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Select item 109168731.

Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif

Jason Ecard, Yen-Ling Lian, Séverine Divoux, Zelia Gouveia, Emmanuelle Vigne, Franck Perez, Gaelle Boncompain

Mol Biol Cell. 2024 Mar 1; 35(3): ar42. Published online 2024 Feb 5. doi: 10.1091/mbc.E23-06-0251

PMCID:: PMC10916873

Abstract Article PDF–1.9M

Select item 109013592.

Enterovirus A71 does not meet the uncoating receptor SCARB2 at the cell surface

Yorihiro Nishimura, Kei Sato, Yoshio Koyanagi, Takaji Wakita, Masamichi Muramatsu, Hiroyuki Shimizu, Jeffrey M. Bergelson, Minetaro Arita

PLoS Pathog. 2024 Feb; 20(2): e1012022. Published online 2024 Feb 15. doi: 10.1371/journal.ppat.1012022

PMCID:: PMC10901359

Abstract Article PDF–3.0M

Select item 105170163.

SCARB2 drives hepatocellular carcinoma tumor initiating cells via enhanced MYC transcriptional activity

Feng Wang, Yang Gao, Situ Xue, Luyao Zhao, Huimin Jiang, Tingting Zhang, Yunxuan Li, Chenxi Zhao, Fan Wu, Tana Siqin, Ying Liu, Jie Wu, Yechao Yan, Jian Yuan, Jian-dong Jiang, Ke Li

Nat Commun. 2023; 14: 5917. Published online 2023 Sep 22. doi: 10.1038/s41467-023-41593-z

PMCID:: PMC10517016

Abstract Article PDF–9.4M

Select item 104948564.

The effects of SCARB2 and SELPLG gene polymorphisms on EV71 infection in hand, foot, and mouth disease

Fengyuan Duan, Zengqing Du, Yang Wang, Lan Luo, Lijiang Du, Hong Jiang, Yantuanjin Ma, Yuling Yang

Biomol Biomed. 2023 Oct 1; 23(5): 815–824. Published online 2023 Oct 1. doi: 10.17305/bb.2023.8948

PMCID:: PMC10494856

Abstract Article PDF–2.1M

Select item 102504535.

LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma

Yuantong Liu, Shujin Li, Shuo Wang, Qichao Yang, Zhizhong Wu, Mengjie Zhang, Lei Chen, Zhijun Sun

Int J Oral Sci. 2023; 15: 24. Published online 2023 Jun 8. doi: 10.1038/s41368-023-00229-0

PMCID:: PMC10250453

Abstract Article PDF–14M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101448297.

Human SCARB2 Acts as a Cellular Associator for Helping Coxsackieviruses A10 Infection

Shu-Ling Yu, Nai-Hsiang Chung, Yu-Ching Lin, Yi-An Liao, Ying-Chin Chen, Yen-Hung Chow

Viruses. 2023 Apr; 15(4): 932. Published online 2023 Apr 8. doi: 10.3390/v15040932

PMCID:: PMC10144829

Abstract Article PDF–3.0M

Select item 92316238.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 909310710.

SLC35B2 Acts in a Dual Role in the Host Sulfation Required for EV71 Infection

Dong Guo, Xinghai Yu, Dan Wang, Zhifei Li, Yu Zhou, Guodong Xu, Bing Yuan, Yali Qin, Mingzhou Chen

J Virol. 2022 May; 96(9): e02042-21. Published online 2022 Apr 14. doi: 10.1128/jvi.02042-21

PMCID:: PMC9093107

Abstract Article PDF–6.5M

Select item 889702211.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 889438012.

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing

Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl

Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2

PMCID:: PMC8894380

Abstract Article PDF–5.6M

Select item 863966813.

TRIP12 Ubiquitination of Glucocerebrosidase Contributes to Neurodegeneration in Parkinson’s Disease

Bo Am Seo, Donghoon Kim, Heehong Hwang, Min Seong Kim, Shi-Xun Ma, Seung-Hwan Kwon, Sin Ho Kweon, Hu Wang, Je Min Yoo, Seulah Choi, Sang Ho Kwon, Sung-Ung Kang, Tae-In Kam, Kwangsoo Kim, Senthilkumar S Karuppagounder, Bong Gu Kang, Saebom Lee, Hyejin Park, Sangjune Kim, Wei Yan, Yong-Shi Li, Sheng-Han Kuo, Javier Redding-Ochoa, Olga Pletnikova, Juan C. Troncoso, Gabsang Lee, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Han Seok Ko

Neuron. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Neuron. 2021 Dec 1; 109(23): 3758–3774.e11. Published online 2021 Oct 12. doi: 10.1016/j.neuron.2021.09.031

PMCID:: PMC8639668

Abstract Article PDF–2.6M

Select item 855290714.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 851347015.

Enterovirus A71 Induces Neurological Diseases and Dynamic Variants in Oral Infection of Human SCARB2-Transgenic Weaned Mice

Jing-Yi Lin, Kuo-Feng Weng, Chih-Kuang Chang, Yu-Nong Gong, Guo-Jen Huang, Hui-Lan Lee, Yen-Cheng Chen, Chien-Chih Huang, Jia-Ying Lu, Peng-Nien Huang, Huan-Jung Chiang, Che-Min Chen, Shin-Ru Shih

J Virol. 2021 Nov; 95(21): e00897-21. Prepublished online 2021 Aug 11. Published online 2021 Oct 13. doi: 10.1128/JVI.00897-21

PMCID:: PMC8513470

Abstract Article PDF–5.8M

Select item 844517216.

Class B Scavenger Receptors BI and BII Protect against LPS-Induced Acute Lung Injury in Mice by Mediating LPS

Irina N. Baranova, Alexander V. Bocharov, Tatyana G. Vishnyakova, Zhigang Chen, Anna A. Birukova, Yunbo Ke, Xuzhen Hu, Peter S. T. Yuen, Robert A. Star, Konstantin G. Birukov, Amy P. Patterson, Thomas L. Eggerman

Infect Immun. 2021 Oct; 89(10): e00301-21. Prepublished online 2021 Jun 7. Published online 2021 Sep 16. doi: 10.1128/IAI.00301-21

Correction in:: Infect Immun. 2022 Oct; 90(10): e00404-22.

PMCID:: PMC8445172

Abstract Article PDF–1.7M

Select item 824414217.

Relationship between polymorphism of receptor SCARB2 gene and clinical severity of enterovirus-71 associated hand-foot-mouth disease

Xia Wang, Hong Liu, Ying Li, Rui Su, Yamin Liu, Kunyan Qiao

Virol J. 2021; 18: 132. Published online 2021 Jun 30. doi: 10.1186/s12985-021-01605-0

PMCID:: PMC8244142

Abstract Article PDF–1009K

Select item 816503018.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 795946319.

GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice

Martijn J. C. van der Lienden, Jan Aten, André R. A. Marques, Ingeborg S. E. Waas, Per W. B. Larsen, Nike Claessen, Nicole N. van der Wel, Roelof Ottenhoff, Marco van Eijk, Johannes M. F. G. Aerts

Int J Mol Sci. 2021 Mar; 22(5): 2532. Published online 2021 Mar 3. doi: 10.3390/ijms22052532

PMCID:: PMC7959463

Abstract Article PDF–8.7M

Select item 781650520.

Fibroblasts from idiopathic Parkinson’s disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2

Ria Thomas, Elizabeth B. Moloney, Zachary K. Macbain, Penelope J. Hallett, Ole Isacson

Mol Brain. 2021; 14: 16. Published online 2021 Jan 19. doi: 10.1186/s13041-020-00712-3

PMCID:: PMC7816505

Abstract Article PDF–991K

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