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Select item 111718011.

Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry

Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J. Gibbings, Laura Trinkle-Mulcahy, John W. Copeland

Int J Mol Sci. 2024 Jun; 25(11): 5686. Published online 2024 May 23. doi: 10.3390/ijms25115686

PMCID:: PMC11171801

Abstract Article PDF–3.1M

Select item 104805352.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 102841173.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100729065.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 100621236.

KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle

Danielle L. Chappell, Praneet K. Sandhu, Jason P. Wong, Aadra P. Bhatt, Xiaoxi Liu, Sara J. Buhrlage, Brenda R. S. Temple, M. Ben Major, Blossom Damania

J Virol. 2023 Mar; 97(3): e01763-22. Published online 2023 Mar 6. doi: 10.1128/jvi.01763-22

PMCID:: PMC10062123

Abstract Article PDF–2.7M

Select item 100226867.

Myosin-X recruits lamellipodin to filopodia tips

Ana Popović, Mitro Miihkinen, Sujan Ghimire, Rafael Saup, Max L. B. Grönloh, Neil J. Ball, Benjamin T. Goult, Johanna Ivaska, Guillaume Jacquemet

J Cell Sci. 2023 Mar 1; 136(5): jcs260574. Published online 2023 Mar 2. doi: 10.1242/jcs.260574

PMCID:: PMC10022686

Abstract Article

Select item 97725588.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 97696989.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 952364510.

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis

Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han

Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6

PMCID:: PMC9523645

Abstract Article PDF–3.9M

Select item 948193311.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 945258712.

PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP_L to promote TNFα-mediated cell death

Guowei Wu, Dekang Li, Wei Liang, Weimin Sun, Xingxing Xie, Yilun Tong, Bing Shan, Mengmeng Zhang, Xiaojuan Lu, Junying Yuan, Ying Li

Cell Death Dis. 2022 Sep; 13(9): 773. Published online 2022 Sep 7. doi: 10.1038/s41419-022-05206-9

PMCID:: PMC9452587

Abstract Article PDF–5.5M

Select item 928853613.

Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1

Yonggang Zou, Qi Zheng, Bin Jiang, Yuning Liu, Yanhua Xu, Liang Ma, Zonghao Hu, Ming Wu, Hai Song

Cell Death Dis. 2022 Jul; 13(7): 618. Published online 2022 Jul 16. doi: 10.1038/s41419-022-05076-1

PMCID:: PMC9288536

Abstract Article PDF–5.1M

Select item 927928514.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 926085615.

FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability

Nikol Dibus, Vladimir Korinek, Lukas Cermak

Front Cell Dev Biol. 2022; 10: 929288. Published online 2022 Jun 23. doi: 10.3389/fcell.2022.929288

Correction in:: Front Cell Dev Biol. 2022; 10: 1000878.

PMCID:: PMC9260856

Abstract Article PDF–2.8M

Select item 917796516.

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition

Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O’Brien, Xiaozhe Xiong, Carino Gurjao, Maximilien Grandclaudon, Srivatsan Raghavan, Steven M. Corsello, Steven A. Carr, Namrata D. Udeshi, James Berstler, Ewa Sicinska, Kimmie Ng, Marios Giannakis

Nat Commun. 2022; 13: 3181. Published online 2022 Jun 8. doi: 10.1038/s41467-022-30794-7

PMCID:: PMC9177965

Abstract Article PDF–2.2M

Select item 911973617.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910523518.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151