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Select item 107135331.

Mint3-depletion-induced energy stress sensitizes triple-negative breast cancer to chemotherapy via HSF1 inactivation

Noritaka Tanaka, Hikari Okada, Kiyoshi Yamaguchi, Masahide Seki, Daisuke Matsubara, Noriko Gotoh, Yutaka Suzuki, Yoichi Furukawa, Taro Yamashita, Jun-ichiro Inoue, Shuichi Kaneko, Takeharu Sakamoto

Cell Death Dis. 2023 Dec; 14(12): 815. Published online 2023 Dec 11. doi: 10.1038/s41419-023-06352-4

PMCID:: PMC10713533

Abstract Article PDF–7.5M

Select item 85710822.

Structural and thermodynamical insights into the binding and inhibition of FIH-1 by the N-terminal disordered region of Mint3

Tensho Ten, Satoru Nagatoishi, Ryo Maeda, Masaru Hoshino, Yoshiaki Nakayama, Motoharu Seiki, Takeharu Sakamoto, Kouhei Tsumoto

J Biol Chem. 2021 Nov; 297(5): 101304. Published online 2021 Oct 14. doi: 10.1016/j.jbc.2021.101304

PMCID:: PMC8571082

Abstract Article PDF–2.4M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75157984.

Mint3 depletion restricts tumor malignancy of pancreatic cancer cells by decreasing SKP2 expression via HIF-1

Akane Kanamori, Daisuke Matsubara, Yurika Saitoh, Yuya Fukui, Noriko Gotoh, Shuichi Kaneko, Motoharu Seiki, Yoshinori Murakami, Jun-ichiro Inoue, Takeharu Sakamoto

Oncogene. 2020; 39(39): 6218–6230. Published online 2020 Aug 21. doi: 10.1038/s41388-020-01423-8

PMCID:: PMC7515798

Abstract Article PDF–4.5M

Select item 67579965.

Regulation of APP-Dependent Transcription Complexes by Mint/X11s: Differential Functions of Mint Isoforms

Thomas Biederer, Xinwei Cao, Thomas C. Südhof, Xinran Liu

J Neurosci. 2002 Sep 1; 22(17): 7340–7351. doi: 10.1523/JNEUROSCI.22-17-07340.2002

PMCID:: PMC6757996

Abstract Article PDF–1.0M

Select item 58667906.

Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes

Gustavo Martínez-Noël, Katja Luck, Simone Kühnle, Alice Desbuleux, Patricia Szajner, Jeffrey T. Galligan, Diana Rodriguez, Leon Zheng, Kathleen Boyland, Flavian Leclere, Quan Zhong, David E. Hill, Marc Vidal, Peter M. Howley

J Mol Biol. Author manuscript; available in PMC 2019 Mar 30.

Published in final edited form as: J Mol Biol. 2018 Mar 30; 430(7): 1024–1050. Published online 2018 Feb 6. doi: 10.1016/j.jmb.2018.01.021

PMCID:: PMC5866790

Abstract Article PDF–4.1M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 48058558.

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

Javier Rodriguez, Ruth Pilkington, Amaya Garcia Munoz, Lan K. Nguyen, Nora Rauch, Susan Kennedy, Naser Monsefi, Ana Herrero, Cormac T. Taylor, Alex von Kriegsheim

Cell Rep. 2016 Mar 22; 14(11): 2745–2760. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.043

PMCID:: PMC4805855

Abstract Article PDF–4.6M

Select item 47800319.

NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells

Hiroki J. Nakaoka, Toshiro Hara, Seiko Yoshino, Akane Kanamori, Yusuke Matsui, Teppei Shimamura, Hiroshi Sato, Yoshinori Murakami, Motoharu Seiki, Takeharu Sakamoto

Sci Rep. 2016; 6: 22784. Published online 2016 Mar 7. doi: 10.1038/srep22784

PMCID:: PMC4780031

Abstract Article PDF–2.3M

Select item 476457310.

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning

Koray Kırlı, Samir Karaca, Heinz Jürgen Dehne, Matthias Samwer, Kuan Ting Pan, Christof Lenz, Henning Urlaub, Dirk Görlich

eLife. 2015; 4: e11466. Published online 2015 Dec 17. doi: 10.7554/eLife.11466

PMCID:: PMC4764573

Abstract Article PDF–5.7M

Select item 461721111.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 414089412.

Mint Proteins Are Required for Synaptic Activity-dependent Amyloid Precursor Protein (APP) Trafficking and Amyloid β Generation

Sarah E. Sullivan, Gregory M. Dillon, Josefa M. Sullivan, Angela Ho

J Biol Chem. 2014 May 30; 289(22): 15374–15383. Published online 2014 Apr 17. doi: 10.1074/jbc.M113.541003

PMCID:: PMC4140894

Abstract Article PDF–2.3M

Select item 411027213.

FIH-1-Mint3 Axis Does Not Control HIF-1α Transcriptional Activity in Nucleus Pulposus Cells

Yuichiro Hirose, Zariel I. Johnson, Zachary R. Schoepflin, Dessislava Z. Markova, Kazuhiro Chiba, Yoshiaki Toyama, Irving M. Shapiro, Makarand V. Risbud

J Biol Chem. 2014 Jul 25; 289(30): 20594–20605. Published online 2014 May 27. doi: 10.1074/jbc.M114.565101