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Select item 111782131.

Interplay between Pitx2 and Pax7 temporally governs specification of extraocular muscle stem cells

Mao Kuriki, Amaury Korb, Glenda Comai, Shahragim Tajbakhsh

PLoS Genet. 2024 Jun; 20(6): e1010935. Published online 2024 Jun 14. doi: 10.1371/journal.pgen.1010935

PMCID:: PMC11178213

Abstract Article PDF–6.0M

Select item 111419332.

Intergenic sequences harboring potential enhancer elements contribute to Axenfeld-Rieger syndrome by regulating PITX2

Yizheng Jiang, Yu Peng, Qi Tian, Zhe Cheng, Bei Feng, Junping Hu, Lu Xia, Hui Guo, Kun Xia, Liang Zhou, Zhengmao Hu

JCI Insight. 2024 May 8; 9(9): e177032. Published online 2024 Apr 9. doi: 10.1172/jci.insight.177032

PMCID:: PMC11141933

Abstract Article PDF–2.4M

Select item 109811583.

Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity

Seungwoon Seo, Seong Keun Sonn, Hyae Yon Kweon, Jing Jin, Tsutomu Kume, Je Yeong Ko, Jong Hoon Park, Goo Taeg Oh

Invest Ophthalmol Vis Sci. 2024 Mar; 65(3): 30. Published online 2024 Mar 22. doi: 10.1167/iovs.65.3.30

PMCID:: PMC10981158

Abstract Article PDF–20M

Select item 109262044.

Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

Mary E. Mohr, Shuang Li, Allison M. Trouten, Rebecca A. Stairley, Patrick L. Roddy, Chun Liu, Min Zhang, Henry M. Sucov, Ge Tao

iScience. 2024 Mar 15; 27(3): 109219. Published online 2024 Feb 15. doi: 10.1016/j.isci.2024.109219

PMCID:: PMC10926204

Abstract Article PDF–13M

Select item 109176605.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108842406.

Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects

Sabrina Quilez, Emilie Dumontier, Christopher Baim, Joseph Kam, Jean-François Cloutier

Front Cell Dev Biol. 2024; 12: 1256465. Published online 2024 Feb 9. doi: 10.3389/fcell.2024.1256465

PMCID:: PMC10884240

Abstract Article PDF–6.8M

Select item 108534537.

Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi

Hong-Nhung Tran, Quy-Hoai Nguyen, Yongsu Jeong

Front Cell Dev Biol. 2024; 12: 1336308. Published online 2024 Jan 26. doi: 10.3389/fcell.2024.1336308

PMCID:: PMC10853453

Abstract Article PDF–8.4M

Select item 106562348.

Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development

Dan Su, Steve Eliason, Zhao Sun, Fan Shao, Brad A. Amendt

J Biol Chem. 2023 Nov; 299(11): 105324. Published online 2023 Oct 6. doi: 10.1016/j.jbc.2023.105324

PMCID:: PMC10656234

Abstract Article PDF–5.0M

Select item 105063979.

Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages

Megan Rowton, Carlos Perez-Cervantes, Suzy Hur, Jessica Jacobs-Li, Emery Lu, Nikita Deng, Alexander Guzzetta, Andrew D. Hoffmann, Matthew Stocker, Jeffrey D. Steimle, Sonja Lazarevic, Sophie Oubaha, Xinan H. Yang, Chul Kim, Shuhan Yu, Heather Eckart, Mervenaz Koska, Erika Hanson, Sunny S.K. Chan, Daniel J. Garry, Michael Kyba, Anindita Basu, Kohta Ikegami, Sebastian Pott, Ivan P. Moskowitz

Dev Cell. Author manuscript; available in PMC 2023 Sep 18.

Published in final edited form as: Dev Cell. 2022 Sep 26; 57(18): 2181–2203.e9. Published online 2022 Sep 14. doi: 10.1016/j.devcel.2022.08.009

PMCID:: PMC10506397

Abstract Article PDF–3.7M

Select item 1026668110.

Overlapping functions of SIX homeoproteins during embryonic myogenesis

Maud Wurmser, Rouba Madani, Nathalie Chaverot, Stéphanie Backer, Matthew Borok, Matthieu Dos Santos, Glenda Comai, Shahragim Tajbakhsh, Frédéric Relaix, Marc Santolini, Ramkumar Sambasivan, Rulang Jiang, Pascal Maire

PLoS Genet. 2023 Jun; 19(6): e1010781. Published online 2023 Jun 2. doi: 10.1371/journal.pgen.1010781

PMCID:: PMC10266681

Abstract Article PDF–4.6M

Select item 1024753311.

Multicellular rosettes link mesenchymal-epithelial transition to radial intercalation in the mouse axial mesoderm

Marissa L. Gredler, Jennifer A. Zallen

Dev Cell. Author manuscript; available in PMC 2023 Jun 8.

Published in final edited form as: Dev Cell. 2023 Jun 5; 58(11): 933–950.e5. Published online 2023 Apr 19. doi: 10.1016/j.devcel.2023.03.018

PMCID:: PMC10247533

Abstract Article PDF–2.3M

Select item 1016683612.

A genetic and developmental biological approach for a family with complex congenital heart diseases—evidence of digenic inheritance

Yu Yoshida, Keiko Uchida, Kazuki Kodo, Reina Ishizaki-Asami, Jun Maeda, Yoshinori Katsumata, Shinsuke Yuasa, Keiichi Fukuda, Kenjiro Kosaki, Yusuke Watanabe, Osamu Nakagawa, Hiroyuki Yamagishi

Front Cardiovasc Med. 2023; 10: 1135141. Published online 2023 Apr 25. doi: 10.3389/fcvm.2023.1135141

PMCID:: PMC10166836

Abstract Article PDF–18M

Select item 1011912113.

Topologically associating domain boundaries are required for normal genome function

Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li, Ana Alcaina Caro, Yoko Fukuda-Yuzawa, Guy Kelman, Adyam Akeza, Matthew J. Blow, Quan Pham, Anne N. Harrington, Janeth Godoy, Eman M. Meky, Kianna von Maydell, Riana D. Hunter, Jennifer A. Akiyama, Catherine S. Novak, Ingrid Plajzer-Frick, Veena Afzal, Stella Tran, Javier Lopez-Rios, Michael E. Talkowski, K. C. Kent Lloyd, Bing Ren, Diane E. Dickel, Axel Visel, Len A. Pennacchio

Commun Biol. 2023; 6: 435. Published online 2023 Apr 20. doi: 10.1038/s42003-023-04819-w

PMCID:: PMC10119121

Abstract Article PDF–3.2M

Select item 1008925214.

Pitx2 patterns an accelerator-brake mechanical feedback through latent TGFβ to rotate the gut

Bhargav D. Sanketi, Noam Zuela-Sopilniak, Elizabeth Bundschuh, Sharada Gopal, Shing Hu, Joseph Long, Jan Lammerding, Sevan Hopyan, Natasza A. Kurpios

Science. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Science. 2022 Sep 23; 377(6613): eabl3921. Published online 2022 Sep 23. doi: 10.1126/science.abl3921

PMCID:: PMC10089252

Abstract Article PDF–2.8M

Select item 988059715.

Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation

Kiya W. Govek, Sixing Chen, Paraskevi Sgourdou, Yao Yao, Steven Woodhouse, Tingfang Chen, Marc V. Fuccillo, Douglas J. Epstein, Pablo G. Camara

Cell Rep. Author manuscript; available in PMC 2023 Jan 27.

Published in final edited form as: Cell Rep. 2022 Dec 6; 41(10): 111768. doi: 10.1016/j.celrep.2022.111768

PMCID:: PMC9880597

Abstract Article PDF–2.4M

Select item 976575916.

TWIST1, a gene associated with Saethre-Chotzen syndrome, regulates extraocular muscle organization in mouse

Mary C. Whitman, Nicole M. Gilette, Jessica L. Bell, Seoyoung Kim, Max Tischfield, Elizabeth C. Engle

Dev Biol. Author manuscript; available in PMC 2022 Dec 20.

Published in final edited form as: Dev Biol. 2022 Oct; 490: 126–133. Published online 2022 Aug 6. doi: 10.1016/j.ydbio.2022.07.010

PMCID:: PMC9765759

Abstract Article PDF–2.1M

Select item 948197517.

Understanding the development of oral epithelial organs through single cell transcriptomic analysis

Qianlin Ye, Arshia Bhojwani, Jimmy K. Hu

Development. 2022 Aug 15; 149(16): dev200539. Published online 2022 Aug 17. doi: 10.1242/dev.200539

PMCID:: PMC9481975

Abstract Article

Select item 941891518.

HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis

Steven Eliason, Dan Su, Flavia Pinho, Zhao Sun, Zichao Zhang, Xiao Li, Mason Sweat, Shankar R. Venugopalan, Bing He, Michael Bustin, Brad A. Amendt

J Biol Chem. 2022 Sep; 298(9): 102295. Published online 2022 Jul 21. doi: 10.1016/j.jbc.2022.102295

PMCID:: PMC9418915

Abstract Article PDF–3.4M

Select item 929840819.

Pitx2 Differentially Regulates the Distinct Phases of Myogenic Program and Delineates Satellite Cell Lineages During Muscle Development

Felícitas Ramírez de Acuña, Francisco Hernandez-Torres, Lara Rodriguez-Outeiriño, Jorge N. Dominguez, Lidia Matias-Valiente, Cristina Sanchez-Fernandez, Diego Franco, Amelia E. Aranega

Front Cell Dev Biol. 2022; 10: 940622. Published online 2022 Jul 6. doi: 10.3389/fcell.2022.940622

PMCID:: PMC9298408

Abstract Article PDF–6.5M

Select item 929666620.

A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours

Akram A. Hamed, Daniel J. Kunz, Ibrahim El-Hamamy, Quang M. Trinh, Omar D. Subedar, Laura M. Richards, Warren Foltz, Garrett Bullivant, Matthaeus Ware, Maria C. Vladoiu, Jiao Zhang, Antony M. Raj, Trevor J. Pugh, Michael D. Taylor, Sarah A. Teichmann, Lincoln D. Stein, Benjamin D. Simons, Peter B. Dirks

Nat Commun. 2022; 13: 4178. Published online 2022 Jul 19. doi: 10.1038/s41467-022-31408-y

PMCID:: PMC9296666

Abstract Article PDF–11M

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PMC Links for GEO Profiles (Select 70604203) (310)
PMC
PREDICTED: Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 1C (P...
PREDICTED: Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 1C (PPP1R1C), transcript variant X1, mRNA
gi|1034612000|ref|XM_017003451.1|

Nucleotide
cytochrome c oxidase subunit I, partial (mitochondrion) [Lasius umbratus]
cytochrome c oxidase subunit I, partial (mitochondrion) [Lasius umbratus]
gi|2753196438|gb|XCI15864.1|

Protein
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 [Mus musculus]
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 [Mus musculus]
gi|225579120|ref|NP_067492.2|

Protein
Danio rerio polymerase (DNA directed), epsilon 2 (pole2), mRNA
Danio rerio polymerase (DNA directed), epsilon 2 (pole2), mRNA
gi|27545240|ref|NM_173246.1|

Nucleotide

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