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Select item 97101801.

A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension

Xiao Xiao, Rui Li, Cunjin Wu, Yupeng Yan, Mengmeng Yuan, Bing Cui, Yu Zhang, Channa Zhang, Xiaoxia Zhang, Weili Zhang, Rutai Hui, Yibo Wang

BMC Med. 2022; 20: 463. Published online 2022 Nov 30. doi: 10.1186/s12916-022-02665-x

Correction in:: BMC Med. 2022; 20: 491.

PMCID:: PMC9710180

Abstract Article PDF–2.6M

Select item 91452882.

The Cell Surface Heparan Sulfate Proteoglycan Syndecan-3 Promotes Ovarian Cancer Pathogenesis

Lara Hillemeyer, Nancy Adriana Espinoza-Sanchez, Burkhard Greve, Nourhan Hassan, Anca Chelariu-Raicu, Ludwig Kiesel, Martin Götte

Int J Mol Sci. 2022 May; 23(10): 5793. Published online 2022 May 21. doi: 10.3390/ijms23105793

PMCID:: PMC9145288

Abstract Article PDF–3.0M

Select item 91197363.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 88570494.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 83954745.

Syndecan Family Gene and Protein Expression and Their Prognostic Values for Prostate Cancer

Nilton José Santos, Caroline Nascimento Barquilha, Isabela Correa Barbosa, Rodrigo Tavares Macedo, Flávio Oliveira Lima, Luis Antônio Justulin, Guilherme Oliveira Barbosa, Hernandes F. Carvalho, Sérgio Luis Felisbino

Int J Mol Sci. 2021 Aug; 22(16): 8669. Published online 2021 Aug 12. doi: 10.3390/ijms22168669

PMCID:: PMC8395474

Abstract Article PDF–4.0M

Select item 82680556.

The Interplay of Apoes with Syndecans in Influencing Key Cellular Events of Amyloid Pathology

Anett Hudák, Katalin Jósvay, Ildikó Domonkos, Annamária Letoha, László Szilák, Tamás Letoha

Int J Mol Sci. 2021 Jul; 22(13): 7070. Published online 2021 Jun 30. doi: 10.3390/ijms22137070

PMCID:: PMC8268055

Abstract Article PDF–7.0M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81590908.

Contribution of Syndecans to the Cellular Entry of SARS-CoV-2

Anett Hudák, Annamária Letoha, László Szilák, Tamás Letoha

Int J Mol Sci. 2021 May; 22(10): 5336. Published online 2021 May 19. doi: 10.3390/ijms22105336

PMCID:: PMC8159090

Abstract Article PDF–11M

Select item 79936829.

LncRNA TRPM2-AS promotes ovarian cancer progression and cisplatin resistance by sponging miR-138-5p to release SDC3 mRNA

Yi Ding, Xiangyu Tan, Abuduyilimu Abasi, Yun Dai, Ruxing Wu, Tao Zhang, Kexin Li, Miao Yan, Xiaoyuan Huang

Aging (Albany NY) 2021 Mar 15; 13(5): 6832–6848. Published online 2021 Feb 17. doi: 10.18632/aging.202541

PMCID:: PMC7993682

Abstract Article PDF–2.0M

Select item 756140610.

Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment

Endika Prieto-Fernández, Leire Egia-Mendikute, Alexandre Bosch, Ana García del Río, Borja Jimenez-Lasheras, Asier Antoñana-Vildosola, So Young Lee, Asis Palazon

Front Immunol. 2020; 11: 586977. Published online 2020 Sep 30. doi: 10.3389/fimmu.2020.586977

PMCID:: PMC7561406

Abstract Article PDF–6.3M

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 685109812.

Contribution of syndecans to cellular uptake and fibrillation of α-synuclein and tau

Anett Hudák, Erzsébet Kusz, Ildikó Domonkos, Katalin Jósvay, Alpha Tom Kodamullil, László Szilák, Martin Hofmann-Apitius, Tamás Letoha

Sci Rep. 2019; 9: 16543. Published online 2019 Nov 12. doi: 10.1038/s41598-019-53038-z

PMCID:: PMC6851098

Abstract Article PDF–8.7M

Select item 678250013.

Regulated Expression and Subcellular Localization of Syndecan Heparan Sulfate Proteoglycans and the Syndecan-Binding Protein CASK/LIN-2 during Rat Brain Development

Yi-Ping Hsueh, Morgan Sheng

J Neurosci. 1999 Sep 1; 19(17): 7415–7425. doi: 10.1523/JNEUROSCI.19-17-07415.1999

PMCID:: PMC6782500

Abstract Article PDF–1.9M

Select item 662511814.

Soluble syndecan-3 binds chemokines, reduces leukocyte migration in vitro and ameliorates disease severity in models of rheumatoid arthritis

Andrew D. Eustace, Emily F. McNaughton, Sophie King, Oksana Kehoe, Andreas Kungl, Derek Mattey, Angela H. Nobbs, Neil Williams, Jim Middleton

Arthritis Res Ther. 2019; 21: 172. Published online 2019 Jul 12. doi: 10.1186/s13075-019-1939-2

PMCID:: PMC6625118

Abstract Article PDF–1.4M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549522516.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 546707717.

Pleiotrophin and N-syndecan promote perineural invasion and tumor progression in an orthotopic mouse model of pancreatic cancer

Jun Yao, Lu-Lin Zhang, Xu-Mei Huang, Wen-Yao Li, She-Gan Gao

World J Gastroenterol. 2017 Jun 7; 23(21): 3907–3914. Published online 2017 Jun 7. doi: 10.3748/wjg.v23.i21.3907

PMCID:: PMC5467077

Abstract Article PDF–1.1M

Select item 488219018.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 487287919.

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

Javier Barallobre-Barreiro, Rahmi Oklu, Marc Lynch, Marika Fava, Ferheen Baig, Xiaoke Yin, Temo Barwari, David N. Potier, Hassan Albadawi, Marjan Jahangiri, Karen E. Porter, Michael T. Watkins, Sanjay Misra, Julianne Stoughton, Manuel Mayr

Cardiovasc Res. 2016 Jun 1; 110(3): 419–430. Published online 2016 Apr 11. doi: 10.1093/cvr/cvw075

PMCID:: PMC4872879

Abstract Article PDF–1.1M

Select item 444121520.

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

Nidhi Sahni, Song Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe-Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios I. Karras, Yang Wang, István A. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy H. Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang-Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San-Miguel, Changyu Fan, Dawit Balcha, Amelie Dricot, Daniel M. Jordan, Jennifer M. Walsh, Akash A. Shah, Xinping Yang, Ani Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi-Ashtiani, Luke J. Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-László Barabási, Benoit Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal

Cell. Author manuscript; available in PMC 2016 Apr 23.

Published in final edited form as: Cell. 2015 Apr 23; 161(3): 647–660. doi: 10.1016/j.cell.2015.04.013

PMCID:: PMC4441215

Abstract Article PDF–1.2M

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