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Items: 1 to 20 of 35

1.
The in vivo Interaction Landscape of Histones H3.1 and H3.3
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins
Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411
PMCID:
PMC9540345
AbstractArticlePDF–3.9M
2.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
3.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
4.
ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
Jie Li, Phillip M. Galbo, Jr., Weida Gong, Aaron J. Storey, Yi-Hsuan Tsai, Xufen Yu, Jeong Hyun Ahn, Yiran Guo, Samuel G. Mackintosh, Ricky D. Edmondson, Stephanie D. Byrum, Jason E. Farrar, Shenghui He, Ling Cai, Jian Jin, Alan J. Tackett, Deyou Zheng, Gang Greg Wang
Nat Commun. 2021; 12: 1045. Published online 2021 Feb 16. doi: 10.1038/s41467-021-21357-3
PMCID:
PMC7886901
AbstractArticlePDF–5.4M
5.
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer
Tiziano Bernasocchi, Geniver El Tekle, Marco Bolis, Azzurra Mutti, Arianna Vallerga, Laura P. Brandt, Filippo Spriano, Tanya Svinkina, Marita Zoma, Valentina Ceserani, Anna Rinaldi, Hana Janouskova, Daniela Bossi, Manuela Cavalli, Simone Mosole, Roger Geiger, Ze Dong, Cai-Guang Yang, Domenico Albino, Andrea Rinaldi, Peter Schraml, Simon Linder, Giuseppina M. Carbone, Andrea Alimonti, Francesco Bertoni, Holger Moch, Steven A. Carr, Wilbert Zwart, Marianna Kruithof-de Julio, Mark A. Rubin, Namrata D. Udeshi, Jean-Philippe P. Theurillat
Nat Commun. 2021; 12: 734. Published online 2021 Feb 2. doi: 10.1038/s41467-020-20820-x
PMCID:
PMC7854732
AbstractArticlePDF–4.5M
6.
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer
Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid, Isaac S. Harris, Bojana Jovanović, Katherine Murphy, Binbin Wang, Xintao Qiu, Jennifer E. Endress, Jaime Reyes, Klothilda Lim, Alba Font-Tello, Sudeepa Syamala, Tengfei Xiao, Chandra Sekhar Reddy Chilamakuri, Evangelia K. Papachristou, Clive D’Santos, Jayati Anand, Kunihiko Hinohara, Wei Li, Thomas O. McDonald, Adrienne Luoma, Rebecca J. Modiste, Quang-De Nguyen, Brittany Michel, Paloma Cejas, Cigall Kadoch, Jacob D. Jaffe, Kai W. Wucherpfennig, Jun Qi, X. Shirley Liu, Henry Long, Myles Brown, Jason S. Carroll, Joan S. Brugge, James Bradner, Franziska Michor, Kornelia Polyak
Mol Cell. Author manuscript; available in PMC 2021 Jun 18.
Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1096–1113.e8. Published online 2020 May 15. doi: 10.1016/j.molcel.2020.04.027
PMCID:
PMC7306005
AbstractArticlePDF–3.2M
7.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
8.
Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity
Rajesh Ponnusamy, Ritika Khatri, Paulo B. Correia, C. David Wood, Erika J. Mancini, Paul J. Farrell, Michelle J. West
PLoS Pathog. 2019 Jul; 15(7): e1007458. Published online 2019 Jul 8. doi: 10.1371/journal.ppat.1007458
PMCID:
PMC6638984
AbstractArticlePDF–2.8M
9.
The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species
Ali Zhang, Tanner M. Tessier, Kristianne J. C. Galpin, Cason R. King, Steven F. Gameiro, Wyatt W. Anderson, Ahmed F. Yousef, Wen T. Qin, Shawn S. C. Li, Joe S. Mymryk
Viruses. 2018 Dec; 10(12): 662. Published online 2018 Nov 22. doi: 10.3390/v10120662
PMCID:
PMC6315623
AbstractArticlePDF–4.0M
10.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
11.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
12.
The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery
Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries, Alfred C. O. Vertegaal
Nat Commun. 2017; 8: 1809. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01900-x
PMCID:
PMC5703878
AbstractArticlePDF–3.7M
13.
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2
Joshua P. Plotnik, Peter C. Hollenhorst
Nucleic Acids Res. 2017 May 5; 45(8): 4452–4462. Published online 2017 Jan 24. doi: 10.1093/nar/gkx039
PMCID:
PMC5416753
AbstractArticlePDF–2.9M
14.
A de novo missense mutation in ZMYND11 is associated with global developmental delay, seizures, and hypotonia
Abby M. Moskowitz, Newell Belnap, Ashley L. Siniard, Szabolcs Szelinger, Ana M. Claasen, Ryan F. Richholt, Matt De Both, Jason J. Corneveaux, Chris Balak, Ignazio S. Piras, Megan Russell, Amanda L. Courtright, Sampath Rangasamy, Keri Ramsey, David W. Craig, Vinodh Narayanan, Matt J. Huentelman, Isabelle Schrauwen
Cold Spring Harb Mol Case Stud. 2016 Sep; 2(5): a000851. doi: 10.1101/mcs.a000851
PMCID:
PMC5002929
AbstractArticlePDF–1.0M
15.
Selective Recognition of H3.1K36 Dimethylation/H4K16 Acetylation Facilitates the Regulation of All-trans-retinoic Acid (ATRA)-responsive Genes by Putative Chromatin Reader ZMYND8
Santanu Adhikary, Sulagna Sanyal, Moitri Basu, Isha Sengupta, Sabyasachi Sen, Dushyant Kumar Srivastava, Siddhartha Roy, Chandrima Das
J Biol Chem. 2016 Feb 5; 291(6): 2664–2681. Published online 2015 Dec 11. doi: 10.1074/jbc.M115.679985
PMCID:
PMC4742736
AbstractArticlePDF–4.5M
16.
BS69/ZMYND11 C-Terminal Domains Bind and Inhibit EBNA2
Matthew R. Harter, Cheng-Der Liu, Chih-Lung Shen, Elsie Gonzalez-Hurtado, Zhi-Min Zhang, Muyu Xu, Ernest Martinez, Chih-Wen Peng, Jikui Song
PLoS Pathog. 2016 Feb; 12(2): e1005414. Published online 2016 Feb 4. doi: 10.1371/journal.ppat.1005414
PMCID:
PMC4742278
AbstractArticlePDF–4.2M
17.
BS69/ZMYND11 Reads and Connects Histone H3.3 Lysine 36 Trimethylation Decorated Chromatin to Regulated Pre-mRNA Processing
Rui Guo, Lijuan Zheng, Juw Won Park, Ruitu Lv, Hao Chen, Fangfang Jiao, Wenqi Xu, Shi-Rong Mu, Hong Wen, Jinsong Qiu, Zhentian Wang, Pengyuan Yang, Feizhen Wu, Jingyi Hui, Xiangdong Fu, Xiaobing Shi, Yujiang Geno Shi
Mol Cell. Author manuscript; available in PMC 2015 Oct 23.
Published in final edited form as: Mol Cell. 2014 Oct 23; 56(2): 298–310. Published online 2014 Sep 25. doi: 10.1016/j.molcel.2014.08.022
PMCID:
PMC4363072
AbstractArticlePDF–1.1M
18.
Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination
Fade Gong, Li-Ya Chiu, Ben Cox, François Aymard, Thomas Clouaire, Justin W. Leung, Michael Cammarata, Mercedes Perez, Poonam Agarwal, Jennifer S. Brodbelt, Gaëlle Legube, Kyle M. Miller
Genes Dev. 2015 Jan 15; 29(2): 197–211. doi: 10.1101/gad.252189.114
PMCID:
PMC4298138
AbstractArticlePDF–2.5M
19.
Refining analyses of copy number variation identifies specific genes associated with developmental delay
Bradley P. Coe, Kali Witherspoon, Jill A. Rosenfeld, Bregje W.M. van Bon, Anneke T. Vulto-van Silfhout, Paolo Bosco, Kathryn L. Friend, Carl Baker, Serafino Buono, Lisenka E.L.M. Vissers, Janneke H. Schuurs-Hoeijmakers, Alex Hoischen, Rolph Pfundt, Nik Krumm, Gemma L. Carvill, Deana Li, David Amaral, Natasha Brown, Paul J. Lockhart, Ingrid E Scheffer, Antonino Alberti, Marie Shaw, Rosa Pettinato, Raymond Tervo, Nicole de Leeuw, Margot R.F. Reijnders, Beth S. Torchia, Hilde Peeters, Brian J. O'Roak, Marco Fichera, Jayne Y. Hehir-Kwa, Jay Shendure, Heather C. Mefford, Eric Haan, Jozef Gécz, Bert B.A. de Vries, Corrado Romano, Evan E. Eichler
Nat Genet. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: Nat Genet. 2014 Oct; 46(10): 1063–1071. Published online 2014 Sep 14. doi: 10.1038/ng.3092
PMCID:
PMC4177294
AbstractArticlePDF–806K
20.
ZMYND11 links histone H3.3 K36 trimethylation to transcription elongation and tumor suppression
Hong Wen, Yuanyuan Li, Yuanxin Xi, Shiming Jiang, Sabrina Stratton, Danni Peng, Kaori Tanaka, Yongfeng Ren, Zheng Xia, Jun Wu, Bing Li, Michelle C. Barton, Wei Li, Haitao Li, Xiaobing Shi
Nature. Author manuscript; available in PMC 2014 Oct 10.
Published in final edited form as: Nature. 2014 Apr 10; 508(7495): 263–268. Published online 2014 Mar 2. doi: 10.1038/nature13045
PMCID:
PMC4142212
AbstractArticlePDF–2.5M

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