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Items: 1 to 20 of 320

1.
Overexpression of wild-type HRAS drives non-alcoholic steatohepatitis to hepatocellular carcinoma in mice
Chen Ling, Su-Su Liu, Yu-Ya Wang, Gui-Tao Huo, Yan-Wei Yang, Nan Xu, Hong Wang, Yong Wu, Yu-Fa Miao, Rui Fu, Yu-Wei Zhao, Chang-Fa Fan
Zool Res. 2024 May 18; 45(3): 551–566. doi: 10.24272/j.issn.2095-8137.2024.002
PMCID:
PMC11188599
AbstractArticlePDF–27M
2.
Lack of effect of human c‐Ha‐ras proto‐oncogene overexpression on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats
Naomi Hokaiwado, Makoto Asamoto, Young‐Man Cho, Hiroyuki Tsuda, Tomoyuki Shirai
Cancer Sci. 2003 Dec; 94(12): 1042–1045. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01398.x
PMCID:
PMC11160280
AbstractArticlePDF–1.0M
3.
Predictive advantage of a cell type classification for pulmonary adenocarcinoma coupled with data for p53, K‐ras and EGFR alterations
Akira Okada, Takuo Shimmyo, Takehisa Hashimoto, Yasuhito Kobayashi, Yohei Miyagi, Yuichi Ishikawa, Ken Nakagawa, Junichi Hayashi, Eiju Tsuchiya
Cancer Sci. 2010 Jul; 101(7): 1745–1753. Published online 2010 Apr 7. doi: 10.1111/j.1349-7006.2010.01585.x
PMCID:
PMC11159221
AbstractArticlePDF–366K
4.
Crystal Structure of an i-Motif from the HRAS Oncogene Promoter
Kevin S. Li, Deondre Jordan, Linda Y. Lin, Sawyer E. McCarthy, John S. Schneekloth, Jr., Liliya A. Yatsunyk
Angew Chem Int Ed Engl. Author manuscript; available in PMC 2024 Jun 26.
Published in final edited form as: Angew Chem Int Ed Engl. 2023 Jun 26; 62(26): e202301666. Published online 2023 Apr 25. doi: 10.1002/anie.202301666
PMCID:
PMC10330059
AbstractArticlePDF–1.3M
5.
A Subset of Salivary Intercalated Duct Lesions Harbors Recurrent CTNNB1 and HRAS Mutations: A Molecular Link to Basal Cell Adenoma and Epithelial-Myoepithelial Carcinoma?
Anne C. McLean, Lisa M. Rooper, Jeffrey Gagan, Lester D. R. Thompson, Justin A. Bishop
Head Neck Pathol. 2023 Jun; 17(2): 393–400. Published online 2022 Dec 8. doi: 10.1007/s12105-022-01513-x
PMCID:
PMC10293506
AbstractArticlePDF–2.0M
6.
Cytosolic EpCAM cooperates with H-Ras to regulate epithelial to mesenchymal transition through ZEB1
Fatma A. Omar, Taylor C. Brown, William E. Gillanders, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal
PLoS One. 2023; 18(5): e0285707. Published online 2023 May 16. doi: 10.1371/journal.pone.0285707
PMCID:
PMC10187930
AbstractArticlePDF–4.1M
7.
Mutated HRAS activates YAP1-AXL signaling to drive metastasis of head and neck cancer
Sankar Jagadeeshan, Manu Prasad, Mai Badarni, Talal Ben Lulu, Vijayasteltar Belsamma Liju, Sooraj Mathukkada, Claire Saunders, Avital Beeri Shnerb, Jonathan Zorea, Ksenia M Yegodayev, Monica Wainer, Liza Vtorov, Irit Allon, Ofir Cohen, Gro Gausdal, Dinorah Friedmann-Morvinski, Sok Ching Cheong, Alan L Ho, Ari J Rosenberg, Linda Kessler, Francis Burrows, Dexin Kong, Jennifer R Grandis, J Silvio Gutkind, Moshe Elkabets
Cancer Res. Author manuscript; available in PMC 2023 Oct 4.
Published in final edited form as: Cancer Res. 2023 Apr 4; 83(7): 1031–1047. doi: 10.1158/0008-5472.CAN-22-2586
PMCID:
PMC10073343
AbstractArticlePDF–2.6M
8.
HRAS overexpression predicts response to Lenvatinib treatment in gastroenteropancreatic neuroendocrine tumors
Chiara Liverani, Chiara Spadazzi, Toni Ibrahim, Federica Pieri, Flavia Foca, Chiara Calabrese, Alessandro De Vita, Giacomo Miserocchi, Claudia Cocchi, Silvia Vanni, Giorgio Ercolani, Davide Cavaliere, Nicoletta Ranallo, Elisa Chiadini, Giovanna Prisinzano, Stefano Severi, Maddalena Sansovini, Giovanni Martinelli, Alberto Bongiovanni, Laura Mercatali
Front Endocrinol (Lausanne) 2022; 13: 1045038. Published online 2023 Jan 20. doi: 10.3389/fendo.2022.1045038
PMCID:
PMC9895371
AbstractArticlePDF–4.0M
9.
SPOP inhibits BRAF-dependent tumorigenesis through promoting non-degradative ubiquitination of BRAF
Kai Feng, Qing Shi, Dongyue Jiao, Yingji Chen, Wanqi Yang, Ke Su, Yalan Wang, Yan Huang, Pingzhao Zhang, Yao Li, Chenji Wang
Cell Biosci. 2022; 12: 211. Published online 2022 Dec 30. doi: 10.1186/s13578-022-00950-z
PMCID:
PMC9805134
AbstractArticlePDF–9.4M
10.
A novel HRAS c.466C>T p.(Phe156Leu) variant in two patients with attenuated features of Costello syndrome
Suzanna Lindsey-Temple, Matt Edwards, Verena Rickassel, Theresa Nauth, Georg Rosenberger
Eur J Hum Genet. 2022 Sep; 30(9): 1088–1093. Published online 2022 Jun 29. doi: 10.1038/s41431-022-01139-1
PMCID:
PMC9437031
AbstractArticlePDF–1.1M
11.
HRAS Q61L Mutation as a Possible Target for Non-Small Cell Lung Cancer: Case Series and Review of Literature
Laurent Mathiot, Guillaume Herbreteau, Siméon Robin, Charlotte Fenat, Jaafar Bennouna, Christophe Blanquart, Marc Denis, Elvire Pons-Tostivint
Curr Oncol. 2022 May; 29(5): 3748–3758. Published online 2022 May 20. doi: 10.3390/curroncol29050300
PMCID:
PMC9139372
AbstractArticlePDF–976K
12.
A protein interaction landscape of breast cancer
Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan
Science. Author manuscript; available in PMC 2022 Apr 26.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066
PMCID:
PMC9040556
AbstractArticlePDF–2.2M
13.
HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models
Laetitia Dard, Christophe Hubert, Pauline Esteves, Wendy Blanchard, Ghina Bou About, Lyla Baldasseroni, Elodie Dumon, Chloe Angelini, Mégane Delourme, Véronique Guyonnet-Dupérat, Stéphane Claverol, Laura Fontenille, Karima Kissa, Pierre-Emmanuel Séguéla, Jean-Benoît Thambo, Lévy Nicolas, Yann Herault, Nadège Bellance, Nivea Dias Amoedo, Frédérique Magdinier, Tania Sorg, Didier Lacombe, Rodrigue Rossignol
J Clin Invest. 2022 Apr 15; 132(8): e131053. Published online 2022 Apr 15. doi: 10.1172/JCI131053
PMCID:
PMC9012293
AbstractArticlePDF–14M
14.
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity
Danielle L. Swaney, Dana J. Ramms, Zhiyong Wang, Jisoo Park, Yusuke Goto, Margaret Soucheray, Neil Bhola, Kyumin Kim, Fan Zheng, Yan Zeng, Michael McGregor, Kari A. Herrington, Rachel O’Keefe, Nan Jin, Nathan K. VanLandingham, Helene Foussard, John Von Dollen, Mehdi Bouhaddou, David Jimenez-Morales, Kirsten Obernier, Jason F. Kreisberg, Minkyu Kim, Daniel E. Johnson, Natalia Jura, Jennifer R. Grandis, J. Silvio Gutkind, Trey Ideker, Nevan J. Krogan
Science. Author manuscript; available in PMC 2022 Apr 13.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf2911. Published online 2021 Oct 1. doi: 10.1126/science.abf2911
PMCID:
PMC9005332
AbstractArticlePDF–2.0M
15.
Targeted Long-Read Sequencing Decodes the Transcriptional Atlas of the Founding RAS Gene Family Members
Panagiotis G. Adamopoulos, Panagiotis Tsiakanikas, Michaela A. Boti, Andreas Scorilas
Int J Mol Sci. 2021 Dec; 22(24): 13298. Published online 2021 Dec 10. doi: 10.3390/ijms222413298
PMCID:
PMC8709048
AbstractArticlePDF–2.2M
16.
Higher RET Gene Expression Levels Do Not Represent anAlternative RET Activation Mechanism in Medullary Thyroid Carcinoma
Chiara Mulè, Raffaele Ciampi, Teresa Ramone, Alessandro Prete, Antonio Matrone, Virginia Cappagli, Liborio Torregrossa, Fulvio Basolo, Rossella Elisei, Cristina Romei
Biomolecules. 2021 Oct; 11(10): 1542. Published online 2021 Oct 19. doi: 10.3390/biom11101542
PMCID:
PMC8533768
AbstractArticlePDF–1.4M
17.
HRAS is a therapeutic target in malignant chemo-resistant adenomyoepithelioma of the breast
Ivan Bièche, Florence Coussy, Rania El-Botty, Sophie Vacher, Sophie Château-Joubert, Ahmed Dahmani, Elodie Montaudon, Cécile Reyes, David Gentien, Fabien Reyal, Francesco Ricci, André Nicolas, Caterina Marchio, Anne Vincent-Salomon, Marick Laé, Elisabetta Marangoni
J Hematol Oncol. 2021; 14: 143. Published online 2021 Sep 8. doi: 10.1186/s13045-021-01158-3
PMCID:
PMC8424935
AbstractArticlePDF–1.0M
18.
Expression of oncogenic HRAS in human Rh28 and RMS-YM rhabdomyosarcoma cells leads to oncogene-induced senescence
Jenny J. Li, Alexander R. Kovach, Margaret DeMonia, Katherine K. Slemmons, Kristianne M. Oristian, Candy Chen, Corinne M. Linardic
Sci Rep. 2021; 11: 16505. Published online 2021 Aug 13. doi: 10.1038/s41598-021-95355-2
PMCID:
PMC8363632
AbstractArticlePDF–2.0M
19.
Crystal Structure Reveals the Full Ras–Raf Interface and Advances Mechanistic Understanding of Raf Activation
Trinity Cookis, Carla Mattos
Biomolecules. 2021 Jul; 11(7): 996. Published online 2021 Jul 7. doi: 10.3390/biom11070996
PMCID:
PMC8301913
AbstractArticlePDF–5.6M
20.
Tipifarnib in Recurrent, Metastatic HRAS-Mutant Salivary Gland Cancer
Glenn J. Hanna, Jeffrey P. Guenette, Nicole G. Chau, Cyrus M. Sayehli, Christian Wilhelm, Robert Metcalf, Deborah J. Wong, Marcia Brose, Mohammad Razaq, Elisabeth Pérez-Ruiz, Ezra E. W. Cohen, Rahul Aggarwal, Catherine Scholz, Antonio Gualberto, Alan L. Ho
Cancer. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: Cancer. 2020 Sep 1; 126(17): 3972–3981. Published online 2020 Jun 18. doi: 10.1002/cncr.33036
PMCID:
PMC8266417
AbstractArticlePDF–1.0M

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