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Select item 107994841.

CNS erythroblastic sarcoma: a potential emerging pediatric tumor type characterized by NFIA::RUNX1T1/3 fusions

Arnault Tauziède-Espariat, Lucille Lew-Derivry, Samuel Abbou, Alice Métais, Gaëlle Pierron, Stéphanie Reynaud, Julien Masliah-Planchon, Cassandra Mariet, Lauren Hasty, Volodia Dangouloff-Ros, Nathalie Boddaert, Marie Csanyi, Aude Aline-Fardin, Claire Lamaison, Fabrice Chrétien, Kévin Beccaria, Stéphanie Puget, Pascale Varlet

Acta Neuropathol Commun. 2024; 12: 12. Published online 2024 Jan 19. doi: 10.1186/s40478-023-01708-5

PMCID:: PMC10799484

Abstract Article PDF–1.5M

Select item 91052352.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80459324.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 75442365.

Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization

Xiang Guo, Jennifer Plank-Bazinet, Ivan Krivega, Ryan K Dale, Ann Dean

Nucleic Acids Res. 2020 Oct 9; 48(18): 10226–10240. Published online 2020 Sep 22. doi: 10.1093/nar/gkaa736

PMCID:: PMC7544236

Abstract Article PDF–4.9M

Select item 73357796.

The transcriptional corepressor CBFA2T3 inhibits all-trans-retinoic acid–induced myeloid gene expression and differentiation in acute myeloid leukemia

Nickolas Steinauer, Chun Guo, Jinsong Zhang

J Biol Chem. 2020 Jul 3; 295(27): 8887–8900. Published online 2020 May 20. doi: 10.1074/jbc.RA120.013042

PMCID:: PMC7335779

Abstract Article PDF–4.0M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67134758.

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance

Matthew F Pech, Linda E Fong, Jacqueline E Villalta, Leanne JG Chan, Samir Kharbanda, Jonathon J O'Brien, Fiona E McAllister, Ari J Firestone, Calvin H Jan, Jeffrey Settleman

eLife. 2019; 8: e47362. Published online 2019 Aug 27. doi: 10.7554/eLife.47362

PMCID:: PMC6713475

Abstract Article PDF–4.6M

Select item 67100449.

Genome-wide association study identifies CBFA2T3 affecting the rate of CSF Aβ₄₂ decline in non-demented elders

Kai-Xin Dou, Can Zhang, Chen-Chen Tan, Wei Xu, Jie-Qiong Li, Xi-Peng Cao, Lan Tan, Jin-Tai Yu, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

Aging (Albany NY) 2019 Aug 15; 11(15): 5433–5444. Published online 2019 Aug 1. doi: 10.18632/aging.102125

PMCID:: PMC6710044

Abstract Article PDF–1.8M

Select item 658652010.

Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma

Sarah P. Short, Caitlyn W. Barrett, Kristy R. Stengel, Frank L. Revetta, Yash A. Choksi, Lori A. Coburn, Mary K. Lintel, Elizabeth M. Mcdonough, M. Kay Washington, Keith T. Wilson, Egor Prokhortchouk, Xi Chen, Scott W. Hiebert, Albert B. Reynolds, Christopher S. Williams

Oncogene. Author manuscript; available in PMC 2019 Sep 11.

Published in final edited form as: Oncogene. 2019 Jun; 38(25): 5091–5106. Published online 2019 Mar 11. doi: 10.1038/s41388-019-0777-7

Correction in:: Oncogene. 2019 May 8

PMCID:: PMC6586520

Abstract Article PDF–2.8M

Select item 651766811.

Myeloid translocation gene CBFA2T3 directs a relapse gene program and determines patient-specific outcomes in AML

Nickolas Steinauer, Chun Guo, Chunfa Huang, Madeline Wong, Yifan Tu, Carl E. Freter, Jinsong Zhang

Blood Adv. 2019 May 14; 3(9): 1379–1393. Published online 2019 Apr 30. doi: 10.1182/bloodadvances.2018028514

PMCID:: PMC6517668

Abstract Article PDF–1.9M

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 546865013.

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation

Ferdinand M. Huber, Sarah M. Greenblatt, Andrew M. Davenport, Concepcion Martinez, Ye Xu, Ly P. Vu, Stephen D. Nimer, André Hoelz

Proc Natl Acad Sci U S A. 2017 Jun 6; 114(23): 6016–6021. Published online 2017 May 22. doi: 10.1073/pnas.1700328114

PMCID:: PMC5468650

Abstract Article PDF–1.3M

Select item 537173014.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 520418915.

Clinical Courses of Two Pediatric Patients with Acute Megakaryoblastic Leukemia Harboring the CBFA2T3-GLIS2 Fusion Gene

Mayu Ishibashi, Tomoko Yokosuka, Masakatsu D. Yanagimachi, Fuminori Iwasaki, Shin-ichi Tsujimoto, Koji Sasaki, Masanobu Takeuchi, Reo Tanoshima, Hiromi Kato, Ryosuke Kajiwara, Fumiko Tanaka, Hiroaki Goto, Shumpei Yokota

Turk J Haematol. 2016 Dec; 33(4): 331–334. Published online 2016 Dec 1. doi: 10.4274/tjh.2016.0008

PMCID:: PMC5204189

Abstract Article PDF–314K

Select item 514077016.

Myeloid translocation genes differentially regulate colorectal cancer programs

Bobak Parang, Amber M. Bradley, Mukul K. Mittal, Sarah P. Short, Joshua J. Thompson, Caitlyn W. Barrett, Rishi D. Naik, Anthony J. Bilotta, Mary K. Washington, Frank L. Revetta, Jesse J. Smith, Xi Chen, Keith T. Wilson, Scott W. Hiebert, Christopher S. Williams

Oncogene. Author manuscript; available in PMC 2016 Dec 9.

Published in final edited form as: Oncogene. 2016 Dec 8; 35(49): 6341–6349. Published online 2016 Jun 6. doi: 10.1038/onc.2016.167

PMCID:: PMC5140770

Abstract Article PDF–2.5M

Select item 467383417.

Control of developmentally primed erythroid genes by combinatorial co-repressor actions

Ralph Stadhouders, Alba Cico, Tharshana Stephen, Supat Thongjuea, Petros Kolovos, H. Irem Baymaz, Xiao Yu, Jeroen Demmers, Karel Bezstarosti, Alex Maas, Vilma Barroca, Christel Kockx, Zeliha Ozgur, Wilfred van Ijcken, Marie-Laure Arcangeli, Charlotte Andrieu-Soler, Boris Lenhard, Frank Grosveld, Eric Soler

Nat Commun. 2015; 6: 8893. Published online 2015 Nov 23. doi: 10.1038/ncomms9893

PMCID:: PMC4673834

Abstract Article PDF–2.7M

Select item 443171218.

Myeloid Translocation Gene-16 Co-Repressor Promotes Degradation of Hypoxia-Inducible Factor 1

Parveen Kumar, Urban Gullberg, Inge Olsson, Ram Ajore

PLoS One. 2015; 10(5): e0123725. Published online 2015 May 14. doi: 10.1371/journal.pone.0123725

PMCID:: PMC4431712

Abstract Article PDF–1.7M

Select item 433215019.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen

Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504

PMCID:: PMC4332150

Abstract Article PDF–2.8M

Select item 386272720.

Whole Exome Sequencing Identifies Novel Recurrently Mutated Genes in Patients with Splenic Marginal Zone Lymphoma

Marina Parry, Matthew J. J. Rose-Zerilli, Jane Gibson, Sarah Ennis, Renata Walewska, Jade Forster, Helen Parker, Zadie Davis, Anne Gardiner, Andrew Collins, David G. Oscier, Jonathan C. Strefford

PLoS One. 2013; 8(12): e83244. Published online 2013 Dec 13. doi: 10.1371/journal.pone.0083244

PMCID:: PMC3862727

Abstract Article PDF–256K

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