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Items: 1 to 20 of 75

1.
Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
Fei Xiong, Da Wang, Wei Xiong, Xin Wang, Wen-hua Huang, Guan-hua Wu, Wen-zheng Liu, Qi Wang, Jun-sheng Chen, Yi-yang Kuai, Bing Wang, Yong-jun Chen
J Exp Clin Cancer Res. 2024; 43: 152. Published online 2024 May 30. doi: 10.1186/s13046-024-03070-3
Correction in:
J Exp Clin Cancer Res. 2024; 43: 186.
PMCID:
PMC11137995
AbstractArticlePDF–20M
2.
Y chromosome damage underlies testicular abnormalities in ATR-X syndrome
Nayla Y. León, Thanh Nha Uyen Le, Andrew Garvie, Lee H. Wong, Stefan Bagheri-Fam, Vincent R. Harley
iScience. 2024 May 17; 27(5): 109629. Published online 2024 Mar 28. doi: 10.1016/j.isci.2024.109629
PMCID:
PMC11015497
AbstractArticlePDF–4.6M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
HP1 maintains protein stability of H3K9 methyltransferases and demethylases
Ryo Maeda, Makoto Tachibana
EMBO Rep. 2022 Apr; 23(4): e53581. Published online 2022 Feb 15. doi: 10.15252/embr.202153581
PMCID:
PMC8982598
AbstractArticlePDF–1.5M
5.
Targeting Cbx3/HP1γ Induces LEF-1 and IL-21R to Promote Tumor-Infiltrating CD8 T-Cell Persistence
Phuong T. Le, Ngoc Ha, Ngan K. Tran, Andrew G. Newman, Katharine M. Esselen, John L. Dalrymple, Eva M. Schmelz, Avinash Bhandoola, Hai-Hui Xue, Prim B. Singh, To-Ha Thai
Front Immunol. 2021; 12: 738958. Published online 2021 Oct 6. doi: 10.3389/fimmu.2021.738958
PMCID:
PMC8549513
AbstractArticlePDF–16M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Paulo P. Amaral, Pär G. Engström, Samuel C. Robson, Michael L. Nielsen, Tony Kouzarides, Gonçalo Castelo-Branco
Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 129–138. Published online 2019 May 9. doi: 10.1016/j.yexcr.2019.05.006
PMCID:
PMC6994247
AbstractArticlePDF–1.6M
8.
Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes
Ruby J Roach, Miguel Garavís, Carlos González, Geoffrey B Jameson, Vyacheslav V Filichev, Tracy K Hale
Nucleic Acids Res. 2020 Jan 24; 48(2): 682–693. Published online 2019 Dec 4. doi: 10.1093/nar/gkz1138
PMCID:
PMC6954420
AbstractArticlePDF–2.1M
9.
CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis
Giovanni Ligresti, Nunzia Caporarello, Jeffrey A. Meridew, Dakota L. Jones, Qi Tan, Kyoung Moo Choi, Andrew J. Haak, Aja Aravamudhan, Anja C. Roden, Y.S. Prakash, Gwen Lomberk, Raul A. Urrutia, Daniel J. Tschumperlin
JCI Insight. 2019 Jun 20; 4(12): e127111. Published online 2019 Jun 20. doi: 10.1172/jci.insight.127111
PMCID:
PMC6629126
AbstractArticlePDF–9.8M
10.
Aurora kinase B-phosphorylated HP1α functions in chromosomal instability
Monique M. Williams, Angela J. Mathison, Trent Christensen, Patricia T. Greipp, Darlene L. Knutson, Eric W. Klee, Michael T. Zimmermann, Juan Iovanna, Gwen A. Lomberk, Raul A. Urrutia
Cell Cycle. 2019; 18(12): 1407–1421. Published online 2019 May 26. doi: 10.1080/15384101.2019.1618126
PMCID:
PMC6592258
AbstractArticlePDF–5.8M
11.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
12.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
13.
KAP1 facilitates reinstatement of heterochromatin after DNA replication
Suk Min Jang, Annamaria Kauzlaric, Jean-Pierre Quivy, Julien Pontis, Benjamin Rauwel, Andrea Coluccio, Sandra Offner, Julien Duc, Priscilla Turelli, Geneviève Almouzni, Didier Trono
Nucleic Acids Res. 2018 Sep 28; 46(17): 8788–8802. Published online 2018 Jun 28. doi: 10.1093/nar/gky580
PMCID:
PMC6158507
AbstractArticlePDF–9.4M
14.
p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes
Valentina Rapisarda, Igor Malashchuk, Inemo E. Asamaowei, Krzysztof Poterlowicz, Michael Y. Fessing, Andrey A. Sharov, Iakowos Karakesisoglou, Vladimir A. Botchkarev, Andrei Mardaryev
J Invest Dermatol. 2017 Oct; 137(10): 2157–2167. doi: 10.1016/j.jid.2017.05.013
PMCID:
PMC5610935
AbstractArticle
15.
Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins
Meng Zhang, Dong Chen, Jing Xia, Wenqi Han, Xiekui Cui, Nils Neuenkirchen, Gretchen Hermes, Nenad Sestan, Haifan Lin
Genes Dev. 2017 Jul 1; 31(13): 1354–1369. doi: 10.1101/gad.298752.117
PMCID:
PMC5580656
AbstractArticlePDF–695K
16.
An HP1 isoform-specific feedback mechanism regulates Suv39h1 activity under stress conditions
Helena Raurell-Vila, Laia Bosch-Presegue, Jessica Gonzalez, Noriko Kane-Goldsmith, Carmen Casal, Jeremy P. Brown, Anna Marazuela-Duque, Prim B. Singh, Lourdes Serrano, Alejandro Vaquero
Epigenetics. 2017; 12(2): 166–175. Published online 2017 Jan 6. doi: 10.1080/15592294.2016.1278096
PMCID:
PMC5330444
AbstractArticlePDF–1.3M
17.
SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation
Benjamin L. Kidder, Gangqing Hu, Kairong Cui, Keji Zhao
Epigenetics Chromatin. 2017; 10: 8. Published online 2017 Feb 23. doi: 10.1186/s13072-017-0115-7
PMCID:
PMC5324308
AbstractArticlePDF–3.1M
18.
SCAI promotes DNA double-strand break repair in distinct chromosomal contexts
Rebecca Kring Hansen, Andreas Mund, Sara Lund Poulsen, Maria Sandoval, Karolin Klement, Katerina Tsouroula, Maxim A.X. Tollenaere, Markus Räschle, Rebeca Soria, Stefan Offermanns, Thomas Worzfeld, Robert Grosse, Dominique T. Brandt, Björn Rozell, Matthias Mann, Francesca Cole, Evi Soutoglou, Aaron A. Goodarzi, Jeremy A. Daniel, Niels Mailand, Simon Bekker-Jensen
Nat Cell Biol. Author manuscript; available in PMC 2017 Jun 1.
Published in final edited form as: Nat Cell Biol. 2016 Dec; 18(12): 1357–1366. Published online 2016 Nov 7. doi: 10.1038/ncb3436
PMCID:
PMC5278951
AbstractArticlePDF–2.1M
19.
Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome
Ronghui Li, Qiping Dong, Xinni Yuan, Xin Zeng, Yu Gao, Cassandra Chiao, Hongda Li, Xinyu Zhao, Sunduz Keles, Zefeng Wang, Qiang Chang
PLoS Genet. 2016 Jun; 12(6): e1006129. Published online 2016 Jun 28. doi: 10.1371/journal.pgen.1006129
PMCID:
PMC4924826
AbstractArticlePDF–1.9M
20.
Use of a Conditional Ubr5 Mutant Allele to Investigate the Role of an N-End Rule Ubiquitin-Protein Ligase in Hedgehog Signalling and Embryonic Limb Development
Elaine Kinsella, Natalie Dora, David Mellis, Laura Lettice, Paul Deveney, Robert Hill, Mark Ditzel
PLoS One. 2016; 11(6): e0157079. Published online 2016 Jun 14. doi: 10.1371/journal.pone.0157079
PMCID:
PMC4907512
AbstractArticlePDF–27M

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