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Select item 112200281.

The circadian gene ARNTL2 promotes nasopharyngeal carcinoma invasiveness and metastasis through suppressing AMOTL2-LATS-YAP pathway

Wenqing Zou, Yiming Lei, Cong Ding, Hongjun Xiao, Shunxin Wang, Shaobo Liang, Weijie Luo, Zhiqing Long, Shiwei He, Qingjie Li, Han Qiao, Na Liu, Yanping Mao

Cell Death Dis. 2024 Jul; 15(7): 466. Published online 2024 Jul 2. doi: 10.1038/s41419-024-06860-x

PMCID:: PMC11220028

Abstract Article PDF–8.2M

Select item 112084522.

BMAL2 promotes eCIRP-induced macrophage endotoxin tolerance

Mian Zhou, Monowar Aziz, Jingsong Li, Alok Jha, Gaifeng Ma, Atsushi Murao, Ping Wang

Front Immunol. 2024; 15: 1426682. Published online 2024 Jun 13. doi: 10.3389/fimmu.2024.1426682

PMCID:: PMC11208452

Abstract Article PDF–2.3M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80459324.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 74431435.

ARNTL2 promotes pancreatic ductal adenocarcinoma progression through TGF/BETA pathway and is regulated by miR-26a-5p

Zhifang Wang, Tingting Liu, Wenhua Xue, Yuanyuan Fang, Xiaolong Chen, Lijun Xu, Lixia Zhang, Kelei Guan, Juntao Pan, Lili Zheng, Guijun Qin, Tingting Wang

Cell Death Dis. 2020 Aug; 11(8): 692. Published online 2020 Aug 10. doi: 10.1038/s41419-020-02839-6

PMCID:: PMC7443143

Abstract Article PDF–5.8M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67722807.

The Basic Helix-Loop-Helix-PAS Protein MOP9 Is a Brain-Specific Heterodimeric Partner of Circadian and Hypoxia Factors

John B. Hogenesch, Yi-Zhong Gu, Susan M. Moran, Kazuhiro Shimomura, Laurel A. Radcliffe, Joseph S. Takahashi, Christopher A. Bradfield

J Neurosci. 2000 Jul 1; 20(13): RC83. doi: 10.1523/JNEUROSCI.20-13-j0002.2000

PMCID:: PMC6772280

Abstract PDF–345K

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 48641249.

An Arntl2-driven secretome enables lung adenocarcinoma metastatic self-sufficiency

Jennifer J. Brady, Chen-Hua Chuang, Peyton G. Greenside, Zoë N. Rogers, Christopher W. Murray, Deborah R. Caswell, Ursula Hartmann, Andrew J. Connolly, E. Alejandro Sweet-Cordero, Anshul Kundaje, Monte M. Winslow

Cancer Cell. Author manuscript; available in PMC 2017 May 9.

Published in final edited form as: Cancer Cell. 2016 May 9; 29(5): 697–710. Published online 2016 Apr 14. doi: 10.1016/j.ccell.2016.03.003

PMCID:: PMC4864124

Abstract Article PDF–2.0M

Select item 458732210.

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage

Romain Drissi, Marie-Line Dubois, Mélanie Douziech, François-Michel Boisvert

Mol Cell Proteomics. 2015 Jul; 14(7): 2002–2013. Published online 2015 May 11. doi: 10.1074/mcp.M115.048991

PMCID:: PMC4587322

Abstract Article PDF–3.0M

Select item 434823611.

Ube3a Imprinting Impairs Circadian Robustness in Angelman Syndrome Models

Shu-qun Shi, Terry Jo Bichell, Rebecca A. Ihrie, Carl Hirschie Johnson

Curr Biol. Author manuscript; available in PMC 2016 Mar 2.

Published in final edited form as: Curr Biol. 2015 Mar 2; 25(5): 537–545. Published online 2015 Feb 5. doi: 10.1016/j.cub.2014.12.047

PMCID:: PMC4348236

Abstract Article PDF–1010K

Select item 432075912.

Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures

Michael J Parsons, Kathryn J Lester, Nicola L Barclay, Simon N Archer, Patrick M Nolan, Thalia C Eley, Alice M Gregory

J Sleep Res. 2014 Oct; 23(5): 595–604. Published online 2014 Mar 17. doi: 10.1111/jsr.12144

PMCID:: PMC4320759

Abstract Article PDF–322K

Select item 399653713.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650

Correction in:: Nat Commun. 2023; 14: 569.

PMCID:: PMC3996537

Abstract Article PDF–1.9M

Select item 381740414.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat

Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54

PMCID:: PMC3817404

Abstract Article PDF–13M

Select item 361082015.

Dynamic Circadian Protein–Protein Interaction Networks Predict Temporal Organization of Cellular Functions

Thomas Wallach, Katja Schellenberg, Bert Maier, Ravi Kiran Reddy Kalathur, Pablo Porras, Erich E. Wanker, Matthias E. Futschik, Achim Kramer

PLoS Genet. 2013 Mar; 9(3): e1003398. Published online 2013 Mar 28. doi: 10.1371/journal.pgen.1003398

PMCID:: PMC3610820

Abstract Article PDF–6.3M

Select item 340189916.

Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia

Hader A Mansour, Michael E Talkowski, Joel Wood, Kodavali V Chowdari, Lora McClain, Konasale Prasad, Debra Montrose, Andrea Fagiolini, Edward S Friedman, Michael H Allen, Charles L Bowden, Joseph Calabrese, Rif S El-Mallakh, Michael Escamilla, Stephen V Faraone, Mark D Fossey, Laszlo Gyulai, Jennifer M Loftis, Peter Hauser, Terence A Ketter, Lauren B Marangell, David J Miklowitz, Andrew A Nierenberg, Jayendra Patel, Gary S Sachs, Pamela Sklar, Jordan W Smoller, Nan Laird, Matcheri Keshavan, Michael E Thase, David Axelson, Boris Birmaher, David Lewis, Tim Monk, Ellen Frank, David J Kupfer, Bernie Devlin, Vishwajit L Nimgaonkar

Bipolar Disord. Author manuscript; available in PMC 2012 Jul 23.

Published in final edited form as: Bipolar Disord. 2009 Nov; 11(7): 701–710. doi: 10.1111/j.1399-5618.2009.00756.x

PMCID:: PMC3401899

Abstract Article PDF–305K

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 305533718.

Differential Association of Circadian Genes with Mood Disorders: CRY1 and NPAS2 are Associated with Unipolar Major Depression and CLOCK and VIP with Bipolar Disorder

Virginia Soria, Èrika Martínez-Amorós, Geòrgia Escaramís, Joaquín Valero, Rosario Pérez-Egea, Cecilia García, Alfonso Gutiérrez-Zotes, Dolors Puigdemont, Mònica Bayés, José M Crespo, Lourdes Martorell, Elisabet Vilella, Antonio Labad, Julio Vallejo, Víctor Pérez, José M Menchón, Xavier Estivill, Mònica Gratacòs, Mikel Urretavizcaya

Neuropsychopharmacology. 2010 May; 35(6): 1279–1289. Published online 2010 Jan 13. doi: 10.1038/npp.2009.230

PMCID:: PMC3055337

Abstract Article PDF–415K

Select item 294516819.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 285410620.

Louise K Sjöholm, Leena Kovanen, Sirkku T Saarikoski, Martin Schalling, Catharina Lavebratt, Timo Partonen

J Circadian Rhythms. 2010; 8: 1. Published online 2010 Jan 21. doi: 10.1186/1740-3391-8-1

PMCID:: PMC2854106

Abstract Article PDF–288K

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