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Items: 1 to 20 of 60

1.
Tead4 and Tfap2c generate bipotency and a bistable switch in totipotent embryos to promote robust lineage diversification
Meng Zhu, Maciej Meglicki, Adiyant Lamba, Peizhe Wang, Christophe Royer, Karen Turner, Muhammad Abdullah Jauhar, Celine Jones, Tim Child, Kevin Coward, Jie Na, Magdalena Zernicka-Goetz
Nat Struct Mol Biol. 2024; 31(6): 964–976. Published online 2024 May 24. doi: 10.1038/s41594-024-01311-9
PMCID:
PMC11189297
AbstractArticlePDF–6.5M
2.
HN1L/AP-2γ/PLK1 signaling drives tumor progression and chemotherapy resistance in esophageal squamous cell carcinoma
Ting-Ting Zeng, Tian-Hao Deng, Zhen Liu, Jia-Rong Zhan, Yuan-Zhen Ma, Yuan-Yuan Yan, Xiao Sun, Ying-Hui Zhu, Yan Li, Xin-Yuan Guan, Lei Li
Cell Death Dis. 2022 Dec; 13(12): 1026. Published online 2022 Dec 7. doi: 10.1038/s41419-022-05478-1
PMCID:
PMC9729194
AbstractArticlePDF–8.6M
3.
Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA)
Yifei Zhang, Asal AA Mostafa, Natthida Sriboonvorakul, Jiamiao Hu
Medicine (Baltimore) 2022 Sep 23; 101(38): e30587. Published online 2022 Sep 23. doi: 10.1097/MD.0000000000030587
PMCID:
PMC9509159
AbstractArticlePDF–500K
4.
TRIM37 Augments AP-2γ Transcriptional Activity and Cellular Localization via K63-linked Ubiquitination to Drive Breast Cancer Progression
Guimei Cui, Zhuoran Gao, Shiehong Chang, Nitin Narwade, Yitian Chen, Barun Poudel, Kate M. K. Lei, Weibo Zhang, Gang Li, Terence C. W. Poon, Edwin Cheung
Int J Biol Sci. 2022; 18(11): 4316–4328. Published online 2022 Jul 4. doi: 10.7150/ijbs.69466
PMCID:
PMC9295074
AbstractArticlePDF–2.7M
5.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
6.
Fucosyltransferase 8 regulation and breast cancer suppression by transcription factor activator protein 2γ
Minxing Ma, Dong Guo, Zengqi Tan, Jun Du, Feng Guan, Xiang Li
Cancer Sci. 2021 Aug; 112(8): 3190–3204. Published online 2021 Jun 12. doi: 10.1111/cas.14987
PMCID:
PMC8353918
AbstractArticlePDF–3.4M
7.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
Interaction of transcription factor AP‐2 gamma with proto‐oncogene PELP1 promotes tumorigenesis by enhancing RET signaling
Junhao Liu, Zexuan Liu, Mengxing Li, Weiwei Tang, Uday P. Pratap, Yiliao Luo, Kristin A. Altwegg, Xiaonan Li, Yi Zou, Hong Zhu, Gangadhara R. Sareddy, Suryavathi Viswanadhapalli, Ratna K. Vadlamudi
Mol Oncol. 2021 Apr; 15(4): 1146–1161. Published online 2021 Feb 9. doi: 10.1002/1878-0261.12871
Correction in:
Mol Oncol. 2022 Jan; 16(1): 307.
PMCID:
PMC8024722
AbstractArticlePDF–2.5M
10.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
11.
Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu
NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3
PMCID:
PMC7979705
AbstractArticlePDF–6.8M
12.
GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program
Yoji Kojima, Chika Yamashiro, Yusuke Murase, Yukihiro Yabuta, Ikuhiro Okamoto, Chizuru Iwatani, Hideaki Tsuchiya, Masataka Nakaya, Tomoyuki Tsukiyama, Tomonori Nakamura, Takuya Yamamoto, Mitinori Saitou
Life Sci Alliance. 2021 May; 4(5): e202000974. Published online 2021 Feb 19. doi: 10.26508/lsa.202000974
PMCID:
PMC7918644
AbstractArticlePDF–4.6M
13.
Functional genomics of AP-2α and AP-2γ in cancers: in silico study
Damian Kołat, Żaneta Kałuzińska, Magdalena Orzechowska, Andrzej K. Bednarek, Elżbieta Płuciennik
BMC Med Genomics. 2020; 13: 174. Published online 2020 Nov 19. doi: 10.1186/s12920-020-00823-9
PMCID:
PMC7678100
AbstractArticlePDF–7.2M
14.
METTL3 potentiates resistance to cisplatin through m6A modification of TFAP2C in seminoma
Jingchao Wei, Yinghao Yin, Jun Zhou, Hanfei Chen, Jingxuan Peng, Jianfu Yang, Yuxin Tang
J Cell Mol Med. 2020 Oct; 24(19): 11366–11380. Published online 2020 Aug 28. doi: 10.1111/jcmm.15738
PMCID:
PMC7576266
AbstractArticlePDF–1.8M
15.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
16.
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer
Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid, Isaac S. Harris, Bojana Jovanović, Katherine Murphy, Binbin Wang, Xintao Qiu, Jennifer E. Endress, Jaime Reyes, Klothilda Lim, Alba Font-Tello, Sudeepa Syamala, Tengfei Xiao, Chandra Sekhar Reddy Chilamakuri, Evangelia K. Papachristou, Clive D’Santos, Jayati Anand, Kunihiko Hinohara, Wei Li, Thomas O. McDonald, Adrienne Luoma, Rebecca J. Modiste, Quang-De Nguyen, Brittany Michel, Paloma Cejas, Cigall Kadoch, Jacob D. Jaffe, Kai W. Wucherpfennig, Jun Qi, X. Shirley Liu, Henry Long, Myles Brown, Jason S. Carroll, Joan S. Brugge, James Bradner, Franziska Michor, Kornelia Polyak
Mol Cell. Author manuscript; available in PMC 2021 Jun 18.
Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1096–1113.e8. Published online 2020 May 15. doi: 10.1016/j.molcel.2020.04.027
PMCID:
PMC7306005
AbstractArticlePDF–3.2M
17.
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment
Lingjie Li, Yong Wang, Jessica L. Torkelson, Gautam Shankar, Jillian M. Pattison, Hanson H. Zhen, Fengqin Fang, Zhana Duren, Jingxue Xin, Sadhana Gaddam, Sandra P. Melo, Samantha N. Piekos, Jiang Li, Eric J. Liaw, Lang Chen, Rui Li, Marius Wernig, Wing H. Wong, Howard Y. Chang, Anthony E. Oro
Cell Stem Cell. Author manuscript; available in PMC 2020 Apr 6.
Published in final edited form as: Cell Stem Cell. 2019 Feb 7; 24(2): 271–284.e8. Published online 2019 Jan 24. doi: 10.1016/j.stem.2018.12.012
PMCID:
PMC7135956
AbstractArticlePDF–4.1M
18.
Endogenous purification reveals GREB1 as a key Estrogen Receptor regulatory factor
Hisham Mohammed, Clive D’Santos, Aurelien A. Serandour, H. Raza Ali, Gordon. D. Brown, Alan Atkins, Oscar M. Rueda, Kelly A Holmes, Vasiliki Theodorou, Jessica L. L. Robinson, Wilbert Zwart, Amel Saadi, Caryn S. Ross-Innes, Suet-Feung Chin, Suraj Menon, John Stingl, Carlo Palmieri, Carlos Caldas, Jason S. Carroll
Cell Rep. Author manuscript; available in PMC 2021 Jan 29.
Published in final edited form as: Cell Rep. 2013 Feb 21; 3(2): 342–9. Published online 2013 Feb 9. doi: 10.1016/j.celrep.2013.01.010
PMCID:
PMC7116645
AbstractArticlePDF–1.5M
19.
Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions
Danielle Park, Esther Wershof, Stefan Boeing, Anna Labernadie, Robert P Jenkins, Samantha George, Xavier Trepat, Paul A Bates, Erik Sahai
Nat Mater. Author manuscript; available in PMC 2020 Apr 28.
Published in final edited form as: Nat Mater. 2020 Feb; 19(2): 227–238. Published online 2019 Oct 28. doi: 10.1038/s41563-019-0504-3
PMCID:
PMC6989216
AbstractArticlePDF–4.2M
20.
A TFAP2C Gene Signature is Predictive of Outcome in HER2-positive Breast Cancer
Vincent T. Wu, Boris Kiriazov, Kelsey E. Koch, Vivian W. Gu, Anna C. Beck, Nicholas Borcherding, Tiandao Li, Peter Addo, Zachary J. Wehrspan, Weizhou Zhang, Terry A. Braun, Bartley J. Brown, Vimla Band, Hamid Band, Mikhail V. Kulak, Ronald J. Weigel
Mol Cancer Res. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Mol Cancer Res. 2020 Jan; 18(1): 46–56. Published online 2019 Oct 16. doi: 10.1158/1541-7786.MCR-19-0359
PMCID:
PMC6942205
AbstractArticlePDF–1.6M

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