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Select item 112384331.

Necroptosis plays a role in TL1A-induced airway inflammation and barrier damage in asthma

Xiaofei Liu, Jintao Zhang, Dong Zhang, Yun Pan, Rong Zeng, Changjuan Xu, Shuochuan Shi, Jiawei Xu, Qian Qi, Xueli Dong, Junfei Wang, Tian Liu, Liang Dong

Respir Res. 2024; 25: 271. Published online 2024 Jul 10. doi: 10.1186/s12931-024-02900-4

PMCID:: PMC11238433

Abstract Article PDF–11M

Select item 111696202.

MicroRNA-141-regulated KLK10 and TNFSF-15 gene expression in hepatoblastoma cells as a novel mechanism in liver carcinogenesis

Ahmed M. Awad, Emad Dabous, Mai Alalem, Nedaa Alalem, Mahmoud E. Nasr, Khaled A. Elawdan, Ghada M. Nasr, Walid Said, Kareem El Khashab, Mohamed S. Basiouny, Adel A. Guirgis, Hany Khalil

Sci Rep. 2024; 14: 13492. Published online 2024 Jun 12. doi: 10.1038/s41598-024-63223-4

PMCID:: PMC11169620

Abstract Article PDF–6.5M

Select item 110103403.

TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation

Pauline Schmitt, Anais Duval, Mylène Camus, Emma Lefrançais, Stéphane Roga, Cécile Dedieu, Nathalie Ortega, Elisabeth Bellard, Emilie Mirey, Emmanuelle Mouton-Barbosa, Odile Burlet-Schiltz, Anne Gonzalez-de-Peredo, Corinne Cayrol, Jean-Philippe Girard

J Exp Med. 2024 Jun 3; 221(6): e20231236. Published online 2024 Apr 10. doi: 10.1084/jem.20231236

PMCID:: PMC11010340

Abstract Article PDF–8.6M

Select item 102907554.

Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

Zhanju Liu, Ruize Liu, Han Gao, Seulgi Jung, Xiang Gao, Ruicong Sun, Xiaoming Liu, Yongjae Kim, Ho-Su Lee, Yosuke Kawai, Masao Nagasaki, Junji Umeno, Katsushi Tokunaga, Yoshitaka Kinouchi, Atsushi Masamune, Wenzhao Shi, Chengguo Shen, Zhenglin Guo, Kai Yuan, Finn Gen, International Inflammatory Bowel Disease Genetics Consortium, Chinese Inflammatory Bowel Disease Genetics Consortium, Shu Zhu, Dalin Li, Jianjun Liu, Tian Ge, Judy Cho, Mark J. Daly, Dermot P. B. McGovern, Byong Duk Ye, Kyuyoung Song, Yoichi Kakuta, Mingsong Li, Hailiang Huang

Nat Genet. Author manuscript; available in PMC 2023 Nov 8.

Published in final edited form as: Nat Genet. 2023 May; 55(5): 796–806. Published online 2023 May 8. doi: 10.1038/s41588-023-01384-0

PMCID:: PMC10290755

Abstract Article PDF–1.9M

Select item 99150685.

Increased Serum Levels of Tumor Necrosis Factor-like Ligand 1A in Atopic Dermatitis

Teruyoshi Hisamoto, Hiraku Suga, Asako Yoshizaki-Ogawa, Shinichi Sato, Ayumi Yoshizaki

Int J Mol Sci. 2023 Feb; 24(3): 1813. Published online 2023 Jan 17. doi: 10.3390/ijms24031813

PMCID:: PMC9915068

Abstract Article PDF–1.4M

Select item 96888736.

Immune Checkpoint Inhibitor (ICI) Genes and Aging in Clear Cell Renal Cell Carcinoma (ccRCC): Clinical and Genomic Study

Abdullah Al-Danakh, Mohammed Safi, Mohammed Alradhi, Qiwei Chen, Salem Baldi, Xinqing Zhu, Deyong Yang

Cells. 2022 Nov; 11(22): 3641. Published online 2022 Nov 17. doi: 10.3390/cells11223641

PMCID:: PMC9688873

Abstract Article PDF–2.6M

Select item 96390287.

Role of TNFSF15 variants in oral cancer development and clinicopathologic characteristics

Hsueh‐Ju Lu, Chun‐Yi Chuang, Chun‐Wen Su, Mu‐Kuan Chen, Wei‐En Yang, Chia‐Ming Yeh, Chih‐Hsin Tang, Chiao‐Wen Lin, Shun‐Fa Yang

J Cell Mol Med. 2022 Nov; 26(21): 5452–5462. Published online 2022 Oct 13. doi: 10.1111/jcmm.17569

PMCID:: PMC9639028

Abstract Article PDF–2.1M

Select item 86066148.

Genome-wide association study identifies TNFSF15 associated with childhood asthma

Kyung Won Kim, Dong Yun Kim, Dankyu Yoon, Ka-Kyung Kim, Haerin Jang, Nathan Schoettler, Eun Gyul Kim, Mi Na Kim, Jung Yeon Hong, Jeom-Kyu Lee, Sangwoo Kim, Carole Ober, Heon Yung Gee, Myung Hyun Sohn

Allergy. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Allergy. 2022 Jan; 77(1): 218–229. Published online 2021 Jun 14. doi: 10.1111/all.14952

PMCID:: PMC8606614

Abstract Article PDF–1.4M

Select item 82536339.

Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis

Jia Wenxiu, Yang Mingyue, Han Fei, Luo Yuxin, Wu Mengyao, Li Chenyang, Song Jia, Zhang Hong, David Q. Shih, Stephan R. Targan, Zhang Xiaolan

Mediators Inflamm. 2021; 2021: 5927064. Published online 2021 Jun 25. doi: 10.1155/2021/5927064

PMCID:: PMC8253633

Abstract Article PDF–6.1M

Select item 810129110.

Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome

Xiaoyuan Jia, Tomohiko Yamamura, Rasheed Gbadegesin, Michelle T. McNulty, Kyuyong Song, China Nagano, Yuki Hitomi, Dongwon Lee, Yoshihiro Aiba, Seik-Soon Khor, Kazuko Ueno, Yosuke Kawai, Masao Nagasaki, Eisei Noiri, Tomoko Horinouchi, Hiroshi Kaito, Riku Hamada, Takayuki Okamoto, Koichi Kamei, Yoshitsugu Kaku, Rika Fujimaru, Ryojiro Tanaka, Yuko Shima, The Research Consortium on Genetics of Childhood Idiopathic Nephrotic Syndrome in Japan, Jiwon Baek, Hee Gyung Kang, Il-Soo Ha, Kyoung Hee Han, Eun Mi Yang, Korean Consortium of Hereditary Renal Diseases in Children, Asiri Abeyagunawardena, Brandon Lane, Megan Chryst-Stangl, Christopher Esezobor, Adaobi Solarin, Midwest Pediatric Nephrology Consortium (Genetics of nephrotic syndrome study group), Claire Dossier, Georges Deschénes, NEPHROVIR, Marina Vivarelli, Hanna Debiec, Kenji Ishikura, Masafumi Matsuo, Kandai Nozu, Pierre Ronco, Hae Il Cheong, Matthew G. Sampson, Katsushi Tokunaga, Kazumoto Iijima

Kidney Int. Author manuscript; available in PMC 2021 May 6.

Published in final edited form as: Kidney Int. 2020 Nov; 98(5): 1308–1322. Published online 2020 Jun 14. doi: 10.1016/j.kint.2020.05.029

PMCID:: PMC8101291

Abstract Article PDF–1.2M

Select item 772587911.

TL1A-DR3 plasma levels are predictive of HIV-1 disease control, and DR3 co-stimulation boosts HIV-1-specific T-cell responses

Bruna Oriol-Tordera, Alex Olvera, Clara Duran-Castells, Anuska Llano, Beatriz Mothe, Marta Massanella, Judith Dalmau, Carmela Ganoza, Jorge Sanchez, Maria Luz Calle, Bonaventura Clotet, Javier Martinez-Picado, Eugènia Negredo, Julià Blanco, Dennis Hartigan-O’Connor, Christian Brander, Marta Ruiz-Riol

J Immunol. Author manuscript; available in PMC 2021 Dec 15.

Published in final edited form as: J Immunol. 2020 Dec 15; 205(12): 3348–3357. Published online 2020 Nov 11. doi: 10.4049/jimmunol.2000933

PMCID:: PMC7725879

Abstract Article PDF–1.3M

Select item 768918412.

TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants

Rui Sun, Matija Hedl, Clara Abraham

Cell Mol Gastroenterol Hepatol. 2021; 11(1): 249–272. Published online 2020 Aug 19. doi: 10.1016/j.jcmgh.2020.08.003

PMCID:: PMC7689184

Abstract Article PDF–7.5M

Select item 757657413.

A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages, and Lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity

Nitzan Maixner, Tal Pecht, Yulia Haim, Vered Chalifa-Caspi, Nir Goldstein, Tania Tarnovscki, Idit F. Liberty, Boris Kirshtein, Rachel Golan, Omer Berner, Alon Monsonego, Nava Bashan, Matthias Blüher, Assaf Rudich

Diabetes. 2020 Nov; 69(11): 2310–2323. Published online 2020 Jul 30. doi: 10.2337/db19-1231

PMCID:: PMC7576574

Abstract Article PDF–2.3M

Select item 757628814.

TNFSF15 facilitates human umbilical cord blood haematopoietic stem cell expansion by activating Notch signal pathway

Yahui Ding, Shan Gao, Jian Shen, Tairan Bai, Ming Yang, Shiqi Xu, Yingdai Gao, Zhisong Zhang, Luyuan Li

J Cell Mol Med. 2020 Oct; 24(19): 11146–11157. Published online 2020 Sep 10. doi: 10.1111/jcmm.15626

PMCID:: PMC7576288

Abstract Article PDF–1.9M

Select item 754577915.

Polymorphism rs6478109 in the TNFSF15 gene contributes to the susceptibility to Crohn’s disease but not ulcerative colitis: a meta-analysis

Yuan Zhou, Yi Zhu, HongGang Jiang, ZhiHeng Chen, BoHao Lu, Jin Li, Xuning Shen

J Int Med Res. 2020 Oct; 48(10): 0300060520961675. Published online 2020 Oct 7. doi: 10.1177/0300060520961675

PMCID:: PMC7545779

Abstract Article PDF–1.0M

Select item 720402416.

Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

Yun-Jeong Song, In Ah. Choi, Françoise Meylan, M. Kristen Demoruelle, Taylor Farley, Arianne C. Richard, Eric Hawley, John Botson, Yoo Jin Hong, Eun Young Lee, Sabina R. Mian, Bartlett C. Hamilton, Geoffrey M. Thiele, Ted R. Mikuls, Naveen Gara, Chris D. Ward, Sarah Lamberth, Kevin D. Deane, Theo Heller, Michael M. Ward, David M. Lee, Thi-Sau Migone, William Stohl, James R. O’Dell, Jill M. Norris, V. Michael Holers, Peter Gregersen, Yeong-Wook Song, Richard M. Siegel

Arthritis Res Ther. 2020; 22: 106. Published online 2020 May 7. doi: 10.1186/s13075-020-02198-9

PMCID:: PMC7204024

Abstract Article PDF–1.6M

Select item 679223717.

Candidate single nucleotide polymorphisms of irritable bowel syndrome: a systemic review and meta-analysis

Shiwei Zhu, Ben Wang, Qiong Jia, Liping Duan

BMC Gastroenterol. 2019; 19: 165. Published online 2019 Oct 15. doi: 10.1186/s12876-019-1084-z

PMCID:: PMC6792237

Abstract Article PDF–1.6M

Select item 662633718.

Oestrogen-deficiency induces bone loss by modulating CD14⁺ monocyte and CD4⁺ T cell DR3 expression and serum TL1A levels

Fraser L. Collins, Michael D. Stone, Jane Turton, Laura R. McCabe, Eddie C. Y. Wang, Anwen S. Williams

BMC Musculoskelet Disord. 2019; 20: 326. Published online 2019 Jul 12. doi: 10.1186/s12891-019-2704-z

PMCID:: PMC6626337

Abstract Article PDF–1.1M

Select item 660803119.

The TNF family member TL1A induces IL‐22 secretion in committed human T_h17 cells via IL‐9 induction

Lisa S. Thomas, Stephan R. Targan, Masato Tsuda, Qi T. Yu, Brenda C. Salumbides, Talin Haritunians, Emebet Mengesha, Dermot P.B. McGovern, Kathrin S. Michelsen

J Leukoc Biol. 2017 Mar; 101(3): 727–737. Published online 2016 Oct 12. doi: 10.1189/jlb.3A0316-129R

PMCID:: PMC6608031

Abstract Article

Select item 658478520.

Distinct Expression Patterns of Two Tumor Necrosis Factor Superfamily Member 15 Gene Isoforms in Human Colon Cancer

Tomasz Jerzy Ślebioda, Marcin Stanisławowski, Marta Cyman, Piotr Mieczysław Wierzbicki, Dorota Żurawa-Janicka, Jarek Kobiela, Wojciech Makarewicz, Marek Guzek, Zbigniew Kmieć

Dig Dis Sci. 2019; 64(7): 1857–1867. Published online 2019 Feb 20. doi: 10.1007/s10620-019-05507-8

PMCID:: PMC6584785

Abstract Article PDF–950K

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