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Select item 110117971.

PARP14 Contributes to the Development of the Tumor-Associated Macrophage Phenotype

Isotta Sturniolo, Csongor Váróczy, Zsolt Regdon, Anett Mázló, Szabolcs Muzsai, Attila Bácsi, Giorgia Intili, Csaba Hegedűs, Mark R. Boothby, Jacob Holechek, Dana Ferraris, Herwig Schüler, László Virág

Int J Mol Sci. 2024 Apr; 25(7): 3601. Published online 2024 Mar 22. doi: 10.3390/ijms25073601

PMCID:: PMC11011797

Abstract Article PDF–6.5M

Select item 106381452.

Exploration of glycosyltransferases mutation status in cervical cancer reveals PARP14 as a potential prognostic marker

Hui Wang, Shen Luo, Xin Wu, Yuanyuan Ruan, Ling Qiu, Hao Feng, Shurong Zhu, Yanan You, Ming Li, Wenting Yang, Yanding Zhao, Xiang Tao, Hua Jiang

Glycoconj J. 2023; 40(5): 513–522. Published online 2023 Aug 31. doi: 10.1007/s10719-023-10134-7

PMCID:: PMC10638145

Abstract Article PDF–4.8M

Select item 105658763.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101516155.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 100058986.

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA

Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay

J Cell Biol. 2023 Apr 3; 222(4): e202201027. Published online 2023 Feb 28. doi: 10.1083/jcb.202201027

PMCID:: PMC10005898

Abstract Article PDF–6.7M

Select item 94771637.

NMR study of human macroPARPs domains: ¹H, ¹⁵N and ¹³C resonance assignment of hPARP14 macro domain 2 in the free and the ADPr bound state

Nikolaos K. Fourkiotis, Periklis Charalampous, Aikaterini C. Tsika, Konstantina P. Kravvariti, Christos Sideras-Bisdekis, Angelo Gallo, Georgios A. Spyroulias

Biomol NMR Assign. 2022; 16(2): 399–406. Published online 2022 Sep 15. doi: 10.1007/s12104-022-10110-6

PMCID:: PMC9477163

Abstract Article PDF–4.2M

Select item 83844558.

PARP14 regulates cyclin D1 expression to promote cell cycle progression

Michael J. O’Connor, Tanay Thakar, Claudia M. Nicolae, George-Lucian Moldovan

Oncogene. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Oncogene. 2021 Jul; 40(30): 4872–4883. Published online 2021 Jun 22. doi: 10.1038/s41388-021-01881-8

PMCID:: PMC8384455

Abstract Article PDF–2.3M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 801772010.

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118

PMCID:: PMC8017720

Abstract Article PDF–1.9M

Select item 796299411.

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy

Yanke Chen, Ting Jiang, Hongyi Zhang, Xingchun Gou, Cong Han, Jianhui Wang, Ann T. Chen, Jun Ma, Jun Liu, Zeming Chen, Xintao Jing, Hong Lei, Zhenzhen Wang, Youmei Bao, Mehdi Baqri, Yong Zhu, Ranjit S. Bindra, James E. Hansen, Jun Dou, Chen Huang, Jiangbing Zhou

Nat Cell Biol. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Nat Cell Biol. 2020 Oct; 22(10): 1276–1285. Published online 2020 Oct 1. doi: 10.1038/s41556-020-00586-6

PMCID:: PMC7962994

Abstract Article PDF–5.5M

Select item 781877112.

The potential association between PARP14 and the SARS-CoV-2 infection (COVID-19)

Amanda L Tauber, Stephanie S Schweiker, Stephan M Levonis

Future Med Chem. 2021 Jan : 10.4155/fmc-2020-0226. Published online 2021 Jan 20. doi: 10.4155/fmc-2020-0226

PMCID:: PMC7818771

Abstract Article PDF–261K

Select item 736720013.

Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR

Ashna Dhoonmoon, Emily M Schleicher, Kristen E Clements, Claudia M Nicolae, George-Lucian Moldovan

Nucleic Acids Res. 2020 Jul 27; 48(13): 7252–7264. Published online 2020 Jun 15. doi: 10.1093/nar/gkaa508

PMCID:: PMC7367200

Abstract Article PDF–5.9M

Select item 659455114.

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin

Cell Rep. Author manuscript; available in PMC 2019 Jun 26.

Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060

PMCID:: PMC6594551

Abstract Article PDF–1.4M

Select item 645686815.

A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP-1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation

Hideyuki Higashi, Takashi Maejima, Lang Ho Lee, Yukiyoshi Yamazaki, Michael O. Hottiger, Sasha A. Singh, Masanori Aikawa

J Proteome Res. 2019 Apr 5; 18(4): 1607–1622. Published online 2019 Mar 8. doi: 10.1021/acs.jproteome.8b00895

PMCID:: PMC6456868

Abstract Article PDF–5.6M

Select item 638658816.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Abstract Article PDF–1.7M

Select item 584953417.

Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS

Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al-Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Trevino, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda

Cancer Cell. Author manuscript; available in PMC 2019 Mar 12.

Published in final edited form as: Cancer Cell. 2018 Mar 12; 33(3): 386–400.e5. Published online 2018 Feb 22. doi: 10.1016/j.ccell.2018.01.012

PMCID:: PMC5849534

Abstract Article PDF–1.1M

Select item 582692618.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 509804219.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Giorgio Oliviero, Gerard L. Brien, Ariane Waston, Gundula Streubel, Emilia Jerman, Darrell Andrews, Benjamin Doyle, Nayla Munawar, Kieran Wynne, John Crean, Adrian P. Bracken, Gerard Cagney

Mol Cell Proteomics. 2016 Nov; 15(11): 3450–3460. Published online 2016 Sep 15. doi: 10.1074/mcp.M116.062240

PMCID:: PMC5098042

Abstract Article PDF–1.9M

Select item 509553220.

PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation

Hiroshi Iwata, Claudia Goettsch, Amitabh Sharma, Piero Ricchiuto, Wilson Wen Bin Goh, Arda Halu, Iwao Yamada, Hideo Yoshida, Takuya Hara, Mei Wei, Noriyuki Inoue, Daiju Fukuda, Alexander Mojcher, Peter C. Mattson, Albert-László Barabási, Mark Boothby, Elena Aikawa, Sasha A. Singh, Masanori Aikawa

Nat Commun. 2016; 7: 12849. Published online 2016 Oct 31. doi: 10.1038/ncomms12849

PMCID:: PMC5095532

Abstract Article PDF–4.6M

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