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Select item 111278071.

Role of Ubiquitin-conjugating enzyme E2 (UBE2) in two immune-mediated inflammatory skin diseases: a mendelian randomization analysis

Xiaoxue Wang, Zexin Zhu

Arch Dermatol Res. 2024; 316(6): 249. Published online 2024 May 25. doi: 10.1007/s00403-024-02976-4

PMCID:: PMC11127807

Abstract Article PDF–1.9M

Select item 110431092.

UBE2L3 expression in human gastric cancer and its clinical significance

Xiaoxia Zhang, Yujie Wei, Fanqi Wu, Mei Li, Cong Han, Chengdong Huo, Zhi Li, Futian Tang, Wenting He, Yang Zhao, Yumin Li

J Cancer Res Clin Oncol. 2024; 150(4): 210. Published online 2024 Apr 24. doi: 10.1007/s00432-024-05669-7

PMCID:: PMC11043109

Abstract Article PDF–6.0M

Select item 108978943.

The E3 ligase SMURF1 stabilizes p27 via UbcH7 catalyzed K29-linked ubiquitin chains to promote cell migration SMURF1-UbcH7 K29 ubiquitination of p27 and cell migration

Jasper Weinberg, Elizabeth Whitcomb, Andrew Bohm, Uday Kumar Chekkilla, Allen Taylor

J Biol Chem. 2024 Mar; 300(3): 105693. Published online 2024 Feb 1. doi: 10.1016/j.jbc.2024.105693

PMCID:: PMC10897894

Abstract Article PDF–3.0M

Select item 108781004.

The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer

Mohamed I. Khalil, Canchai Yang, Lexi Vu, Smriti Chadha, Harrison Nabors, Claire D. James, Iain M. Morgan, Dohun Pyeon

J Virol. 2024 Feb; 98(2): e01726-23. Published online 2024 Jan 16. doi: 10.1128/jvi.01726-23

PMCID:: PMC10878100

Abstract Article PDF–3.0M

Select item 108698005.

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett

Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4

PMCID:: PMC10869800

Abstract Article PDF–9.3M

Select item 105093116.

KIAA0317 regulates SOCS1 stability to ameliorate colonic inflammation

Karina C. Lockwood, Travis B. Lear, Shristi Rajbhandari, Alison C. McKelvey, Sarah R. Dunn, Áine N. Boudreau, Yuan Liu, Bill B. Chen

FEBS J. Author manuscript; available in PMC 2023 Sep 28.

Published in final edited form as: FEBS J. 2023 Aug; 290(15): 3802–3811. Published online 2023 Apr 7. doi: 10.1111/febs.16780

PMCID:: PMC10509311

Abstract Article PDF–1.6M

Select item 102374227.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101561758.

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman

Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035

Correction in:: Cell. 2023 May 25; 186(11): 2492.

PMCID:: PMC10156175

Abstract Article

Select item 99544139.

E2 Partner Tunes the Ubiquitylation Specificity of Arkadia E3 Ubiquitin Ligase

Georgia N. Delegkou, Maria Birkou, Nefeli Fragkaki, Tamara Toro, Konstantinos D. Marousis, Vasso Episkopou, Georgios A. Spyroulias

Cancers (Basel) 2023 Feb; 15(4): 1040. Published online 2023 Feb 7. doi: 10.3390/cancers15041040

PMCID:: PMC9954413

Abstract Article PDF–20M

Select item 994364810.

A bio-orthogonal linear ubiquitin probe identifies STAT3 as a direct substrate of OTULIN in glioblastoma

Xianli Du, Jing Pang, Bin Gu, Tian Si, Yan Chang, Tianqi Li, Min Wu, Zicheng Wang, Yuxia Wang, Jiannan Feng, Ning Wu, Jianghong Man, Huiyan Li, Ailing Li, Tong Zhang, Bo Wang, Xiaotao Duan

Nucleic Acids Res. 2023 Feb 22; 51(3): 1050–1066. Published online 2023 Jan 20. doi: 10.1093/nar/gkad002

PMCID:: PMC9943648

Abstract Article PDF–5.3M

Select item 992963111.

Recognition of the CCT5 di‐Glu degron by CRL4^DCAF12 is dependent on TRiC assembly

Carlos Pla‐Prats, Simone Cavadini, Georg Kempf, Nicolas H Thomä

EMBO J. 2023 Feb; 42(4): e112253. Published online 2023 Jan 30. doi: 10.15252/embj.2022112253

PMCID:: PMC9929631

Abstract Article PDF–4.3M

Select item 988326112.

Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor

Seung Un Seo, Seon Min Woo, Min Wook Kim, Eun-Woo Lee, Kyoung-jin Min, Taeg Kyu Kwon

Cell Death Differ. 2023 Jan; 30(1): 82–93. Published online 2022 Aug 4. doi: 10.1038/s41418-022-01047-3

PMCID:: PMC9883261

Abstract Article PDF–4.6M

Select item 986049613.

Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method

Ryota Hayashida, Reika Kikuchi, Kenichiro Imai, Waka Kojima, Tatsuya Yamada, Miho Iijima, Hiromi Sesaki, Keiji Tanaka, Noriyuki Matsuda, Koji Yamano

J Biol Chem. 2023 Feb; 299(2): 102822. Published online 2022 Dec 21. doi: 10.1016/j.jbc.2022.102822

PMCID:: PMC9860496

Abstract Article PDF–6.6M

Select item 985317714.

Structural basis for ubiquitylation by HOIL-1

Qilong Wu, Marios G. Koliopoulos, Katrin Rittinger, Benjamin Stieglitz

Front Mol Biosci. 2022; 9: 1098144. Published online 2023 Jan 6. doi: 10.3389/fmolb.2022.1098144

PMCID:: PMC9853177

Abstract Article PDF–2.0M

Select item 985222415.

Mechanisms of MCL-1 protein stability induced by MCL-1 antagonists in B-cell malignancies

Shady I. Tantawy, Aloke Sarkar, Stefan Hubner, Zhi Tan, William G. Wierda, Abdelraouf Eldeib, Shuxing Zhang, Steven Kornblau, Varsha Gandhi

Clin Cancer Res. Author manuscript; available in PMC 2023 Jul 17.

Published in final edited form as: Clin Cancer Res. 2023 Jan 17; 29(2): 446–457. doi: 10.1158/1078-0432.CCR-22-2088

PMCID:: PMC9852224

Abstract Article PDF–2.1M

Select item 983425216.

The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family

Xiangyi S. Wang, Thomas R. Cotton, Sarah J. Trevelyan, Lachlan W. Richardson, Wei Ting Lee, John Silke, Bernhard C. Lechtenberg

Nat Commun. 2023; 14: 168. Published online 2023 Jan 11. doi: 10.1038/s41467-023-35871-z

PMCID:: PMC9834252

Abstract Article PDF–4.2M

Select item 975347117.

LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF‐κB to the nucleus

Zhixiao Wu, Lena A Berlemann, Verian Bader, Dominik A Sehr, Eva Dawin, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas B Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F Winklhofer

EMBO J. 2022 Dec; 41(24): e112006. Published online 2022 Nov 18. doi: 10.15252/embj.2022112006

PMCID:: PMC9753471

Abstract Article PDF–4.3M

Select item 963697118.

HOIP modulates the stability of GPx4 by linear ubiquitination

Kangyun Dong, Ran Wei, Taijie Jin, Mengmeng Zhang, Jiali Shen, Huaijiang Xiang, Bing Shan, Junying Yuan, Ying Li

Proc Natl Acad Sci U S A. 2022 Nov 1; 119(44): e2214227119. Published online 2022 Oct 24. doi: 10.1073/pnas.2214227119

PMCID:: PMC9636971

Abstract Article PDF–2.3M

Select item 948193319.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 948160220.

Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function

Simon Maria Kienle, Tobias Schneider, Katrin Stuber, Christoph Globisch, Jasmin Jansen, Florian Stengel, Christine Peter, Andreas Marx, Michael Kovermann, Martin Scheffner

Nat Commun. 2022; 13: 5435. Published online 2022 Sep 16. doi: 10.1038/s41467-022-33087-1

PMCID:: PMC9481602

Abstract Article PDF–3.7M

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PMC Links for GEO Profiles (Select 65020026) (241)
PMC
transcription factor E2F8 isoform X1 [Homo sapiens]
transcription factor E2F8 isoform X1 [Homo sapiens]
gi|767966548|ref|XP_011518669.1|

Protein
E2F8 protein, partial [Homo sapiens]
E2F8 protein, partial [Homo sapiens]
gi|83318448|gb|AAI08701.1|

Protein
Homo sapiens cDNA FLJ46067 fis, clone TESOP2002110
Homo sapiens cDNA FLJ46067 fis, clone TESOP2002110
gi|34535092|dbj|AK127956.1|

Nucleotide
Homo sapiens mRNA for IKIP1 (IKIP gene)
Homo sapiens mRNA for IKIP1 (IKIP gene)
gi|41529133|emb|AJ539425.1|

Nucleotide

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