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Select item 111136071.

Nanobody-induced perturbation of LFA-1/L-plastin phosphorylation impairs MTOC docking, immune synapse formation and T cell activation

Sarah De Clercq, Olivier Zwaenepoel, Evelien Martens, Joël Vandekerckhove, Aude Guillabert, Jan Gettemans

Cell Mol Life Sci. 2013 Mar; 70(5): 909–922. Published online 2012 Sep 23. doi: 10.1007/s00018-012-1169-0

PMCID:: PMC11113607

Abstract Article PDF–860K

Select item 110229872.

Soluble uric acid inhibits β₂ integrin–mediated neutrophil recruitment in innate immunity

Qiuyue Ma, Roland Immler, Monika Pruenster, Markus Sellmayr, Chenyu Li, Albrecht von Brunn, Brigitte von Brunn, Rosina Ehmann, Roman Wölfel, Matteo Napoli, Qiubo Li, Paola Romagnani, Ralph Thomas Böttcher, Markus Sperandio, Hans-Joachim Anders, Stefanie Steiger

Blood. 2022 Jun 9; 139(23): 3402–3417. Published online 2022 Mar 22. doi: 10.1182/blood.2021011234

PMCID:: PMC11022987

Abstract Article

Select item 109929273.

ITGB2 as a prognostic indicator and a predictive marker for immunotherapy in gliomas

Houshi Xu, Anke Zhang, Xiaying Han, Yanning Li, Zeyu Zhang, Liying Song, Wei Wang, Meiqing Lou

Cancer Immunol Immunother. 2022 Mar; 71(3): 645–660. Published online 2021 Jul 27. doi: 10.1007/s00262-021-03022-2

PMCID:: PMC10992927

Abstract Article PDF–8.3M

Select item 106043254.

Aminopeptidase N/CD13 Crosslinking Promotes the Activation and Membrane Expression of Integrin CD11b/CD18

Laura Díaz-Alvarez, Mariana Esther Martínez-Sánchez, Eleanor Gray, Erandi Pérez-Figueroa, Enrique Ortega

Biomolecules. 2023 Oct; 13(10): 1488. Published online 2023 Oct 6. doi: 10.3390/biom13101488

PMCID:: PMC10604325

Abstract Article PDF–3.5M

Select item 104636745.

Association of integrin-β2 polymorphism and expression with the risk of rheumatoid arthritis and osteoarthritis in Egyptian patients

Aliaa M. Selim, Yumn A. Elsabagh, Maha M. El-Sawalhi, Nabila A. Ismail, Mahmoud A. Senousy

BMC Med Genomics. 2023; 16: 204. Published online 2023 Aug 29. doi: 10.1186/s12920-023-01635-3

PMCID:: PMC10463674

Abstract Article PDF–2.0M

Select item 102960286.

Targeting Neutrophil β₂-Integrins: A Review of Relevant Resources, Tools, and Methods

Haleigh E. Conley, M. Katie Sheats

Biomolecules. 2023 Jun; 13(6): 892. Published online 2023 May 26. doi: 10.3390/biom13060892

PMCID:: PMC10296028

Abstract Article PDF–445K

Select item 102794697.

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein

Sean A. Burnap, Ana Maria Ortega-Prieto, Jose M. Jimenez-Guardeño, Hashim Ali, Kaloyan Takov, Matthew Fish, Manu Shankar-Hari, Mauro Giacca, Michael H. Malim, Manuel Mayr

Mol Cell Proteomics. 2023 Aug; 22(8): 100600. Published online 2023 Jun 19. doi: 10.1016/j.mcpro.2023.100600

PMCID:: PMC10279469

Abstract Article PDF–3.2M

Select item 102251238.

Identifying C1QB, ITGAM, and ITGB2 as potential diagnostic candidate genes for diabetic nephropathy using bioinformatics analysis

Yongzheng Hu, Yani Yu, Hui Dong, Wei Jiang

PeerJ. 2023; 11: e15437. Published online 2023 May 25. doi: 10.7717/peerj.15437

PMCID:: PMC10225123

Abstract Article PDF–4.2M

Select item 98801579.

Correlation between ITGB2 expression and clinical characterization of glioma and the prognostic significance of its methylation in low-grade glioma(LGG)

He Liu, Jiao Wang, Tao Luo, Zhiming Zhen, Li Liu, Yalan Zheng, Chaobin Zhang, Xiaofei Hu

Front Endocrinol (Lausanne) 2022; 13: 1106120. Published online 2023 Jan 13. doi: 10.3389/fendo.2022.1106120

PMCID:: PMC9880157

Abstract Article PDF–3.5M

Select item 850863210.

Integrin β1 Promotes Pancreatic Tumor Growth by Upregulating Kindlin-2 and TGF-β Receptor-2

Md Saimon Mia, Yagna Jarajapu, Reena Rao, Sijo Mathew

Int J Mol Sci. 2021 Oct; 22(19): 10599. Published online 2021 Sep 30. doi: 10.3390/ijms221910599

PMCID:: PMC8508632

Abstract Article PDF–1.9M

Select item 825527611.

Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in preeclampsia: a genetic and functional study

Lokki AI, L Teirilä, M Triebwasser, E Daly, A Bhattacharjee, L Uotila, M Llort Asens, MI Kurki, M Perola, K Auro, JE Salmon, M Daly, JP Atkinson, H Laivuori, S Fagerholm, S Meri, FINNPEC

BJOG. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: BJOG. 2021 Jul; 128(8): 1282–1291. Published online 2021 Mar 14. doi: 10.1111/1471-0528.16660

PMCID:: PMC8255276

Abstract Article PDF–1.3M

Select item 821421812.

Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin

Carlos Angel Espinosa-Vinals, Jiri Masin, Jana Holubova, Ondrej Stanek, David Jurnecka, Radim Osicka, Peter Sebo, Ladislav Bumba

J Biol Chem. 2021 Jul; 297(1): 100833. Published online 2021 May 26. doi: 10.1016/j.jbc.2021.100833

PMCID:: PMC8214218

Abstract Article PDF–1.8M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 810117514.

Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses

Kotaro Matsumoto, Takahiko Kurasawa, Keiko Yoshimoto, Katsuya Suzuki, Tsutomu Takeuchi

Arthritis Res Ther. 2021; 23: 136. Published online 2021 May 6. doi: 10.1186/s13075-021-02510-1

PMCID:: PMC8101175

Abstract Article PDF–1.5M

Select item 794879815.

Complement receptor 3 mediates both sinking phagocytosis and phagocytic cup formation via distinct mechanisms

Stefan Walbaum, Benjamin Ambrosy, Paula Schütz, Anne C. Bachg, Markus Horsthemke, Jeanette H.W. Leusen, Attila Mócsai, Peter J. Hanley

J Biol Chem. 2021 Jan-Jun; 296: 100256. Published online 2021 Jan 8. doi: 10.1016/j.jbc.2021.100256

PMCID:: PMC7948798

Abstract Article PDF–10M

Select item 779619416.

Structural assessment of SARS-CoV2 accessory protein ORF7a predicts LFA-1 and Mac-1 binding potential

Zubair Ahmed Nizamudeen, Emma-Ruoqi Xu, Vivin Karthik, Mohamed Halawa, Kenton P. Arkill, Andrew M. Jackson, David O. Bates, Jonas Emsley

Biosci Rep. 2021 Jan 29; 41(1): BSR20203837. Published online 2021 Jan 8. doi: 10.1042/BSR20203837

PMCID:: PMC7796194

Abstract Article PDF–1.2M

Select item 777251017.

Moieties of Complement iC3b Recognized by the I-domain of Integrin αXβ2

Jeongsuk Choi, Dolgorsuren Buyannemekh, Sang-Uk Nham

Mol Cells. 2020 Dec 31; 43(12): 1023–1034. Published online 2020 Dec 29. doi: 10.14348/molcells.2020.0197

PMCID:: PMC7772510

Abstract Article PDF–2.3M

Select item 766769318.

ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system

Xiaoxin Zhang, Yingchun Dong, Mengxiang Zhao, Liang Ding, Xihu Yang, Yue Jing, Yuxian Song, Sheng Chen, Qingang Hu, Yanhong Ni

Theranostics. 2020; 10(26): 12044–12059. Published online 2020 Oct 26. doi: 10.7150/thno.47901

PMCID:: PMC7667693

Abstract Article PDF–3.7M

Select item 751822719.

CD64, CD11a and CD18 leukocytes expression in children with SARS-CoV-2 multisystem inflammatory syndrome versus children with Kawasaki disease: Similar but not the same

Alberto García-Salido, Sandra Cuenca-Carcelén, Ana Castillo-Robleda

Med Clin (Barc) 2021 Jan 22; 156(2): 89–91. Published online 2020 Sep 25. doi: 10.1016/j.medcli.2020.09.002

PMCID:: PMC7518227

Article PDF–504K

Select item 740685720.

β₂-integrin LFA1 mediates airway damage following neutrophil transepithelial migration during respiratory syncytial virus infection

Jenny Amanda Herbert, Yu Deng, Pia Hardelid, Elisabeth Robinson, Luo Ren, Dale Moulding, Rosalind Louise Smyth, Claire Mary Smith

Eur Respir J. 2020 Aug; 56(2): 1902216. Published online 2020 Aug 6. doi: 10.1183/13993003.02216-2019

PMCID:: PMC7406857

Abstract Article PDF–1.2M

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