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Select item 112230801.

Hierarchical and scaffolded phosphorylation of two degrons controls PER2 stability

Joel Celio Francisco, David M. Virshup

J Biol Chem. 2024 Jun; 300(6): 107391. Published online 2024 May 20. doi: 10.1016/j.jbc.2024.107391

PMCID:: PMC11223080

Abstract Article PDF–1.6M

Select item 111617562.

Phosphorylation of DNA-binding domains of CLOCK–BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells

Yuta Otobe, Eui Min Jeong, Shunsuke Ito, Yuta Shinohara, Nobuhiro Kurabayashi, Atsu Aiba, Yoshitaka Fukada, Jae Kyoung Kim, Hikari Yoshitane

Proc Natl Acad Sci U S A. 2024 Jun 4; 121(23): e2316858121. Published online 2024 May 28. doi: 10.1073/pnas.2316858121

PMCID:: PMC11161756

Abstract Article PDF–4.4M

Select item 111130943.

Nucleolar localization and circadian regulation of Per2S, a novel splicing variant of the Period 2 gene

Daniele Avitabile, Licia Genovese, Donatella Ponti, Danilo Ranieri, Salvatore Raffa, Antonella Calogero, Maria Rosaria Torrisi

Cell Mol Life Sci. 2014 Jul; 71(13): 2547–2559. Published online 2013 Nov 8. doi: 10.1007/s00018-013-1503-1

PMCID:: PMC11113094

Abstract Article PDF–1.5M

Select item 107883434.

Importance of Per2 in cardiac mitochondrial protection during stress

Meghana Bhaskara, Olufisayo Anjorin, Arris Yoniles, Jianyun Liu, Meijing Wang

Sci Rep. 2024; 14: 1290. Published online 2024 Jan 14. doi: 10.1038/s41598-024-51799-w

PMCID:: PMC10788343

Abstract Article PDF–1.6M

Select item 106268275.

PER2 binding to HSP90 enhances immune response against oral squamous cell carcinoma by inhibiting IKK/NF-κB pathway and PD-L1 expression

Zhiwei Zhang, Deping Sun, Hong Tang, Jie Ren, Shilin Yin, Kai Yang

J Immunother Cancer. 2023; 11(11): e007627. Published online 2023 Nov 1. doi: 10.1136/jitc-2023-007627

PMCID:: PMC10626827

Abstract Article PDF–12M

Select item 105314026.

A Three-Way Interaction of Sex, PER2 rs56013859 Polymorphism, and Family Maltreatment in Depressive Symptoms in Adolescents

Catalina Torres Soler, Sofia H. Kanders, Mattias Rehn, Susanne Olofsdotter, Cecilia Åslund, Kent W. Nilsson

Genes (Basel) 2023 Sep; 14(9): 1723. Published online 2023 Aug 29. doi: 10.3390/genes14091723

PMCID:: PMC10531402

Abstract Article PDF–1.1M

Select item 103417167.

PER2 Promotes Odontoblastic/Osteogenic Differentiation of Dental Pulp Stem Cells by Modulating Mitochondrial Metabolism

Wushuang Huang, Qi Huang, Hongwen He, Fang Huang

Int J Mol Sci. 2023 Jul; 24(13): 10661. Published online 2023 Jun 26. doi: 10.3390/ijms241310661

PMCID:: PMC10341716

Abstract Article PDF–6.2M

Select item 101968258.

PER2 integrates circadian disruption and pituitary tumorigenesis

Lianxia Guo, Haobin Cen, Jiaxian Weng, Yiting He, Xiaocao Guo, Di He, Kaisheng Liu, Shuyi Duan, Jing Yang, Xiaojian Zhang, Zifei Qin, Yong Wan, Zhiyong Chen, Baojian Wu

Theranostics. 2023; 13(8): 2657–2672. Published online 2023 Apr 29. doi: 10.7150/thno.82995

PMCID:: PMC10196825

Abstract Article PDF–7.5M

Select item 100018529.

Relationship between APOE, PER2, PER3 and OX2R Genetic Variants and Neuropsychiatric Symptoms in Patients with Alzheimer’s Disease

Susana Lozano-Tovar, Yaneth Rodríguez-Agudelo, David José Dávila-Ortiz de Montellano, Blanca Estela Pérez-Aldana, Alberto Ortega-Vázquez, Nancy Monroy-Jaramillo

Int J Environ Res Public Health. 2023 Mar; 20(5): 4412. Published online 2023 Mar 1. doi: 10.3390/ijerph20054412

PMCID:: PMC10001852

Abstract Article PDF–1.5M

Select item 927597410.

Circadian Period 2 (Per2) downregulate inhibitor of differentiation 3 (Id3) expression via PTEN/AKT/Smad5 axis to inhibits glioma cell proliferation

Yifan Zhang, Xvlei Hu, Hailiang Li, Jian Yao, Ping Yang, Yuanxiang Lan, Hechun Xia

Bioengineered. 2022; 13(5): 12350–12364. Published online 2022 May 21. doi: 10.1080/21655979.2022.2074107

PMCID:: PMC9275974

Abstract Article PDF–14M

Select item 926261411.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 835513412.

Targeting circadian PER2 as therapy in myocardial ischemia and reperfusion injury

Yoshimasa Oyama, Lori Walker, Tobias Eckle

Chronobiol Int. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Chronobiol Int. 2021 Sep; 38(9): 1262–1273. Published online 2021 May 25. doi: 10.1080/07420528.2021.1928160

Correction in:: Chronobiol Int. 2021 Oct 11 : 1.

PMCID:: PMC8355134

Abstract Article PDF–730K

Select item 831929013.

Expression of HO1 and PER2 can predict the incidence of delirium in trauma patients with concomitant brain injury

Matti Steimer, Sandra Kaiser, Felix Ulbrich, Johannes Kalbhenn, Hartmut Bürkle, Nils Schallner

Sci Rep. 2021; 11: 15388. Published online 2021 Jul 28. doi: 10.1038/s41598-021-94773-6

PMCID:: PMC8319290

Abstract Article PDF–1.6M

Select item 829513214.

Dopamine adjusts the circadian gene expression of Per2 and Per3 in human dermal fibroblasts from ADHD patients

Frank Faltraco, Denise Palm, Adriana Uzoni, Lena Borchert, Frederick Simon, Oliver Tucha, Johannes Thome

J Neural Transm (Vienna) 2021; 128(7): 1135–1145. Published online 2021 Jul 18. doi: 10.1007/s00702-021-02374-4

PMCID:: PMC8295132

Abstract Article PDF–1.1M

Select item 827790515.

Differential effects of SUMO1 and SUMO2 on circadian protein PER2 stability and function

Ling-Chih Chen, Yung-Lin Hsieh, Grace Y. T. Tan, Tai-Yun Kuo, Yu-Chi Chou, Pang-Hung Hsu, Wendy W. Hwang-Verslues

Sci Rep. 2021; 11: 14431. Published online 2021 Jul 13. doi: 10.1038/s41598-021-93933-y

PMCID:: PMC8277905

Abstract Article PDF–2.3M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 803884617.

Phosphorylation of GAPVD1 Is Regulated by the PER Complex and Linked to GAPVD1 Degradation

Hussam Ibrahim, Philipp Reus, Anna Katharina Mundorf, Anna-Lena Grothoff, Valerie Rudenko, Christina Buschhaus, Anja Stefanski, Niklas Berleth, Björn Stork, Kai Stühler, Faiza Kalfalah, Hans Reinke

Int J Mol Sci. 2021 Apr; 22(7): 3787. Published online 2021 Apr 6. doi: 10.3390/ijms22073787