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Items: 1 to 20 of 81

1.
Upregulated Expression of IL2RB Causes Disorder of Immune Microenvironment in Patients with Kawasaki Disease
Yunfei Liao, Ben Ke, Xiaoyan Long, Jianjun Xu, Yongbing Wu
Biomed Res Int. 2022; 2022: 2114699. Published online 2022 Jul 25. doi: 10.1155/2022/2114699
PMCID:
PMC9343205
AbstractArticlePDF–1.9M
2.
Soluble IL-2R Levels at Baseline Predict the Development of Severe Respiratory Failure and Mortality in COVID-19 Patients
Nikolaos K. Gatselis, Vasiliki Lygoura, Aggeliki Lyberopoulou, George Giannoulis, Anna Samakidou, Antonia Vaiou, George Vatidis, Katerina Antoniou, Aggelos Stefos, Sarah Georgiadou, Dimitrios Sagris, Dafni Sveroni, Despoina Stergioula, Stella Gabeta, George Ntaios, George N. Dalekos
Viruses. 2022 Apr; 14(4): 787. Published online 2022 Apr 10. doi: 10.3390/v14040787
PMCID:
PMC9025750
AbstractArticlePDF–589K
3.
Liver Injury and Elevated Levels of Interleukins, Interleukin-2 Receptor, and Interleukin-6 Predict the Severity in Patients With COVID-19
Kuan Luo, Yongfeng Chen, Junjie Yang, Quan Tao, Min Luo
Front Public Health. 2021; 9: 778340. Published online 2021 Dec 14. doi: 10.3389/fpubh.2021.778340
PMCID:
PMC8713698
AbstractArticlePDF–367K
4.
Downregulation of miR-497-5p Improves Sepsis-Induced Acute Lung Injury by Targeting IL2RB
Wei Lou, Jieping Yan, Weisi Wang
Biomed Res Int. 2021; 2021: 6624702. Published online 2021 Apr 12. doi: 10.1155/2021/6624702
PMCID:
PMC8057895
AbstractArticlePDF–2.4M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
IL‐2 gene C/T polymorphism is associated with prostate cancer
Hsi‐Chin Wu, Chao‐Hsiang Chang, Lei Wan, Chao‐I Wu, Fuu‐Jen Tsai, Wen‐Chi Chen
J Clin Lab Anal. 2006; 20(6): 245–249. Published online 2006 Nov 17. doi: 10.1002/jcla.20149
PMCID:
PMC6807315
AbstractArticlePDF–121K
7.
Single nucleotide polymorphisms of the genes IL-2, IL-2RB, and JAK3 in patients with cutaneous leishmaniasis caused by Leishmania (V.) guyanensis in Manaus, Amazonas, Brazil
Felipe Jules de Araújo Santos, Lener Santos da Silva, José do Espírito Santo Júnior, Tirza Gabrielle Ramos de Mesquita, Mara Lúcia Gomes de Souza, Moacir Couto de Andrade Júnior, Sinésio Talhari, Rajendranath Ramasawmy
PLoS One. 2019; 14(8): e0220572. Published online 2019 Aug 8. doi: 10.1371/journal.pone.0220572
PMCID:
PMC6687158
AbstractArticlePDF–528K
8.
Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance
Zinan Zhang, Florian Gothe, Perrine Pennamen, John R. James, David McDonald, Carlos P. Mata, Yorgo Modis, Anas M. Alazami, Meghan Acres, Wolfram Haller, Claire Bowen, Rainer Döffinger, Jan Sinclair, Shannon Brothers, Yu Zhang, Helen F. Matthews, Sophie Naudion, Fanny Pelluard, Huda Alajlan, Yasuhiro Yamazaki, Luigi D. Notarangelo, James E. Thaventhiran, Karin R. Engelhardt, Hamoud Al-Mousa, Sophie Hambleton, Caroline Rooryck, Kenneth G.C. Smith, Michael J. Lenardo
J Exp Med. 2019 Jun 3; 216(6): 1311–1327. Published online 2019 Apr 30. doi: 10.1084/jem.20182304
PMCID:
PMC6547869
AbstractArticlePDF–3.6M
9.
A novel human IL2RB mutation results in T and NK cell–driven immune dysregulation
Isabel Z. Fernandez, Ryan M. Baxter, Josselyn E. Garcia-Perez, Elena Vendrame, Thanmayi Ranganath, Daniel S. Kong, Karl Lundquist, Tom Nguyen, Sidney Ogolla, Jennifer Black, Csaba Galambos, James C. Gumbart, Noor Dawany, Judith R. Kelsen, Edwin F. de Zoeten, Ralph Quinones, Hesham Eissa, Michael R. Verneris, Kathleen E. Sullivan, Rosemary Rochford, Catherine A. Blish, Ross M. Kedl, Cullen M. Dutmer, Elena W.Y. Hsieh
J Exp Med. 2019 Jun 3; 216(6): 1255–1267. Published online 2019 Apr 30. doi: 10.1084/jem.20182015
Correction in:
J Exp Med. 2019 Jun 3; 216(6): 1465.
PMCID:
PMC6547857
AbstractArticlePDF–2.9M
10.
ZNF300, a recently identified human transcription factor, activates the human IL-2Rβ promoter through the overlapping ZNF300/EGR1 binding site
Lu Xue, Hongling Qiu, Jian Ma, Mingxiong Guo, Wenxin Li
Cell Mol Biol Lett. 2010 Dec; 15(4): 530–540. Published online 2010 Jun 28. doi: 10.2478/s11658-010-0025-1
PMCID:
PMC6275642
SummaryPDF–1.2M
11.
Tethering IL2 to its receptor IL2Rβ enhances anti-tumor activity and expansion of natural killer NK92 cells
Youssef Jounaidi, Joseph F. Cotten, Keith W. Miller, Stuart A. Forman
Cancer Res. Author manuscript; available in PMC 2018 Oct 28.
Published in final edited form as: Cancer Res. 2017 Nov 1; 77(21): 5938–5951. Published online 2017 Sep 15. doi: 10.1158/0008-5472.CAN-17-1007
PMCID:
PMC6204197
AbstractArticlePDF–2.3M
12.
CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia
Qing-Yun Wu, Yuan-Yuan Zhu, Yang Liu, Fang Wei, Yu-Xue Tong, Jiang Cao, Ping Zhou, Ming-Shan Niu, Zhen-Yu Li, Ling-Yu Zeng, Feng Li, Kai-Lin Xu
Cell Death Dis. 2018 Jul; 9(7): 774. Published online 2018 Jul 10. doi: 10.1038/s41419-018-0812-6
PMCID:
PMC6039501
AbstractArticlePDF–2.7M
13.
The molecular basis of JAK/STAT inhibition by SOCS1
Nicholas P. D. Liau, Artem Laktyushin, Isabelle S. Lucet, James M. Murphy, Shenggen Yao, Eden Whitlock, Kimberley Callaghan, Nicos A. Nicola, Nadia J. Kershaw, Jeffrey J. Babon
Nat Commun. 2018; 9: 1558. Published online 2018 Apr 19. doi: 10.1038/s41467-018-04013-1
PMCID:
PMC5908791
AbstractArticlePDF–2.7M
14.
A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects
Yuki Kagoya, Shinya Tanaka, Tingxi Guo, Mark Anczurowski, Chung-Hsi Wang, Kayoko Saso, Marcus O. Butler, Mark D. Minden, Naoto Hirano
Nat Med. Author manuscript; available in PMC 2018 Aug 5.
Published in final edited form as: Nat Med. 2018 Mar; 24(3): 352–359. Published online 2018 Feb 5. doi: 10.1038/nm.4478
PMCID:
PMC5839992
AbstractArticlePDF–2.0M
15.
Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants
Digna R. Velez, Stephen Fortunato, Poul Thorsen, Salvatore J. Lombardi, Scott M. Williams, Ramkumar Menon
Am J Obstet Gynecol. Author manuscript; available in PMC 2016 Apr 12.
Published in final edited form as: Am J Obstet Gynecol. 2009 Feb; 200(2): 209.e1–209.27. Published online 2008 Nov 18. doi: 10.1016/j.ajog.2008.08.051
PMCID:
PMC4829203
AbstractArticlePDF–164K
16.
Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage
Romain Drissi, Marie-Line Dubois, Mélanie Douziech, François-Michel Boisvert
Mol Cell Proteomics. 2015 Jul; 14(7): 2002–2013. Published online 2015 May 11. doi: 10.1074/mcp.M115.048991
PMCID:
PMC4587322
AbstractArticlePDF–3.0M
17.
Interleukin-2 Receptor β Thr-450 Phosphorylation Is a Positive Regulator for Receptor Complex Stability and Activation of Signaling Molecules
Blanca E. Ruiz-Medina, Jeremy A. Ross, Robert A. Kirken
J Biol Chem. 2015 Aug 21; 290(34): 20972–20983. Published online 2015 Jul 7. doi: 10.1074/jbc.M115.660654
PMCID:
PMC4543656
AbstractArticlePDF–1.7M
18.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
19.
A Large-Scale, Consortium-Based Genomewide Association Study of Asthma
Miriam F. Moffatt, Ivo G. Gut, Florence Demenais, David P. Strachan, Emmanuelle Bouzigon, Simon Heath, Erika von Mutius, Martin Farrall, Mark Lathrop, William O.C.M. Cookson
N Engl J Med. Author manuscript; available in PMC 2014 Dec 9.
Published in final edited form as: N Engl J Med. 2010 Sep 23; 363(13): 1211–1221. doi: 10.1056/NEJMoa0906312
PMCID:
PMC4260321
AbstractArticlePDF–869K
20.
Modulation of CD112 by the alphaherpesvirus gD protein suppresses DNAM-1–dependent NK cell-mediated lysis of infected cells
Korneel Grauwet, Claudia Cantoni, Monica Parodi, Andrea De Maria, Bert Devriendt, Daniela Pende, Lorenzo Moretta, Massimo Vitale, Herman W. Favoreel
Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45): 16118–16123. Published online 2014 Oct 28. doi: 10.1073/pnas.1409485111
PMCID:
PMC4234607
AbstractArticlePDF–937K

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