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Select item 111481841.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 108827632.

Prognosis and biological function of SGOL1 in clear cell renal cell carcinoma: a multiomics analysis

Zezhong Yang, Yunzhong Jiang, Lu Wang, Binghe Yu, Hui Cai, Jinhai Fan, Mengzhao Zhang

BMC Med Genomics. 2024; 17: 60. Published online 2024 Feb 21. doi: 10.1186/s12920-024-01825-7

PMCID:: PMC10882763

Abstract Article PDF–14M

Select item 95403453.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 91197364.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 82562885.

A highly conserved pocket on PP2A‐B56 is required for hSgo1 binding and cohesion protection during mitosis

Yumi Ueki, Michael A Hadders, Melanie B Weisser, Isha Nasa, Paula Sotelo‐Parrilla, Lauren E Cressey, Tanmay Gupta, Emil P T Hertz, Thomas Kruse, Guillermo Montoya, A Arockia Jeyaprakash, Arminja Kettenbach, Susanne M A Lens, Jakob Nilsson

EMBO Rep. 2021 Jul 5; 22(7): e52295. Published online 2021 May 11. doi: 10.15252/embr.202052295

PMCID:: PMC8256288

Abstract Article PDF–4.0M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81001257.

Cohesin-protein Shugoshin-1 controls cardiac automaticity via HCN4 pacemaker channel

Donghai Liu, Andrew Taehun Song, Xiaoyan Qi, Patrick Piet van Vliet, Jiening Xiao, Feng Xiong, Gregor Andelfinger, Stanley Nattel

Nat Commun. 2021; 12: 2551. Published online 2021 May 5. doi: 10.1038/s41467-021-22737-5

PMCID:: PMC8100125

Abstract Article PDF–4.8M

Select item 66837318.

SET binding to Sgo1 inhibits Sgo1–cohesin interactions and promotes chromosome segregation

Qianhui Qu, Qian Zhang, Lu Yang, Yujue Chen, Hong Liu

J Cell Biol. 2019 Aug 5; 218(8): 2514–2528. Published online 2019 Jun 21. doi: 10.1083/jcb.201810096

PMCID:: PMC6683731

Abstract Article PDF–2.7M

Select item 64264559.

Mapping the genetic landscape of human cells

Max A. Horlbeck, Albert Xu, Min Wang, Neal K. Bennett, Chong Y. Park, Derek Bogdanoff, Britt Adamson, Eric D. Chow, Martin Kampmann, Tim R. Peterson, Ken Nakamura, Michael A. Fischbach, Jonathan S. Weissman, Luke A. Gilbert

Cell. Author manuscript; available in PMC 2019 Aug 9.

Published in final edited form as: Cell. 2018 Aug 9; 174(4): 953–967.e22. Published online 2018 Jul 19. doi: 10.1016/j.cell.2018.06.010

PMCID:: PMC6426455

Abstract Article PDF–3.6M

Select item 636923010.

Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics

Jessica Piché, Natacha Gosset, Lisa-Marie Legault, Alain Pacis, Andrea Oneglia, Maxime Caron, Philippe Chetaille, Luis Barreiro, Donghai Liu, Xioyan Qi, Stanley Nattel, Séverine Leclerc, Mélanie Breton-Larrivée, CoHEART Consortium, Serge McGraw, Gregor Andelfinger

Cell Mol Gastroenterol Hepatol. 2019; 7(2): 411–431. Published online 2018 Oct 24. doi: 10.1016/j.jcmgh.2018.10.011

PMCID:: PMC6369230

Abstract Article PDF–6.7M

Select item 616668211.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 615500712.

The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation

Ho-Soo Lee, Zhonghui Lin, Sunyoung Chae, Young-Suk Yoo, Byung-Gyu Kim, Youngsoo Lee, Jared L. Johnson, You-Sun Kim, Lewis C. Cantley, Chang-Woo Lee, Hongtao Yu, Hyeseong Cho

Nat Commun. 2018; 9: 3848. Published online 2018 Sep 21. doi: 10.1038/s41467-018-06377-w

PMCID:: PMC6155007

Abstract Article PDF–7.7M

Select item 613681113.

Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy

Fengchao Lang, Zhiguo Sun, Yonggang Pei, Rajnish Kumar Singh, Hem Chandra Jha, Erle S. Robertson

PLoS Pathog. 2018 Sep; 14(9): e1007253. Published online 2018 Sep 13. doi: 10.1371/journal.ppat.1007253

Correction in:: PLoS Pathog. 2019 Apr; 15(4): e1007732.

PMCID:: PMC6136811

Abstract Article PDF–3.0M

Select item 567796814.

Familial STAG2 germline mutation defines a new human cohesinopathy

Fernanda C. Soardi, Alice Machado-Silva, Natália D. Linhares, Ge Zheng, Qianhui Qu, Heloísa B. Pena, Thaís M. M. Martins, Helaine G. S. Vieira, Núbia B. Pereira, Raquel C. Melo-Minardi, Carolina C. Gomes, Ricardo S. Gomez, Dawidson A. Gomes, Douglas E. V. Pires, David B. Ascher, Hongtao Yu, Sérgio D. J. Pena

NPJ Genom Med. 2017; 2: 7. Published online 2017 Mar 20. doi: 10.1038/s41525-017-0009-4

PMCID:: PMC5677968

Abstract Article PDF–3.9M

Select item 556251215.

Phospho-H1 decorates the inter-chromatid axis and is evicted along with Shugoshin by SET during mitosis

Swathi Krishnan, Arne H Smits, Michiel Vermeulen, Danny Reinberg

Mol Cell. Author manuscript; available in PMC 2018 Aug 17.

Published in final edited form as: Mol Cell. 2017 Aug 17; 67(4): 579–593.e6. Published online 2017 Aug 3. doi: 10.1016/j.molcel.2017.07.008

PMCID:: PMC5562512

Abstract Article PDF–2.6M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 471855017.

Shugoshin-1 Balances Aurora B Kinase Activity via PP2A to Promote Chromosome Bi-orientation

Amanda Meppelink, Lilian Kabeche, Martijn J.M. Vromans, Duane A. Compton, Susanne M.A. Lens

Cell Rep. Author manuscript; available in PMC 2016 Jan 19.

Published in final edited form as: Cell Rep. 2015 Apr 28; 11(4): 508–515. Published online 2015 Apr 16. doi: 10.1016/j.celrep.2015.03.052

PMCID:: PMC4718550

Abstract Article PDF–671K

Select item 461721118.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043