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Select item 103342841.

Targeting soluble epoxide hydrolase promotes osteogenic–angiogenic coupling via activating SLIT3/HIF‐1α signalling pathway

Lu Gao, Weixian Chen, Lijun Li, Juanjuan Li, Wenyao Kongling, Yaoyang Zhang, Xueping Yang, Yanrong Zhao, Jie Bai, Fu Wang

Cell Prolif. 2023 Jul; 56(7): e13403. Published online 2023 Jan 13. doi: 10.1111/cpr.13403

PMCID:: PMC10334284

Abstract Article PDF–11M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 92792853.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 82991944.

Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma

Ke Zhan, Yang Bai, Shengtao Liao, Hongyu Chen, Lili Kuang, Qingqing Luo, Lin Lv, Liewang Qiu, Zhechuan Mei

Mol Med Rep. 2021 Sep; 24(3): 650. Published online 2021 Jul 13. doi: 10.3892/mmr.2021.12289

PMCID:: PMC8299194

Abstract Article PDF–2.3M

Select item 81215835.

Association of rs11780592 Polymorphism in the Human Soluble Epoxide Hydrolase Gene (EPHX2) with Oxidized LDL and Mortality in Patients with Diabetic Chronic Kidney Disease

Stefanos Roumeliotis, Athanasios Roumeliotis, Aikaterini Stamou, Stylianos Panagoutsos, Vangelis G. Manolopoulos, Fotis Tsetsos, Marianthi Georgitsi, Vassilios Liakopoulos

Oxid Med Cell Longev. 2021; 2021: 8817502. Published online 2021 May 6. doi: 10.1155/2021/8817502

PMCID:: PMC8121583

Abstract Article PDF–482K

Select item 78811126.

Preservation of epoxyeicosatrienoic acid bioavailability prevents renal allograft dysfunction and cardiovascular alterations in kidney transplant recipients

Thomas Duflot, Charlotte Laurent, Anne Soudey, Xavier Fonrose, Mouad Hamzaoui, Michèle Iacob, Dominique Bertrand, Julie Favre, Isabelle Etienne, Clothilde Roche, David Coquerel, Maëlle Le Besnerais, Safa Louhichi, Tracy Tarlet, Dongyang Li, Valéry Brunel, Christophe Morisseau, Vincent Richard, Robinson Joannidès, Françoise Stanke-Labesque, Fabien Lamoureux, Dominique Guerrot, Jérémy Bellien

Sci Rep. 2021; 11: 3739. Published online 2021 Feb 12. doi: 10.1038/s41598-021-83274-1

PMCID:: PMC7881112

Abstract Article PDF–3.6M

Select item 78318217.

Clinical significance of EPHX2 deregulation in prostate cancer

Ming-Sheng Liu, Hui Zhao, Chen-Xiang Xu, Ping-Bo Xie, Wei Wang, Ying-Yu Yang, Wen-Hui Lee, Yang Jin, Hong-Qing Zhou

Asian J Androl. 2021 Jan-Feb; 23(1): 109–115. Published online 2020 Jul 17. doi: 10.4103/aja.aja_34_20

PMCID:: PMC7831821

Abstract Article PDF–1.8M

Select item 77926128.

The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease

Jérémie Gautheron, Isabelle Jéru

Int J Mol Sci. 2021 Jan; 22(1): 13. Published online 2020 Dec 22. doi: 10.3390/ijms22010013

PMCID:: PMC7792612

Abstract Article PDF–1.0M

Select item 76696609.

Soluble epoxide hydrolase as a therapeutic target for obesity-induced disorders: roles of gut barrier function involved

Jianan Zhang, Maolin Tu, Zhenhua Liu, Guodong Zhang

Prostaglandins Leukot Essent Fatty Acids. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2020 Nov; 162: 102180. Published online 2020 Sep 19. doi: 10.1016/j.plefa.2020.102180

PMCID:: PMC7669660

Abstract Article PDF–739K

Select item 683185110.

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis

Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu

iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057

PMCID:: PMC6831851

Abstract Article PDF–9.8M

Select item 667298411.

Polymorphisms in the Human Soluble Epoxide Hydrolase Gene EPHX2 Linked to Neuronal Survival after Ischemic Injury

Ines P. Koerner, Rachel Jacks, Andrea E. DeBarber, Dennis Koop, Peizhong Mao, David F. Grant, Nabil J. Alkayed

J Neurosci. 2007 Apr 25; 27(17): 4642–4649. doi: 10.1523/JNEUROSCI.0056-07.2007

PMCID:: PMC6672984

Abstract Article PDF–382K

Select item 616214712.

Association between the EPHX2 p.Lys55Arg Polymorphism and Prognosis Following an Acute Coronary Syndrome

Akinyemi Oni-Orisan, Sharon Cresci, Philip G. Jones, Katherine N. Theken, John A. Spertus, Craig R. Lee

Prostaglandins Other Lipid Mediat. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Prostaglandins Other Lipid Mediat. 2018 Sep; 138: 15–22. Published online 2018 Aug 7. doi: 10.1016/j.prostaglandins.2018.07.005

PMCID:: PMC6162147

Abstract Article PDF–1.1M

Select item 586483213.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 583217914.

Association of EPHX2 R287Q Polymorphism with Diabetic Nephropathy in Chinese Type 2 Diabetic Patients

Liang Ma, Meihua Yan, Xiaomu Kong, Yongwei Jiang, Tingting Zhao, Hailing Zhao, Qian Liu, Haojun Zhang, Peng Liu, Yongtong Cao, Ping Li

J Diabetes Res. 2018; 2018: 2786470. Published online 2018 Feb 5. doi: 10.1155/2018/2786470

PMCID:: PMC5832179

Abstract Article PDF–656K

Select item 577698915.

Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation

Yang-Ming Yang, Dong Sun, Sharath Kandhi, Ghezal Froogh, Jian Zhuge, Weihua Huang, Bruce D. Hammock, An Huang

Proc Natl Acad Sci U S A. 2018 Jan 16; 115(3): 613–618. Published online 2018 Jan 2. doi: 10.1073/pnas.1716016115

PMCID:: PMC5776989

Abstract Article PDF–1.6M

Select item 577504316.

Chemical proteomics reveals soluble epoxide hydrolase as a therapeutic target for ocular neovascularization

Rania S. Sulaiman, Bomina Park, Sardar Pasha Sheik Pran Babu, Yubing Si, Rakshin Kharwadkar, Sayak K. Mitter, Bit Lee, Wei Sun, Xiaoping Qi, Michael E. Boulton, Samy Meroueh, Xiang Fei, Seung-Yong Seo, Timothy W. Corson

ACS Chem Biol. Author manuscript; available in PMC 2019 Jan 19.

Published in final edited form as: ACS Chem Biol. 2018 Jan 19; 13(1): 45–52. Published online 2017 Dec 1. doi: 10.1021/acschembio.7b00854