.3390/genes11020222

PMCID:: PMC7073523

Abstract Article PDF–5.3M

Select item 654512614.

In vitro phosphorylation of von Willebrand factor by FAM20c enhances its ability to support platelet adhesion.

Qi Da, Hyojeong Han, Christian Valladolid, María Fernández, Tanvir Khatlani, Subhashree Pradhan, Jennifer Nolasco, Risë K. Matsunami, David A Engler, Miguel A. Cruz, K. Vinod Vijayan

J Thromb Haemost. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: J Thromb Haemost. 2019 Jun; 17(6): 866–877. Published online 2019 Apr 5. doi: 10.1111/jth.14426

PMCID:: PMC6545126

Abstract Article PDF–1.3M

Select item 652888415.

FAM20C could be targeted by TET1 to promote odontoblastic differentiation potential of human dental pulp cells

Qimeng Li, Baicheng Yi, Zhihui Feng, Runsha Meng, Cheng Tian, Qiong Xu

Cell Prolif. 2018 Apr; 51(2): e12426. Published online 2017 Dec 25. doi: 10.1111/cpr.12426

PMCID:: PMC6528884

Abstract Article PDF–993K

Select item 629825416.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 616668217.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 607772218.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 604384919.

Secretory kinase Fam20C tunes endoplasmic reticulum redox state via phosphorylation of Ero1α

Jianchao Zhang, Qinyu Zhu, Xi'e Wang, Jiaojiao Yu, Xinxin Chen, Jifeng Wang, Xi Wang, Junyu Xiao, Chih‐chen Wang, Lei Wang

EMBO J. 2018 Jul 13; 37(14): e98699. Published online 2018 Jun 1. doi: 10.15252/embj.201798699

PMCID:: PMC6043849

Abstract Article PDF–4.5M

Select item 594882020.

A case of Raine syndrome presenting with facial dysmorphy and review of literature

Jayesh Sheth, Riddhi Bhavsar, Ajit Gandhi, Frenny Sheth, Dhairya Pancholi

BMC Med Genet. 2018; 19: 76. Published online 2018 May 11. doi: 10.1186/s12881-018-0593-x

PMCID:: PMC5948820

Abstract Article PDF–3.1M

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