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Select item 100471491.

Genomic Redistribution of Metal-Response Transcription Factor-1 (MTF-1) in Cadmium Resistant Cells

Gregory M. Wright, Joshua C. Black

Cells. 2023 Mar; 12(6): 953. Published online 2023 Mar 21. doi: 10.3390/cells12060953

PMCID:: PMC10047149

Abstract Article PDF–2.4M

Select item 90229442.

The Hippo pathway kinases LATS1 and 2 attenuate cellular responses to heavy metals through phosphorylating MTF1

Han Han, Hiroki J Nakaoka, Line Hofmann, Jeff Jiajing Zhou, Clinton Yu, Lisha Zeng, Junyu Nan, Gayoung Seo, Rebecca Elizabeth Vargas, Bing Yang, Ruxi Qi, Lee Bardwell, Dmitry A. Fishman, Ken W.Y. Cho, Lan Huang, Ray Luo, Rahul Warrior, Wenqi Wang

Nat Cell Biol. Author manuscript; available in PMC 2022 Jul 13.

Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 74–87. Published online 2022 Jan 13. doi: 10.1038/s41556-021-00813-8

PMCID:: PMC9022944

Abstract Article PDF–8.9M

Select item 80090483.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 75668814.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 58391585.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells

Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo

Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31

PMCID:: PMC5839158

Abstract Article PDF–1.9M

Select item 58269266.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 57681507.

MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4B^DCAF13 E3 Ligase in Osteosarcoma Cells

Zhi Chen, Wei Zhang, Kaibiao Jiang, Bin Chen, Kun Wang, Lifeng Lao, Canglong Hou, Fei Wang, Caiguo Zhang, Hongxing Shen

Mol Ther Nucleic Acids. 2018 Mar 2; 10: 254–268. Published online 2017 Dec 22. doi: 10.1016/j.omtn.2017.12.010

PMCID:: PMC5768150

Abstract Article PDF–2.7M

Select item 54581748.

Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation

Shalaka Chitale, Holger Richly

Oncotarget. 2017 May 9; 8(19): 30870–30887. Published online 2017 Mar 11. doi: 10.18632/oncotarget.16142

PMCID:: PMC5458174

Abstract Article PDF–6.0M

Select item 46892939.

Genetic variation in metallothionein and metal-regulatory transcription factor 1 in relation to urinary cadmium, copper, and zinc

Scott V. Adams, Brian Barrick, Emily P. Freney, Martin M. Shafer, Karen Makar, Xiaoling Song, Johanna Lampe, Hugo Vilchis, April Ulery, Polly A. Newcomb

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2016 Dec 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2015 Dec 15; 289(3): 381–388. Published online 2015 Oct 31. doi: 10.1016/j.taap.2015.10.024

PMCID:: PMC4689293

Abstract Article PDF–723K

Select item 414654310.

Zn-Responsive Proteome Profiling and Time-Dependent Expression of Proteins Regulated by MTF-1 in A549 Cells

Wen-jie Zhao, Qun Song, Yan-hong Wang, Ke-jin Li, Li Mao, Xin Hu, Hong-zhen Lian, Wei-juan Zheng, Zi-chun Hua

PLoS One. 2014; 9(8): e105797. Published online 2014 Aug 27. doi: 10.1371/journal.pone.0105797

PMCID:: PMC4146543

Abstract Article PDF–2.1M

Select item 394409811.

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Yukinori Okada, Di Wu, Gosia Trynka, Towfique Raj, Chikashi Terao, Katsunori Ikari, Yuta Kochi, Koichiro Ohmura, Akari Suzuki, Shinji Yoshida, Robert R. Graham, Arun Manoharan, Ward Ortmann, Tushar Bhangale, Joshua C. Denny, Robert J. Carroll, Anne E. Eyler, Jeffrey D. Greenberg, Joel M. Kremer, Dimitrios A. Pappas, Lei Jiang, Jian Yin, Lingying Ye, Ding-Feng Su, Jian Yang, Gang Xie, Ed Keystone, Harm-Jan Westra, Tõnu Esko, Andres Metspalu, Xuezhong Zhou, Namrata Gupta, Daniel Mirel, Eli A. Stahl, Dorothée Diogo, Jing Cui, Katherine Liao, Michael H. Guo, Keiko Myouzen, Takahisa Kawaguchi, Marieke J.H. Coenen, Piet L.C.M. van Riel, Mart A.F.J. van de Laar, Henk-Jan Guchelaar, Tom W.J. Huizinga, Philippe Dieudé, Xavier Mariette, S. Louis Bridges, Jr., Alexandra Zhernakova, Rene E.M. Toes, Paul P. Tak, Corinne Miceli-Richard, So-Young Bang, Hye-Soon Lee, Javier Martin, Miguel A. Gonzalez-Gay, Luis Rodriguez-Rodriguez, Solbritt Rantapää-Dahlqvist, Lisbeth Ärlestig, Hyon K. Choi, Yoichiro Kamatani, Pilar Galan, Mark Lathrop, the RACI consortium, the GARNET consortium, Steve Eyre, John Bowes, Anne Barton, Niek de Vries, Larry W. Moreland, Lindsey A. Criswell, Elizabeth W. Karlson, Atsuo Taniguchi, Ryo Yamada, Michiaki Kubo, Jun S. Liu, Sang-Cheol Bae, Jane Worthington, Leonid Padyukov, Lars Klareskog, Peter K. Gregersen, Soumya Raychaudhuri, Barbara E. Stranger, Philip L. De Jager, Lude Franke, Peter M. Visscher, Matthew A. Brown, Hisashi Yamanaka, Tsuneyo Mimori, Atsushi Takahashi, Huji Xu, Timothy W. Behrens, Katherine A. Siminovitch, Shigeki Momohara, Fumihiko Matsuda, Kazuhiko Yamamoto, Robert M. Plenge

Nature. Author manuscript; available in PMC 2014 Aug 20.

Published in final edited form as: Nature. 2014 Feb 20; 506(7488): 376–381. Published online 2013 Dec 25. doi: 10.1038/nature12873

PMCID:: PMC3944098

Abstract Article PDF–1.9M

Select item 365454612.

Zinc-Dependent Lysosomal Enlargement in TRPML1-Deficient Cells Involves MTF-1 Transcription Factor and ZnT4 (Slc30a4) Transporter

Ira Kukic, Jeffrey K. Lee, Jessica Coblentz, Shannon L. Kelleher, Kirill Kiselyov

Biochem J. Author manuscript; available in PMC 2013 May 15.

Published in final edited form as: Biochem J. 2013 Apr 15; 451(2): 155–163. doi: 10.1042/BJ20121506

PMCID:: PMC3654546

Abstract Article PDF–4.1M

Select item 332102313.

Novel Associations for Hypothyroidism Include Known Autoimmune Risk Loci

Nicholas Eriksson, Joyce Y. Tung, Amy K. Kiefer, David A. Hinds, Uta Francke, Joanna L. Mountain, Chuong B. Do

PLoS One. 2012; 7(4): e34442. Published online 2012 Apr 6. doi: 10.1371/journal.pone.0034442

PMCID:: PMC3321023

Abstract Article PDF–750K

Select item 323485314.

The Role of Small Ubiquitin-like Modifier-interacting Motif in the Assembly and Regulation of Metal-responsive Transcription Factor 1

Ya-Chuan Liu, Meng-Chieh Lin, Hsiang-Chi Chen, Ming F. Tam, Lih-Yuan Lin

J Biol Chem. 2011 Dec 16; 286(50): 42818–42829. Published online 2011 Oct 22. doi: 10.1074/jbc.M111.253203

PMCID:: PMC3234853

Abstract Article PDF–1.7M

Select item 320617615.

LACK OF ASSOCIATION BETWEEN AUTISM AND FOUR HEAVY METAL REGULATORY GENES

Sarah E. Owens, Marshall L. Summar, Kelli K. Ryckman, Jonathan L. Haines, Sara Reiss, Samantha R. Summar, Michael Aschner

Neurotoxicology. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Neurotoxicology. 2011 Dec; 32(6): 769–775. Published online 2011 Jul 20. doi: 10.1016/j.neuro.2011.07.003

PMCID:: PMC3206176

Abstract Article PDF–94K

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 304623917.

Transcriptional Regulation of the Beta-Synuclein 5′-Promoter Metal Response Element by Metal Transcription Factor-1

Patrick C. McHugh, Josephine A. Wright, David R. Brown

PLoS One. 2011; 6(2): e17354. Published online 2011 Feb 28. doi: 10.1371/journal.pone.0017354

PMCID:: PMC3046239

Abstract Article PDF–283K

Select item 299612118.

Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux

Marie-Berengere Troadec, Diane McVey Ward, Eric Lo, Jerry Kaplan, Ivana De Domenico

Blood. 2010 Nov 25; 116(22): 4657–4664. Prepublished online 2010 Aug 5. doi: 10.1182/blood-2010-04-278614

PMCID:: PMC2996121

Abstract Article

Select item 287256119.

An empirical framework for binary interactome mapping

Kavitha Venkatesan, Jean-François Rual, Alexei Vazquez, Ulrich Stelzl, Irma Lemmens, Tomoko Hirozane-Kishikawa, Tong Hao, Martina Zenkner, Xiaofeng Xin, Kwang-II Goh, Muhammed A Yildirim, Nicolas Simonis, Kathrin Heinzmann, Fana Gebreab, Julie M Sahalie, Sebiha Cevik, Christophe Simon, Anne-Sophie de Smet, Elizabeth Dann, Alex Smolyar, Arunachalam Vinayagam, Haiyuan Yu, David Szeto, Heather Borick, Amélie Dricot, Niels Klitgord, Ryan R Murray, Chenwei Lin, Maciej Lalowski, Jan Timm, Kirstin Rau, Charles Boone, Pascal Braun, Michael E Cusick, Frederick P Roth, David E Hill, Jan Tavernier, Erich E Wanker, Albert-László Barabási, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2010 May 18.

Published in final edited form as: Nat Methods. 2009 Jan; 6(1): 83–90. Published online 2008 Dec 7. doi: 10.1038/nmeth.1280

PMCID:: PMC2872561

Abstract Article PDF–1.0M

Select item 282658620.

Metal transcription factor-1 regulation via MREs in the transcribed regions of selenoprotein H and other metal- responsive genes

Zoia R. Stoytcheva, Vladimir Vladimirov, Vanessa Douet, Ilko Stoychev, Marla J. Berry

Biochim Biophys Acta. Author manuscript; available in PMC 2011 Mar 1.

Published in final edited form as: Biochim Biophys Acta. 2010 Mar; 1800(3): 416–424. Published online 2009 Nov 12. doi: 10.1016/j.bbagen.2009.11.003

PMCID:: PMC2826586

Abstract Article PDF–1.2M

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