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Select item 112443381.

Transgenerational epigenetic self-memory of Dio3 dosage is associated with Meg3 methylation and altered growth trajectories and neonatal hormones

M. Elena Martinez, Aldona Karaczyn, Zhaofei Wu, Christian A. Bennett, Kassey L. Matoin, Heather M. Daigle, Arturo Hernandez

Epigenetics. 2024; 19(1): 2376948. Published online 2024 Jul 11. doi: 10.1080/15592294.2024.2376948

PMCID:: PMC11244338

Abstract Article PDF–7.0M

Select item 111940982.

The long non-coding RNA Meg3 mediates imprinted gene expression during stem cell differentiation

Sabina Farhadova, Amani Ghousein, François Charon, Caroline Surcis, Melisa Gomez-Velazques, Clara Roidor, Flavio Di Michele, Maud Borensztein, Albertina De Sario, Cyril Esnault, Daan Noordermeer, Benoit Moindrot, Robert Feil

Nucleic Acids Res. 2024 Jun 24; 52(11): 6183–6200. Published online 2024 Apr 13. doi: 10.1093/nar/gkae247

PMCID:: PMC11194098

Abstract Article PDF–2.5M

Select item 110889853.

Multifaceted roles of Meg3 in cellular senescence and atherosclerosis

Xiao Cheng, Mohamed Sham Shihabudeen Haider Ali, Vijaya Bhaskar Baki, Matthew Moran, Huabo Su, Xinghui Sun

Atherosclerosis. Author manuscript; available in PMC 2024 May 13.

Published in final edited form as: Atherosclerosis. 2024 May; 392: 117506. Published online 2024 Mar 8. doi: 10.1016/j.atherosclerosis.2024.117506

PMCID:: PMC11088985

Abstract Article PDF–3.0M

Select item 109608174.

Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature

Ximeijia Zhang, Hongjuan He, Haoran Yu, Xiangqi Teng, Ziwen Wang, Chenghao Li, Jiahang Li, Haopeng Yang, Jiwei Shen, Tong Wu, Fengwei Zhang, Yan Zhang, Qiong Wu

Commun Biol. 2024; 7: 363. Published online 2024 Mar 23. doi: 10.1038/s42003-024-06038-3

PMCID:: PMC10960817

Abstract Article PDF–3.1M

Select item 106435325.

The lncRNA MEG3/miRNA-21/P38MAPK axis inhibits coxsackievirus 3 replication in acute viral myocarditis

Feng He, Zhuo Liu, Miao Feng, Zonghui Xiao, Xiaoyu Yi, Jianxin Wu, Zhewei Liu, Gaoyu Wang, Le Li, Hailan Yao

Virus Res. 2024 Jan 2; 339: 199250. Published online 2023 Nov 1. doi: 10.1016/j.virusres.2023.199250

PMCID:: PMC10643532

Abstract Article PDF–4.2M

Select item 105320486.

A Lipid Nanoparticle-Based Method for the Generation of Liver-Specific Knockout Mice

Sumiyo Morita, Takuro Horii, Mika Kimura, Ryosuke Kobayashi, Hiroki Tanaka, Hidetaka Akita, Izuho Hatada

Int J Mol Sci. 2023 Sep; 24(18): 14299. Published online 2023 Sep 19. doi: 10.3390/ijms241814299

PMCID:: PMC10532048

Abstract Article PDF–1.1M

Select item 102980237.

Meg8-DMR as the Secondary Regulatory Region Regulates the Expression of MicroRNAs While It Does Not Affect Embryonic Development in Mice

Liang Zhang, Zhengbin Han, Hongjuan He, Ximeijia Zhang, Mengyan Zhang, Boran Li, Qiong Wu

Genes (Basel) 2023 Jun; 14(6): 1264. Published online 2023 Jun 14. doi: 10.3390/genes14061264

PMCID:: PMC10298023

Abstract Article PDF–4.2M

Select item 102866798.

Inhibition of MEG3 ameliorates cardiomyocyte apoptosis and autophagy by regulating the expression of miRNA-129-5p in a mouse model of heart failure

Shan Mi, Feng Huang, Mingli Jiao, Zhuang Qian, Mingming Han, Zheng Miao, Heqin Zhan

Redox Rep. 2023; 28(1): 2224607. Published online 2023 Jun 20. doi: 10.1080/13510002.2023.2224607

PMCID:: PMC10286679

Abstract Article PDF–4.1M

Select item 99776909.

The long noncoding RNA Meg3 mediates TLR4-induced inflammation in experimental obstructive nephropathy

Wai Han Yiu, Sarah W.Y. Lok, Rui Xue, Jiaoyi Chen, Kar Neng Lai, Hui Yao Lan, Sydney C.W. Tang

Clin Sci (Lond) 2023 Mar; 137(5): 317–331. Published online 2023 Mar 1. doi: 10.1042/CS20220537

PMCID:: PMC9977690

Abstract Article PDF–16M

Select item 971868310.

Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful extinction of fear

Melanie Royer, Balagopal Pai, Rohit Menon, Anna Bludau, Katharina Gryksa, Rotem Ben-Tov Perry, Igor Ulitsky, Gunter Meister, Inga D. Neumann

Mol Psychiatry. 2022; 27(10): 4064–4076. Published online 2022 Mar 25. doi: 10.1038/s41380-022-01481-2

PMCID:: PMC9718683

Abstract Article PDF–3.8M

Select item 942500511.

lncRNA MEG3 restrained the M1 polarization of microglia in acute spinal cord injury through the HuR/A20/NF‐κB axis

Heng‐Jun Zhou, Li‐Qing Wang, Ren‐Ya Zhan, Xiu‐Jue Zheng, Jie‐Sheng Zheng

Brain Pathol. 2022 Sep; 32(5): e13070. Published online 2022 Mar 25. doi: 10.1111/bpa.13070

PMCID:: PMC9425005

Abstract Article PDF–9.9M

Select item 916197712.

Long non-coding RNA MEG3 promotes tumor necrosis factor-alpha induced oxidative stress and apoptosis in interstitial cells of cajal via targeting the microRNA-21 /I-kappa-B-kinase beta axis

Jia Li, Junbo Bai, Nafeisha Tuerdi, Kaifang Liu

Bioengineered. 2022; 13(4): 8676–8688. Published online 2022 Mar 24. doi: 10.1080/21655979.2022.2054501

PMCID:: PMC9161977

Abstract Article PDF–2.4M

Select item 907235313.

Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice

Mathew Van de Pette, Andrew Dimond, António M. Galvão, Steven J. Millership, Wilson To, Chiara Prodani, Gráinne McNamara, Ludovica Bruno, Alessandro Sardini, Zoe Webster, James McGinty, Paul M. W. French, Anthony G. Uren, Juan Castillo-Fernandez, William Watkinson, Anne C. Ferguson-Smith, Matthias Merkenschlager, Rosalind M. John, Gavin Kelsey, Amanda G. Fisher

Nat Commun. 2022; 13: 2464. Published online 2022 May 5. doi: 10.1038/s41467-022-30022-2

PMCID:: PMC9072353

Abstract Article PDF–6.8M

Select item 905790014.

Glucose-6-phosphate dehydrogenase and MEG3 controls hypoxia-induced expression of serum response factor (SRF) and SRF-dependent genes in pulmonary smooth muscle cell

Atsushi Kitagawa, Christina Jacob, Sachin A. Gupte

J Smooth Muscle Res. 2022; 58: 34–49. Published online 2022 Apr 29. doi: 10.1540/jsmr.58.34

PMCID:: PMC9057900

Abstract Article PDF–3.1M

Select item 881001615.

Mechanism of M2 macrophage-derived extracellular vesicles carrying lncRNA MEG3 in inflammatory responses in ulcerative colitis

Yu-Xuan Wang, Cheng Lin, Lu-Jia Cui, Tao-Zhi Deng, Qiu-Min Li, Feng-Ying Chen, Xin-Pu Miao

Bioengineered. 2021; 12(2): 12722–12739. Published online 2021 Dec 11. doi: 10.1080/21655979.2021.2010368

PMCID:: PMC8810016

Abstract Article PDF–4.4M

Select item 831323916.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 826556617.

The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain

Maria Elena Martinez, Arturo Hernandez

Front Neurosci. 2021; 15: 703730. Published online 2021 Jun 29. doi: 10.3389/fnins.2021.703730

PMCID:: PMC8265566

Abstract Article PDF–8.3M

Select item 821245418.

Long non-coding RNA MEG3 mediates the miR-149-3p/FOXP3 axis by reducing p53 ubiquitination to exert a suppressive effect on regulatory T cell differentiation and immune escape in esophageal cancer

Qi-Rong Xu, Jian Tang, Hong-Ying Liao, Ben-Tong Yu, Xiang-Yuan He, Yu-Zhen Zheng, Sheng Liu

J Transl Med. 2021; 19: 264. Published online 2021 Jun 17. doi: 10.1186/s12967-021-02907-1

PMCID:: PMC8212454

Abstract Article PDF–1.4M

Select item 789254019.

c-MYC-induced long noncoding RNA MEG3 aggravates kidney ischemia–reperfusion injury through activating mitophagy by upregulation of RTKN to trigger the Wnt/β-catenin pathway

Dajun Liu, Ying Liu, Xiaotong Zheng, Naiquan Liu

Cell Death Dis. 2021 Feb; 12(2): 191. Published online 2021 Feb 18. doi: 10.1038/s41419-021-03466-5

PMCID:: PMC7892540

Abstract Article PDF–4.2M

Select item 784413120.

Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity

Xiao Cheng, Mohamed Sham Shihabudeen Haider Ali, Matthew Moran, Martonio Ponte Viana, Sarah L. Schlichte, Matthew C. Zimmerman, Oleh Khalimonchuk, Mark W. Feinberg, Xinghui Sun

Redox Biol. 2021 Apr; 40: 101863. Published online 2021 Jan 19. doi: 10.1016/j.redox.2021.101863

PMCID:: PMC7844131

Abstract Article PDF–2.3M

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Adjudin effect on the testis: time course
Adjudin effect on the testis: time course
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Cadmium effect on the testis: time course
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