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Select item 81650301.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79879812.

Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders

Joseph J. Rossi, Jill A. Rosenfeld, Katie M. Chan, Haley Streff, Victoria Nankivell, Daniel J. Peet, Murray L. Whitelaw, David C. Bersten

Sci Rep. 2021; 11: 6602. Published online 2021 Mar 23. doi: 10.1038/s41598-021-86041-4

PMCID:: PMC7987981

Abstract Article PDF–2.2M

Select item 79622523.

The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex

Xin Wang, Wei Jiang, Shuo Luo, Xiaoyu Yang, Changnan Wang, Bingying Wang, Yongjun Dang, Yin Shen, Dengke K. Ma

Mol Brain. 2021; 14: 54. Published online 2021 Mar 16. doi: 10.1186/s13041-021-00767-w

PMCID:: PMC7962252

Abstract Article PDF–6.5M

Select item 69012784.

Neuronal PAS Domain Proteins 1 and 3 Are Master Regulators of Neuropsychiatric Risk Genes

Jacob J. Michaelson, Min-Kyoo Shin, Jin-Young Koh, Leo Brueggeman, Angela Zhang, Aaron Katzman, Latisha McDaniel, Mimi Fang, Miles Pufall, Andrew A. Pieper

Biol Psychiatry. Author manuscript; available in PMC 2019 Dec 9.

Published in final edited form as: Biol Psychiatry. 2017 Aug 1; 82(3): 213–223. Published online 2017 Apr 6. doi: 10.1016/j.biopsych.2017.03.021

PMCID:: PMC6901278

Abstract Article PDF–1.7M

Select item 62762165.

Molecular analysis of NPAS3 functional domains and variants

Leiah M. Luoma, Fred B. Berry

BMC Mol Biol. 2018; 19: 14. Published online 2018 Dec 3. doi: 10.1186/s12867-018-0117-4

PMCID:: PMC6276216

Abstract Article PDF–6.3M

Select item 53717306.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 51118847.

NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors

Dalei Wu, Xiaoyu Su, Nalini Potluri, Youngchang Kim, Fraydoon Rastinejad

eLife. 2016; 5: e18790. Published online 2016 Oct 26. doi: 10.7554/eLife.18790

PMCID:: PMC5111884

Abstract Article PDF–6.6M

Select item 44184788.

A genome-wide association meta-analysis of plasma Aß peptides concentrations in the elderly

V Chouraki, RFAG De Bruijn, J Chapuis, JC Bis, C Reitz, S Schraen, CA Ibrahim-Verbaas, B Grenier-Boley, C Delay, R Rogers, F Demiautte, A Mounier, AL Fitzpatrick, The Alzheimer’s Disease Neuroimaging Initiative, C Berr, J-F Dartigues, AG Uitterlinden, A Hofman, M Breteler, JT Becker, M Lathrop, N Schupf, A Alpérovitch, R Mayeux, CM van Duijn, L Buée, P Amouyel, OL Lopez, MA Ikram, C Tzourio, J-C Lambert

Mol Psychiatry. Author manuscript; available in PMC 2015 May 4.

Published in final edited form as: Mol Psychiatry. 2014 Dec; 19(12): 1326–1335. Published online 2014 Feb 18. doi: 10.1038/mp.2013.185

PMCID:: PMC4418478

Abstract Article PDF–1.0M

Select item 43321509.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen

Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504

PMCID:: PMC4332150

Abstract Article PDF–2.8M

Select item 399653710.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650

Correction in:: Nat Commun. 2023; 14: 569.

PMCID:: PMC3996537

Abstract Article PDF–1.9M

Select item 388055611.

Cross-Disorder Genomewide Analysis of Schizophrenia, Bipolar Disorder, and Depression

Jie Huang, Roy H. Perlis, Phil H. Lee, A John Rush, Maurizio Fava, Gary S. Sachs, Jeffrey Lieberman, Steven P. Hamilton, Patrick Sullivan, Pamela Sklar, Shaun Purcell, Jordan W. Smoller

Am J Psychiatry. Author manuscript; available in PMC 2014 Jan 4.

Published in final edited form as: Am J Psychiatry. 2010 Oct; 167(10): 10.1176/appi.ajp.2010.09091335. Published online 2010 Aug 16. doi: 10.1176/appi.ajp.2010.09091335

PMCID:: PMC3880556

Abstract Article PDF–404K

Select item 385466912.

Genome Wide Association Study (GWAS) of Chagas Cardiomyopathy in Trypanosoma cruzi Seropositive Subjects

Xutao Deng, Ester C. Sabino, Edecio Cunha-Neto, Antonio L. Ribeiro, Barbara Ianni, Charles Mady, Michael P. Busch, Mark Seielstad, the REDSII Chagas study group from the NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component

PLoS One. 2013; 8(11): e79629. Published online 2013 Nov 20. doi: 10.1371/journal.pone.0079629

PMCID:: PMC3854669

Abstract Article PDF–408K

Select item 382649313.

A fast-evolving human NPAS3 enhancer gained reporter expression in the developing forebrain of transgenic mice

Gretel B. Kamm, Rodrigo López-Leal, Juan R. Lorenzo, Lucía F. Franchini

Philos Trans R Soc Lond B Biol Sci. 2013 Dec 19; 368(1632): 20130019. doi: 10.1098/rstb.2013.0019

PMCID:: PMC3826493

Abstract Article PDF–1.8M

Select item 375340714.

A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci

David A. Hinds, George McMahon, Amy K. Kiefer, Chuong B. Do, Nicholas Eriksson, David M. Evans, Beate St Pourcain, Susan M. Ring, Joanna L. Mountain, Uta Francke, George Davey-Smith, Nicholas J. Timpson, Joyce Y. Tung

Nat Genet. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 907–911. Published online 2013 Jun 30. doi: 10.1038/ng.2686

PMCID:: PMC3753407

Article PDF–455K

Select item 367073415.

The Developmental Brain Gene NPAS3 Contains the Largest Number of Accelerated Regulatory Sequences in the Human Genome

Gretel B. Kamm, Francisco Pisciottano, Rafi Kliger, Lucía F. Franchini

Mol Biol Evol. 2013 May; 30(5): 1088–1102. Published online 2013 Feb 13. doi: 10.1093/molbev/mst023

PMCID:: PMC3670734

Abstract Article

Select item 357616016.

Expression of NPAS3 in the Human Cortex and Evidence of Its Posttranscriptional Regulation by miR-17 During Development, With Implications for Schizophrenia

Jenny Wong, Carlotta E. Duncan, Natalie J. Beveridge, Maree J. Webster, Murray J. Cairns, Cynthia Shannon Weickert

Schizophr Bull. 2013 Mar; 39(2): 396–406. Published online 2012 Jan 6. doi: 10.1093/schbul/sbr177

PMCID:: PMC3576160

Abstract Article PDF–5.5M

Select item 327569117.

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network (GOLDN)

Stella Aslibekyan, Edmond K. Kabagambe, Marguerite R. Irvin, Robert J. Straka, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jian Shen, Chao-Qiang Lai, Jose M. Ordovas, Donna K. Arnett

Pharmacogenet Genomics. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Pharmacogenet Genomics. 2012 Mar; 22(3): 191–197. doi: 10.1097/FPC.0b013e32834fdd41

PMCID:: PMC3275691

Abstract Article PDF–1.1M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312378519.

NPAS3 Demonstrates Features of a Tumor Suppressive Role in Driving the Progression of Astrocytomas

Frederico Moreira, Tim-Rasmus Kiehl, Kelvin So, Norbert F. Ajeawung, Carmelita Honculada, Peter Gould, Russell O. Pieper, Deepak Kamnasaran

Am J Pathol. 2011 Jul; 179(1): 462–476. doi: 10.1016/j.ajpath.2011.03.044

PMCID:: PMC3123785

Abstract Article PDF–2.0M

Select item 294516820.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

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