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Select item 107854881.

Downregulation of PTPRT elevates the expression of survivin and promotes the proliferation, migration, and invasion of lung adenocarcinoma

Chao Chen, Haozhen Liu, Yanling Li, Qumiao Xu, Jixian Liu

BMC Cancer. 2024; 24: 63. Published online 2024 Jan 12. doi: 10.1186/s12885-024-11840-7

PMCID:: PMC10785488

Abstract Article PDF–4.4M

Select item 92504382.

Association of PTPRT Mutations with Cancer Metastasis in Multiple Cancer Types

Chao Chen, Haozhen Liu, Qumiao Xu, Xiuqing Zhang, Feng Mu, Jixian Liu

Biomed Res Int. 2022; 2022: 9386477. Published online 2022 Jun 25. doi: 10.1155/2022/9386477

PMCID:: PMC9250438

Abstract Article PDF–1.8M

Select item 85229743.

A Novel de Novo 20q13.11q13.12 Microdeletion in a Boy with Neurodevelopmental Disorders − Case Report

Joanna Bernaciak, Barbara Wiśniowiecka-Kowalnik, Jennifer Castañeda, Anna Kutkowska-Kaźmierczak, Beata Nowakowska

Dev Period Med. 2017 Jun; 21(2): 91–94. Published online 2017 Aug 11. doi: 10.34763/devperiodmed.20172102.9194

PMCID:: PMC8522974

Abstract Article PDF–339K

Select item 83708174.

PTPRT Could Be a Treatment Predictive and Prognostic Biomarker for Breast Cancer

Lun Li, Feng Xu, Pingfang Xie, Liqin Yuan, Meirong Zhou

Biomed Res Int. 2021; 2021: 3301402. Published online 2021 Aug 10. doi: 10.1155/2021/3301402

PMCID:: PMC8370817

Abstract Article PDF–4.5M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75743786.

PTPRT epigenetic silencing defines lung cancer with STAT3 activation and can direct STAT3 targeted therapies

Malabika Sen, Audrey Kindsfather, Ludmila Danilova, Feng Zhang, Raffaele Colombo, Matthew G. LaPorte, Brenda F. Kurland, Donna M. Huryn, Peter Wipf, James G. Herman

Epigenetics. 2020; 15(6-7): 604–617. Published online 2019 Oct 13. doi: 10.1080/15592294.2019.1676597

PMCID:: PMC7574378

Abstract Article PDF–3.5M

Select item 70501037.

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair

Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen

Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794

PMCID:: PMC7050103

Abstract Article PDF–1.8M

Select item 69157838.

Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans

Khadijah A. Mitchell, Noah Nichols, Wei Tang, Jennifer Walling, Holly Stevenson, Marbin Pineda, Roxana Stefanescu, Daniel C. Edelman, Andrew T. Girvin, Adriana Zingone, Sanju Sinha, Elise Bowman, Emily L. Rossi, Rony F. Arauz, Yuelin Jack Zhu, Justin Lack, Elizabeth Weingartner, Josh Waterfall, Sharon R. Pine, John Simmons, Paul Meltzer, Bríd M. Ryan

Nat Commun. 2019; 10: 5735. Published online 2019 Dec 16. doi: 10.1038/s41467-019-13732-y

Correction in:: Nat Commun. 2020; 11: 700.

PMCID:: PMC6915783

Abstract Article PDF–1.6M

Select item 56634659.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

Select item 465185110.

Frequent promoter hypermethylation of PTPRT increases STAT3 activation and sensitivity to STAT3 inhibition in head and neck cancer

Noah D. Peyser, Maria Freilino, Lin Wang, Yan Zeng, Hua Li, Daniel E. Johnson, Jennifer R. Grandis

Oncogene. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Oncogene. 2016 Mar 3; 35(9): 1163–1169. Published online 2015 May 18. doi: 10.1038/onc.2015.171

PMCID:: PMC4651851

Abstract Article PDF–553K

Select item 433458711.

Fractional exhaled nitric oxide in childhood is associated with 17q11.2-q12 and 17q12-q21 variants

Ralf JP van der Valk, Liesbeth Duijts, Nicolas J Timpson, Muhammad T Salam, Marie Standl, John A Curtin, Jon Genuneit, Marjan Kerhof, Eskil Kreiner-Møller, Alejandro Cáceres, Anna Gref, Liming L Liang, H Rob Taal, Emmanuelle Bouzigon, Florence Demenais, Rachel Nadif, Carole Ober, Emma E Thompson, Karol Estrada, Albert Hofman, André G Uitterlinden, Cornélia van Duijn, Fernando Rivadeneira, Xia Li, Sandrah P Eckel, Kiros Berhane, W James Gauderman, Raquel Granell, David M Evans, Beate St Pourcain, Wendy McArdle, John P Kemp, George Davey Smith, Carla MT Tiesler, Claudia Flexeder, Angela Simpson, Clare S Murray, Oliver Fuchs, Dirkje S Postma, Klaus Bønnelykke, Maties Torrent, Martin Andersson, Patrick Sleiman, Hakon Hakonarson, William O Cookson, Miriam F Moffatt, Lavinia Paternoster, Erik Melén, Jordi Sunyer, Hans Bisgaard, Gerard H Koppelman, Markus Ege, Adnan Custovic, Joachim Heinrich, Frank D Gilliland, Alexander J Henderson, Vincent WV Jaddoe, Johan C de Jongste, the EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium

J Allergy Clin Immunol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: J Allergy Clin Immunol. 2014 Jul; 134(1): 46–55. Published online 2013 Dec 6. doi: 10.1016/j.jaci.2013.08.053

PMCID:: PMC4334587

Abstract Article PDF–1013K

Select item 402825012.

β1,6 GlcNAc Branches-Modified PTPRT Attenuates Its Activity and Promotes Cell Migration by STAT3 Pathway

Jingjing Qi, Na Li, Kun Fan, Peng Yin, Chao Zhao, Zengxia Li, Yi Lin, Liying Wang, Xiliang Zha

PLoS One. 2014; 9(5): e98052. Published online 2014 May 20. doi: 10.1371/journal.pone.0098052

PMCID:: PMC4028250

Abstract Article PDF–1.7M

Select item 390322013.

Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer

Vivian Wai Yan Lui, Noah D. Peyser, Patrick Kwok-Shing Ng, Jozef Hritz, Yan Zeng, Yiling Lu, Hua Li, Lin Wang, Breean R. Gilbert, Ignacio J. General, Ivet Bahar, Zhenlin Ju, Zhenghe Wang, Kelsey P. Pendleton, Xiao Xiao, Yu Du, John K. Vries, Peter S. Hammerman, Levi A. Garraway, Gordon B. Mills, Daniel E. Johnson, Jennifer R. Grandis

Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3): 1114–1119. Published online 2014 Jan 6. doi: 10.1073/pnas.1319551111

PMCID:: PMC3903220

Abstract Article PDF–1.5M

Select item 356108414.

Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers

Gordan Lauc, Jennifer E. Huffman, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N. van Leeuwen, L. Renee Ruhaak, Jeanine J. Houwing-Duistermaat, P. Eline Slagboom, Marian Beekman, Anton J. M. de Craen, André M. Deelder, Qiang Zeng, Wei Wang, Nicholas D. Hastie, Ulf Gyllensten, James F. Wilson, Manfred Wuhrer, Alan F. Wright, Pauline M. Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan

PLoS Genet. 2013 Jan; 9(1): e1003225. Published online 2013 Jan 31. doi: 10.1371/journal.pgen.1003225