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Select item 109316341.

The CD177 c.1291A Allele Leads to a Loss of Membrane Expression and Mimics a CD177-Null Phenotype

Annalena Traum, Stefanie Jehle, Yannick Waxmann, Anne-Sophie Litmeyer, Heike Berghöfer, Gregor Bein, Reinhard Dammann, Alexander Perniss, Monika Burg-Roderfeld, Ulrich J. Sachs, Behnaz Bayat

Int J Mol Sci. 2024 Mar; 25(5): 2877. Published online 2024 Mar 1. doi: 10.3390/ijms25052877

PMCID:: PMC10931634

Abstract Article PDF–5.3M

Select item 88576472.

Competitively disrupting the neutrophil-specific receptor–autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation

Stephen F. Marino, Uwe Jerke, Susanne Rolle, Oliver Daumke, Ralph Kettritz

J Biol Chem. 2022 Mar; 298(3): 101598. Published online 2022 Jan 19. doi: 10.1016/j.jbc.2022.101598

PMCID:: PMC8857647

Abstract Article PDF–2.3M

Select item 86542393.

The neutrophil protein CD177 is a novel PDPN receptor that regulates human cancer-associated fibroblast physiology

Jillian L. Astarita, Shilpa Keerthivasan, Bushra Husain, Yasin Şenbabaoğlu, Erik Verschueren, Sarah Gierke, Victoria C. Pham, Sean M. Peterson, Cecile Chalouni, Andrew A. Pierce, Jennie R. Lill, Lino C. Gonzalez, Nadia Martinez-Martin, Shannon J. Turley

PLoS One. 2021; 16(12): e0260800. Published online 2021 Dec 8. doi: 10.1371/journal.pone.0260800

PMCID:: PMC8654239

Abstract Article PDF–2.1M

Select item 84867744.

CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells

Myung-Chul Kim, Nicholas Borcherding, Kawther K. Ahmed, Andrew P. Voigt, Ajaykumar Vishwakarma, Ryan Kolb, Paige N. Kluz, Gaurav Pandey, Umasankar De, Theodore Drashansky, Eric Y. Helm, Xin Zhang, Katherine N. Gibson-Corley, Julia Klesney-Tait, Yuwen Zhu, Jinglu Lu, Jinsong Lu, Xian Huang, Hongrui Xiang, Jinke Cheng, Dongyang Wang, Zheng Wang, Jian Tang, Jiajia Hu, Zhengting Wang, Hua Liu, Mingjia Li, Haoyang Zhuang, Dorina Avram, Daohong Zhou, Rhonda Bacher, Song Guo Zheng, Xuefeng Wu, Yousef Zakharia, Weizhou Zhang

Nat Commun. 2021; 12: 5764. Published online 2021 Oct 1. doi: 10.1038/s41467-021-26091-4

PMCID:: PMC8486774

Abstract Article PDF–3.6M

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 71279506.

Cancer cell-intrinsic function of CD177 in attenuating β-Catenin signaling

Paige N. Kluz, Ryan Kolb, Qing Xie, Nicholas Borcherding, Qi Liu, Yuewan Luo, Myung-Chul Kim, Linna Wang, Yinan Zhang, Wei Li, Christopher Stipp, Katherine N. Gibson-Corley, Chen Zhao, Hank Heng Qi, Andrew Bellizzi, Andy W. Tao, Sonia Sugg, Ronald J. Weigel, Daohong Zhou, Xian Shen, Weizhou Zhang

Oncogene. Author manuscript; available in PMC 2020 Aug 10.

Published in final edited form as: Oncogene. 2020 Apr; 39(14): 2877–2889. Published online 2020 Feb 10. doi: 10.1038/s41388-020-1203-x

PMCID:: PMC7127950

Abstract Article PDF–2.2M

Select item 64463527.

Increase expression of CD177 in Kawasaki disease

Ying-Hsien Huang, Mao-Hung Lo, Xin-Yuan Cai, Shih-Feng Liu, Ho-Chang Kuo

Pediatr Rheumatol Online J. 2019; 17: 13. Published online 2019 Apr 3. doi: 10.1186/s12969-019-0315-8

PMCID:: PMC6446352

Abstract Article PDF–895K

Select item 63445268.

Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki disease

Tai-Ming Ko, Jeng-Sheng Chang, Shih-Ping Chen, Yi-Min Liu, Chia-Jung Chang, Fuu-Jen Tsai, Yi-Ching Lee, Chien-Hsiun Chen, Yuan-Tsong Chen, Jer-Yuarn Wu

Sci Rep. 2019; 9: 328. Published online 2019 Jan 23. doi: 10.1038/s41598-018-36520-y

PMCID:: PMC6344526

Abstract Article PDF–1.3M

Select item 63251489.

Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer

Lars Mortimer Schiffmann, Melanie Fritsch, Florian Gebauer, Saskia Diana Günther, Neil Richard Stair, Jens Michael Seeger, Fabinshy Thangarajah, Georg Dieplinger, Marc Bludau, Hakan Alakus, Heike Göbel, Alexander Quaas, Thomas Zander, Frank Hilberg, Christiane Josephine Bruns, Hamid Kashkar, Oliver Coutelle

Br J Cancer. 2019 Jan 8; 120(1): 69–78. Published online 2018 Oct 31. doi: 10.1038/s41416-018-0198-3

PMCID:: PMC6325148

Abstract Article PDF–2.5M

Select item 628329310.

Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies

Christina Schiza, Dimitrios Korbakis, Efstratia Panteleli, Keith Jarvi, Andrei P. Drabovich, Eleftherios P. Diamandis

Mol Cell Proteomics. 2018 Dec; 17(12): 2480–2495. Published online 2018 Aug 10. doi: 10.1074/mcp.RA118.000749

PMCID:: PMC6283293

Abstract Article PDF–1.9M

Select item 568060811.

CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation

Ming Bai, Ricardo Grieshaber-Bouyer, Junxia Wang, Angela B. Schmider, Zachary S. Wilson, Liling Zeng, Olha Halyabar, Matthew D. Godin, Hung N. Nguyen, Anaïs Levescot, Pierre Cunin, Craig T. Lefort, Roy J. Soberman, Peter A. Nigrovic

Blood. 2017 Nov 9; 130(19): 2092–2100. Prepublished online 2017 Aug 14. doi: 10.1182/blood-2017-03-768507

PMCID:: PMC5680608

Abstract Article

Select item 550242512.

Gene silencing and a novel monoallelic expression pattern in distinct CD177 neutrophil subsets

Claudia Eulenberg-Gustavus, Sylvia Bähring, Philipp G. Maass, Friedrich C. Luft, Ralph Kettritz

J Exp Med. 2017 Jul 3; 214(7): 2089–2101. doi: 10.1084/jem.20161093

PMCID:: PMC5502425

Abstract Article PDF–1.5M

Select item 532741213.

Characterization of the CD177 interaction with the ANCA antigen proteinase 3

Uwe Jerke, Stephen F. Marino, Oliver Daumke, Ralph Kettritz

Sci Rep. 2017; 7: 43328. Published online 2017 Feb 27. doi: 10.1038/srep43328

PMCID:: PMC5327412

Abstract Article PDF–1.6M

Select item 488205914.

Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion

Zuopeng Wu, Rong Liang, Thomas Ohnesorg, Vicky Cho, Wesley Lam, Walter P. Abhayaratna, Paul A. Gatenby, Chandima Perera, Yafei Zhang, Belinda Whittle, Andrew Sinclair, Christopher C. Goodnow, Matthew Field, T. Daniel Andrews, Matthew C. Cook

PLoS Genet. 2016 May; 12(5): e1006067. Published online 2016 May 26. doi: 10.1371/journal.pgen.1006067

PMCID:: PMC4882059

Abstract Article PDF–5.0M

Select item 444916315.

Genetic Mechanism of Human Neutrophil Antigen 2 Deficiency and Expression Variations

Yunfang Li, David C. Mair, Randy M. Schuller, Ling Li, Jianming Wu

PLoS Genet. 2015 May; 11(5): e1005255. Published online 2015 May 29. doi: 10.1371/journal.pgen.1005255

Correction in:: PLoS Genet. 2015 Jun; 11(6): e1005360.

PMCID:: PMC4449163

Abstract Article PDF–1.1M

Select item 426658816.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 415453617.

Neutrophil Transmigration Mediated by the Neutrophil-Specific Antigen CD177 Is Influenced by the Endothelial S₅₃₆N Dimorphism of Platelet Endothelial Cell Adhesion Molecule-1

Behnaz Bayat, Silke Werth, Ulrich J. H. Sachs, Debra K. Newman, Peter J. Newman, Sentot Santoso

J Immunol. Author manuscript; available in PMC 2014 Sep 4.

Published in final edited form as: J Immunol. 2010 Apr 1; 184(7): 3889–3896. Published online 2010 Mar 1. doi: 10.4049/jimmunol.0903136

PMCID:: PMC4154536

Abstract Article PDF–405K

Select item 405722218.

Differential Expression of Granulopoiesis Related Genes in Neutrophil Subsets Distinguished by Membrane Expression of CD177

Nan Hu, Helena Mora-Jensen, Kim Theilgaard-Mönch, Berber Doornbos-van der Meer, Minke G. Huitema, Coen A. Stegeman, Peter Heeringa, Cees G. M. Kallenberg, Johanna Westra

PLoS One. 2014; 9(6): e99671. Published online 2014 Jun 13. doi: 10.1371/journal.pone.0099671

PMCID:: PMC4057222

Abstract Article PDF–1.9M

Select item 394814119.

Relevance of novel inflammatory markers in stroke-induced immunosuppression

András Folyovich, Enikő Biró, Csaba Orbán, Anna Bajnok, Viktória Varga, Anna K Béres-Molnár, Barna Vásárhelyi, Gergely Toldi

BMC Neurol. 2014; 14: 41. Published online 2014 Mar 6. doi: 10.1186/1471-2377-14-41

PMCID:: PMC3948141

Abstract Article PDF–586K

Select item 377350520.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

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