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Items: 1 to 20 of 33

1.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
2.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
3.
Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation
Joshua C Bufton, Kyle T Powers, Jenn-Yeu A Szeto, Christine Toelzer, Imre Berger, Christiane Schaffitzel
Nucleic Acids Res. 2022 Jun 10; 50(10): 5934–5947. Published online 2022 May 31. doi: 10.1093/nar/gkac421
PMCID:
PMC9177958
AbstractArticlePDF–2.7M
4.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
5.
Mammalian UPF3A and UPF3B can activate nonsense‐mediated mRNA decay independently of their exon junction complex binding
Zhongxia Yi, René M Arvola, Sean Myers, Corinne N Dilsavor, Rabab Abu Alhasan, Bayley N Carter, Robert D Patton, Ralf Bundschuh, Guramrit Singh
EMBO J. 2022 May; 41(10): e109202. Published online 2022 Apr 22. doi: 10.15252/embj.2021109202
PMCID:
PMC9108626
AbstractArticlePDF–2.4M
6.
Human UPF3A and UPF3B enable fault‐tolerant activation of nonsense‐mediated mRNA decay
Damaris Wallmeroth, Jan‐Wilm Lackmann, Sabrina Kueckelmann, Janine Altmüller, Christoph Dieterich, Volker Boehm, Niels H Gehring
EMBO J. 2022 May; 41(10): e109191. Published online 2022 Apr 22. doi: 10.15252/embj.2021109191
PMCID:
PMC9108619
AbstractArticlePDF–2.4M
7.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9
PMCID:
PMC7910459
AbstractArticlePDF–3.3M
10.
(Phospho)proteomic Profiling of Microsatellite Unstable CRC Cells Reveals Alterations in Nuclear Signaling and Cholesterol Metabolism Caused by Frameshift Mutation of NMD Regulator UPF3A
Malwina Michalak, Eva-Maria Katzenmaier, Nina Roeckel, Stefan M. Woerner, Vera Fuchs, Uwe Warnken, Yan P. Yuan, Peer Bork, Gabriele Neu-Yilik, Andreas Kulozik, Magnus von Knebel Doeberitz, Matthias Kloor, Jürgen Kopitz, Johannes Gebert
Int J Mol Sci. 2020 Aug; 21(15): 5234. Published online 2020 Jul 23. doi: 10.3390/ijms21155234
PMCID:
PMC7432364
AbstractArticlePDF–2.6M
11.
Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative and HER2-enriched breast cancers
Sherona R. Sirkisoon, Richard L. Carpenter, Tadas Rimkus, Ashley Anderson, Alexandria Harrison, Allison M. Lange, Guangxu Jin, Kounosuke Watabe, Hui-Wen Lo
Oncogene. Author manuscript; available in PMC 2018 Aug 16.
Published in final edited form as: Oncogene. 2018 May; 37(19): 2502–2514. Published online 2018 Feb 16. doi: 10.1038/s41388-018-0132-4
Correction in:
Oncogene. 2024 Jun 12
PMCID:
PMC5948110
AbstractArticlePDF–1.1M
12.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
13.
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers
Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn
Cell Syst. Author manuscript; available in PMC 2017 Sep 28.
Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001
PMCID:
PMC5455996
AbstractArticlePDF–3.1M
14.
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning
Koray Kırlı, Samir Karaca, Heinz Jürgen Dehne, Matthias Samwer, Kuan Ting Pan, Christof Lenz, Henning Urlaub, Dirk Görlich
eLife. 2015; 4: e11466. Published online 2015 Dec 17. doi: 10.7554/eLife.11466
PMCID:
PMC4764573
AbstractArticlePDF–5.7M
15.
The RNA Helicase DHX34 Activates NMD by Promoting a Transition from the Surveillance to the Decay-Inducing Complex
Nele Hug, Javier F. Cáceres
Cell Rep. 2014 Sep 25; 8(6): 1845–1856. Published online 2014 Sep 15. doi: 10.1016/j.celrep.2014.08.020
PMCID:
PMC4534575
AbstractArticlePDF–2.5M
16.
Development and application of a DNA microarray-based yeast two-hybrid system
Bernhard Suter, Jean-Fred Fontaine, Reha Yildirimman, Tamás Raskó, Martin H. Schaefer, Axel Rasche, Pablo Porras, Blanca M. Vázquez-Álvarez, Jenny Russ, Kirstin Rau, Raphaele Foulle, Martina Zenkner, Kathrin Saar, Ralf Herwig, Miguel A. Andrade-Navarro, Erich E. Wanker
Nucleic Acids Res. 2013 Feb; 41(3): 1496–1507. Published online 2012 Dec 26. doi: 10.1093/nar/gks1329
PMCID:
PMC3561971
AbstractArticlePDF–8.6M
17.
Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense-mediated mRNA decay
Tobias M. Franks, Guramrit Singh, Jens Lykke-Andersen
Cell. Author manuscript; available in PMC 2012 May 21.
Published in final edited form as: Cell. 2010 Dec 10; 143(6): 938–950. doi: 10.1016/j.cell.2010.11.043
PMCID:
PMC3357093
AbstractArticlePDF–5.5M
18.
Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN
Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi
J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907
PMCID:
PMC3190826
AbstractArticlePDF–5.7M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
A Yeast Model of FUS/TLS-Dependent Cytotoxicity
Shulin Ju, Daniel F. Tardiff, Haesun Han, Kanneganti Divya, Quan Zhong, Lynne E. Maquat, Daryl A. Bosco, Lawrence J. Hayward, Robert H. Brown, Jr., Susan Lindquist, Dagmar Ringe, Gregory A. Petsko
PLoS Biol. 2011 Apr; 9(4): e1001052. Published online 2011 Apr 26. doi: 10.1371/journal.pbio.1001052
PMCID:
PMC3082520
AbstractArticlePDF–837K

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