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Select item 93870541.

Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases

Sherona R. Sirkisoon, Grace L. Wong, Noah R. Aguayo, Daniel L. Doheny, Dongqin Zhu, Angelina T. Regua, Austin Arrigo, Sara G. Manore, Calvin Wagner, Alexandra Thomas, Ravi Singh, Fei Xing, Guangxu Jin, Kounosuke Watabe, Hui-Wen Lo

Cancer Lett. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: Cancer Lett. 2022 Aug 1; 540: 215726. Published online 2022 May 16. doi: 10.1016/j.canlet.2022.215726

PMCID:: PMC9387054

Abstract Article PDF–1.5M

Select item 91176812.

Ciliary neurotrophic factor is increased in the plasma of patients with obesity and its levels correlate with diabetes and inflammation indices

Jessica Perugini, Eleonora Di Mercurio, Angelica Giuliani, Jacopo Sabbatinelli, Anna Rita Bonfigli, Elena Tortato, Ilenia Severi, Saverio Cinti, Fabiola Olivieri, Carel W. le Roux, Rosaria Gesuita, Antonio Giordano

Sci Rep. 2022; 12: 8331. Published online 2022 May 18. doi: 10.1038/s41598-022-11942-x

PMCID:: PMC9117681

Abstract Article PDF–2.7M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79275704.

Ciliary neurotrophic factor: a survival and differentiation inducer in human retinal progenitors

Kamla Dutt, Yang Cao, Ifeoma Ezeonu

In Vitro Cell Dev Biol Anim. Author manuscript; available in PMC 2021 Mar 3.

Published in final edited form as: In Vitro Cell Dev Biol Anim. 2010 Jul; 46(7): 635–646. Published online 2010 Apr 29. doi: 10.1007/s11626-010-9319-x

PMCID:: PMC7927570

Abstract Article PDF–1.8M

Select item 75862525.

Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRɑ) signal through MAPK/ERK pathway in human prostate tissues: A morphological and biomolecular study

Sonia Fantone, Giovanni Tossetta, Rodolfo Montironi, Martina Senzacqua, Daniela Marzioni, Roberta Mazzucchelli

Eur J Histochem. 2020 Oct 19; 64(4): 3147. Published online 2020 Oct 19. doi: 10.4081/ejh.2020.3147

PMCID:: PMC7586252

Abstract Article PDF–568K

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 66747217.

Regulation of Rod Phototransduction Machinery by Ciliary Neurotrophic Factor

Rong Wen, Ying Song, Sten Kjellstrom, Atsuhiro Tanikawa, Yun Liu, Yiwen Li, Lian Zhao, Ronald A. Bush, Alan M. Laties, Paul A. Sieving

J Neurosci. 2006 Dec 27; 26(52): 13523–13530. doi: 10.1523/JNEUROSCI.4021-06.2006

PMCID:: PMC6674721

Abstract Article PDF–504K

Select item 66703218.

CNTF: A Putative Link between Dopamine D₂ Receptors and Neurogenesis

Mayra Mori, Julius J. Jefferson, Michele Hummel, David S. Garbe

J Neurosci. 2008 Jun 4; 28(23): 5867–5869. doi: 10.1523/JNEUROSCI.1782-08.2008

PMCID:: PMC6670321

Article PDF–102K

Select item 65683559.

Apolipoprotein E Binds to and Potentiates the Biological Activity of Ciliary Neurotrophic Factor

Catherine R. Gutman, Warren J. Strittmatter, Karl H. Weisgraber, William D. Matthew

J Neurosci. 1997 Aug 15; 17(16): 6114–6121. doi: 10.1523/JNEUROSCI.17-16-06114.1997

PMCID:: PMC6568355

Abstract Article PDF–491K

Select item 621328310.

Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress

Alán Alpár, Péter Zahola, János Hanics, Zsófia Hevesi, Solomiia Korchynska, Marco Benevento, Christian Pifl, Gergely Zachar, Jessica Perugini, Ilenia Severi, Patrick Leitgeb, Joanne Bakker, Andras G Miklosi, Evgenii Tretiakov, Erik Keimpema, Gloria Arque, Ramon O Tasan, Günther Sperk, Katarzyna Malenczyk, Zoltán Máté, Ferenc Erdélyi, Gábor Szabó, Gert Lubec, Miklós Palkovits, Antonio Giordano, Tomas GM Hökfelt, Roman A Romanov, Tamas L Horvath, Tibor Harkany

EMBO J. 2018 Nov 2; 37(21): e100087. Published online 2018 Sep 12. doi: 10.15252/embj.2018100087

PMCID:: PMC6213283

Abstract Article PDF–3.0M

Select item 566346511.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

Select item 553928412.

Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas

Kun Fan, Xiaowen Wang, Jingwen Zhang, Romela Irene Ramos, Haibo Zhang, Chunjie Li, Dan Ye, Jiansheng Kang, Diego M. Marzese, Dave S. B. Hoon, Wei Hua

Sci Rep. 2017; 7: 7079. Published online 2017 Aug 1. doi: 10.1038/s41598-017-07124-9

PMCID:: PMC5539284

Abstract Article PDF–1.2M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 464025614.

The neuroprotective agent CNTF decreases neuronal metabolites in the rat striatum: an in vivo multimodal magnetic resonance imaging study

Maria-Angeles Carrillo-de Sauvage, Julien Flament, Yann Bramoulle, Lucile Ben Haim, Martine Guillermier, Aurélie Berniard, Gwennaëlle Aurégan, Diane Houitte, Emmanuel Brouillet, Gilles Bonvento, Philippe Hantraye, Julien Valette, Carole Escartin

J Cereb Blood Flow Metab. 2015 Jun; 35(6): 917–921. Published online 2015 Apr 1. doi: 10.1038/jcbfm.2015.48

PMCID:: PMC4640256

Abstract Article PDF–332K

Select item 426658815.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 414024816.

The Amino Acid Exchange R28E in Ciliary Neurotrophic Factor (CNTF) Abrogates Interleukin-6 Receptor-dependent but Retains CNTF Receptor-dependent Signaling via Glycoprotein 130 (gp130)/Leukemia Inhibitory Factor Receptor (LIFR)

Eva-Maria Wagener, Matthias Aurich, Samadhi Aparicio-Siegmund, Doreen M. Floss, Christoph Garbers, Kati Breusing, Björn Rabe, Ralf Schwanbeck, Joachim Grötzinger, Stefan Rose-John, Jürgen Scheller

J Biol Chem. 2014 Jun 27; 289(26): 18442–18450. Published online 2014 May 6. doi: 10.1074/jbc.M114.568857

PMCID:: PMC4140248

Abstract Article PDF–1.5M

Select item 386782117.

Crosstalk between KLF4 and STAT3 regulates axon regeneration

Song Qin, Yuhua Zou, Chun-Li Zhang

Nat Commun. Author manuscript; available in PMC 2013 Dec 19.

Published in final edited form as: Nat Commun. 2013; 4: 2633. doi: 10.1038/ncomms3633

PMCID:: PMC3867821

Abstract Article PDF–1.6M

Select item 383970718.

CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Müller glial cells

Kun Do Rhee, Steven Nusinowitz, Kevin Chao, Fei Yu, Dean Bok, Xian-Jie Yang

Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47): E4520–E4529. Published online 2013 Nov 4. doi: 10.1073/pnas.1303604110

PMCID:: PMC3839707

Abstract Article PDF–3.3M

Select item 368999419.

Up-regulation of Ciliary Neurotrophic Factor in Astrocytes by Aspirin: IMPLICATIONS FOR REMYELINATION IN MULTIPLE SCLEROSIS

Khushbu K. Modi, Michael Sendtner, Kalipada Pahan

J Biol Chem. 2013 Jun 21; 288(25): 18533–18545. Published online 2013 May 7. doi: 10.1074/jbc.M112.447268

PMCID:: PMC3689994

Abstract Article PDF–2.6M

Select item 349180320.

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho

Nature. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582

PMCID:: PMC3491803

Abstract Article PDF–706K

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