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Select item 110344931.

Inhibition of SUV39H1 reduces tumor angiogenesis via Notch1 in oral squamous cell carcinoma

Yan Chen, Xiuhong Weng, Chuanjie Zhang, Simin Wang, Xuechen Wu, Bo Cheng

PeerJ. 2024; 12: e17222. Published online 2024 Apr 19. doi: 10.7717/peerj.17222

PMCID:: PMC11034493

Abstract Article PDF–12M

Select item 106831032.

SUV39H1 is a novel biomarker targeting oxidative phosphorylation in hepatitis B virus-associated hepatocellular carcinoma

Yanping Zhang, Wanwen Lao, Kaming Yang, Xinyi Kong, Yuetong Li, Xin Yu, Xumeng Wang, Yang Liu, Zhenlin Li, Yilin Deng, Shuping Nie, Changlong Bi, Chao Wu, Aixia Zhai

BMC Cancer. 2023; 23: 1159. Published online 2023 Nov 28. doi: 10.1186/s12885-023-11633-4

PMCID:: PMC10683103

Abstract Article PDF–7.3M

Select item 97647403.

Decreased SUV39H1 at the promoter region leads to increased CREMα and accelerates autoimmune response in CD4⁺ T cells from patients with systemic lupus erythematosus

Shuangyan Luo, Huilin Zhang, Yuming Xie, Junke Huang, Danhong Luo, Qing Zhang

Clin Epigenetics. 2022; 14: 181. Published online 2022 Dec 20. doi: 10.1186/s13148-022-01411-7

PMCID:: PMC9764740

Abstract Article PDF–3.5M

Select item 95403454.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 94917135.

FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ

Hua Jiang, Weixiang Bian, Yue Sui, Huanle Li, Han Zhao, Wenqi Wang, Xu Li

Sci Adv. 2022 Sep; 8(38): eabq4831. Published online 2022 Sep 21. doi: 10.1126/sciadv.abq4831

PMCID:: PMC9491713

Abstract Article PDF–12M

Select item 92430056.

CD8+T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas

Leticia Laura Niborski, Paul Gueguen, Mengliang Ye, Allan Thiolat, Rodrigo Nalio Ramos, Pamela Caudana, Jordan Denizeau, Ludovic Colombeau, Raphaël Rodriguez, Christel Goudot, Jean-Michel Luccarini, Anne Soudé, Bruno Bournique, Pierre Broqua, Luigia Pace, Sylvain Baulande, Christine Sedlik, Jean-Pierre Quivy, Geneviève Almouzni, José L. Cohen, Elina Zueva, Joshua J. Waterfall, Sebastian Amigorena, Eliane Piaggio

Nat Commun. 2022; 13: 3739. Published online 2022 Jun 29. doi: 10.1038/s41467-022-31504-z

Correction in:: Nat Commun. 2023; 14: 3127.

PMCID:: PMC9243005

Abstract Article PDF–4.5M

Select item 91197367.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 86090218.

Histone Mark Profiling in Pediatric Astrocytomas Reveals Prognostic Significance of H3K9 Trimethylation and Histone Methyltransferase SUV39H1

Alexia Klonou, Penelope Korkolopoulou, Antonios N. Gargalionis, Dimitrios S. Kanakoglou, Hector Katifelis, Maria Gazouli, Sarantis Chlamydas, Andreas Mitsios, Theodosis Kalamatianos, George Stranjalis, Marios S. Themistocleous, Kostas A. Papavassiliou, Spyros Sgouros, Athanasios G. Papavassiliou, Christina Piperi

Neurotherapeutics. 2021 Jul; 18(3): 2073–2090. Published online 2021 Jul 22. doi: 10.1007/s13311-021-01090-x

PMCID:: PMC8609021

Abstract Article PDF–2.9M

Select item 85017969.

PRAMEF2-mediated dynamic regulation of YAP signaling promotes tumorigenesis

Madhurima Ghosh, Sanjeev Das

Proc Natl Acad Sci U S A. 2021 Oct 5; 118(40): e2105523118. Published online 2021 Sep 30. doi: 10.1073/pnas.2105523118

PMCID:: PMC8501796

Abstract Article PDF–2.6M

Select item 848716010.

Suppressor of variegation 3–9 homologue 1 impairment and neutrophil-skewed systemic inflammation are associated with comorbidities in COPD

Tzu-Tao Chen, Sheng-Ming Wu, Kuan-Yuan Chen, Chien-Hua Tseng, Shu-Chuan Ho, Hsiao-Chi Chuang, Po-Hao Feng, Wen-Te Liu, Chia-Li Han, Erick Wan-Chun Huang, Yun-Kai Yeh, Kang-Yun Lee

BMC Pulm Med. 2021; 21: 276. Published online 2021 Oct 2. doi: 10.1186/s12890-021-01628-x

PMCID:: PMC8487160

Abstract Article PDF–1.6M

Select item 841104411.

EBP1 regulates Suv39H1 stability via the ubiquitin-proteasome system in neural development

Byeong-Seong Kim, Hyo Rim Ko, Inwoo Hwang, Sung-Woo Cho, Jee-Yin Ahn

BMB Rep. 2021 Aug 31; 54(8): 413–418. Published online 2021 Aug 31. doi: 10.5483/BMBRep.2021.54.8.022

PMCID:: PMC8411044

Abstract Article PDF–4.3M

Select item 826661712.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 810625314.

Downregulation of SUV39H1 and CITED2 Exerts Additive Effect on Promoting Adipogenic Commitment of Human Mesenchymal Stem Cells

Lun Tan, Linh Tran, Stephanie Ferreyra, Jose A. Moran, Zachary Skovgaard, Amparo Trujillo, Esra ibili, Yuanxiang Zhao

Stem Cells Dev. May 2021; 30(9): 485–501. Published online 2021 May 3. doi: 10.1089/scd.2020.0190

PMCID:: PMC8106253

Abstract Article PDF–1.5M

Select item 804325215.

FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

Jia Z. Shen, Zhixin Qiu, Qiulian Wu, Darren Finlay, Guillermina Garcia, Dahui Sun, Juha Rantala, William Barshop, Jennifer L. Hope, Ryan C. Gimple, Olle Sangfelt, Linda M. Bradley, James Wohlschlegel, Jeremy N. Rich, Charles Spruck

Cell. Author manuscript; available in PMC 2021 Apr 13.

Published in final edited form as: Cell. 2021 Jan 21; 184(2): 352–369.e23. Published online 2020 Dec 23. doi: 10.1016/j.cell.2020.11.042

PMCID:: PMC8043252

Abstract Article PDF–3.8M

Select item 776235116.

Effect of SUV39H1 Histone Methyltransferase Knockout on Expression of Differentiation-Associated Genes in HaCaT Keratinocytes

Barbara Sobiak, Wiesława Leśniak

Cells. 2020 Dec; 9(12): 2628. Published online 2020 Dec 7. doi: 10.3390/cells9122628

PMCID:: PMC7762351

Abstract Article PDF–1.7M

Select item 772859717.

SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia

Yajing Chu, Yangpeng Chen, Huidong Guo, Mengke Li, Bichen Wang, Deyang Shi, Xuelian Cheng, Jinxia Guan, Xiaomin Wang, Chenghai Xue, Tao Cheng, Jun Shi, Weiping Yuan

Oncogene. 2020; 39(50): 7239–7252. Published online 2020 Oct 9. doi: 10.1038/s41388-020-01495-6

PMCID:: PMC7728597

Abstract Article PDF–3.9M

Select item 756688118.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 716998319.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 713863120.

SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth

Chunwan Lu, John D. Klement, Dafeng Yang, Thomas Albers, Iryna O. Lebedyeva, Jennifer L. Waller, Kebin Liu

Cancer Lett. Author manuscript; available in PMC 2021 Apr 28.

Published in final edited form as: Cancer Lett. 2020 Apr 28; 476: 87–96. Published online 2020 Feb 12. doi: 10.1016/j.canlet.2020.02.004

PMCID:: PMC7138631

Abstract Article PDF–2.2M

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