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Select item 111548371.

MST1 knockdown inhibits osteoarthritis progression through Parkin‐mediated mitophagy and Nrf2/NF‐κB signalling pathway

Hantao Ye, Tingwen Cai, Yang Shen, Lin Zhao, Haojie Zhang, Jianxin Yang, Feida Li, Jiaoxiang Chen, Xiaolong Shui

J Cell Mol Med. 2024 Jun; 28(11): e18476. Published online 2024 Jun 6. doi: 10.1111/jcmm.18476

PMCID:: PMC11154837

Abstract Article PDF–31M

Select item 109849672.

The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress

Dae Jin Jeong, Jee-Hyun Um, Young Yeon Kim, Dong Jin Shin, Sangwoo Im, Kang-Min Lee, Yun-Hee Lee, Dae-sik Lim, Donghoon Kim, Jeanho Yun

Exp Mol Med. 2024 Mar; 56(3): 674–685. Published online 2024 Mar 5. doi: 10.1038/s12276-024-01198-y

PMCID:: PMC10984967

Abstract Article PDF–4.8M

Select item 106964033.

Smurf1 polyubiquitinates on K285/K282 of the kinases Mst1/2 to attenuate their tumor-suppressor functions

Yana Xu, Meiyu Qu, Yangxun He, Qiangqiang He, Tingyu Shen, Jiahao Luo, Dan Tan, Hangyang Bao, Chengyun Xu, Xing Ji, Xinhua Hu, Muhammad Qasim Barkat, Ling-Hui Zeng, Ximei Wu

J Biol Chem. 2023 Dec; 299(12): 105395. Published online 2023 Oct 27. doi: 10.1016/j.jbc.2023.105395

PMCID:: PMC10696403

Abstract Article PDF–5.4M

Select item 106377894.

STK4 is a prognostic biomarker correlated with immune infiltrates in clear cell renal cell carcinoma

Zi-Yuan Bai, Lu-Shan Peng, Run-Qi Li, Xianchu Peng, Zhe Yang

Aging (Albany NY) 2023 Oct 31; 15(20): 11286–11297. Published online 2023 Oct 20. doi: 10.18632/aging.205127

PMCID:: PMC10637789

Abstract Article PDF–1.6M

Select item 104805355.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100729067.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 99501838.

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini

Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3

PMCID:: PMC9950183

Abstract Article PDF–2.4M

Select item 98094939.

LncRNA GAS5 enhances tumor stem cell-like medicated sensitivity of paclitaxel and inhibits epithelial-to-mesenchymal transition by targeting the miR-18a-5p/STK4 pathway in prostate cancer

Ting-Ting Lu, Xia Tao, Hua-Lei Li, Ling Gai, Hua Huang, Feng Li

Asian J Androl. 2022 Nov-Dec; 24(6): 643–652. Published online 2022 Mar 15. doi: 10.4103/aja2021117

PMCID:: PMC9809493

Abstract Article PDF–3.2M

Select item 976969810.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 968816011.

Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington’s Disease and Other Neurodegenerative Disorders

Pasquale Sileo, Clémence Simonin, Patricia Melnyk, Marie-Christine Chartier-Harlin, Philippe Cotelle

Cells. 2022 Nov; 11(22): 3631. Published online 2022 Nov 16. doi: 10.3390/cells11223631

PMCID:: PMC9688160

Abstract Article PDF–1.8M

Select item 957567312.

Deficiency of MST1 in endometriosis related peritoneal macrophages promoted the autophagy of ectopic endometrial stromal cells by IL-10

Yufei Huang, Shumin Yan, Xiaoyu Dong, Xue Jiao, Shuang Wang, Dong Li, Guoyun Wang

Front Immunol. 2022; 13: 993788. Published online 2022 Oct 3. doi: 10.3389/fimmu.2022.993788

PMCID:: PMC9575673

Abstract Article PDF–10M

Select item 954043413.

Regulation of MST complexes and activity via SARAH domain modifications

Sofiia Karchugina, Dorothy Benton, Jonathan Chernoff

Biochem Soc Trans. Author manuscript; available in PMC 2022 Oct 7.

Published in final edited form as: Biochem Soc Trans. 2021 Apr 30; 49(2): 675–683. doi: 10.1042/BST20200559

PMCID:: PMC9540434

Abstract Article PDF–485K

Select item 948193314.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 927928515.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 911973616.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 905883617.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 902294418.

The Hippo pathway kinases LATS1 and 2 attenuate cellular responses to heavy metals through phosphorylating MTF1

Han Han, Hiroki J Nakaoka, Line Hofmann, Jeff Jiajing Zhou, Clinton Yu, Lisha Zeng, Junyu Nan, Gayoung Seo, Rebecca Elizabeth Vargas, Bing Yang, Ruxi Qi, Lee Bardwell, Dmitry A. Fishman, Ken W.Y. Cho, Lan Huang, Ray Luo, Rahul Warrior, Wenqi Wang

Nat Cell Biol. Author manuscript; available in PMC 2022 Jul 13.

Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 74–87. Published online 2022 Jan 13. doi: 10.1038/s41556-021-00813-8

PMCID:: PMC9022944

Abstract Article PDF–8.9M

Select item 893307519.

Circular RNA_0057209 Acts as ceRNA to Inhibit Thyroid Cancer Progression by Promoting the STK4-Mediated Hippo Pathway via Sponging MicroRNA-183

Xinzhi Peng, Yue Zhu, Shaojian Lin, Weiming Yu, Cheng Zhang, Langping Tan, Miaoyun Long, Dingyuan Luo, Chengcheng Ji

Oxid Med Cell Longev. 2022; 2022: 9974639. Published online 2022 Mar 11. doi: 10.1155/2022/9974639

PMCID:: PMC8933075

Abstract Article PDF–3.1M

Select item 889702220.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

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