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Items: 1 to 20 of 80

1.
Neurokinin-1 receptor is highly expressed in cervical cancer and its antagonist induces cervical cancer cell apoptosis
Liyun Guan, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang
Eur J Histochem. 2023 Jan 2; 67(1): 3570. Published online 2023 Jan 11. doi: 10.4081/ejh.2023.3570
PMCID:
PMC10300428
AbstractArticlePDF–845K
2.
Involvement of Substance P (SP) and Its Related NK1 Receptor in Primary Sjögren’s Syndrome (pSS) Pathogenesis
Pamela Rosso, Elena Fico, Serena Colafrancesco, Mario Giuseppe Bellizzi, Roberta Priori, Bruna Cerbelli, Martina Leopizzi, Carla Giordano, Antonio Greco, Paola Tirassa, Cinzia Severini, Massimo Fusconi
Cells. 2023 May; 12(10): 1347. Published online 2023 May 9. doi: 10.3390/cells12101347
PMCID:
PMC10216552
AbstractArticlePDF–2.0M
3.
Upregulated expression of substance P and NK1R in blood monocytes and B cells of patients with allergic rhinitis and asthma
Peixuan Han, Liping Chen, Dong Chen, Ruiming Yang, Wei Wang, Jingyu Liu, Shaoheng He, Huiyun Zhang
Clin Exp Immunol. 2022 Oct; 210(1): 39–52. Published online 2022 Aug 24. doi: 10.1093/cei/uxac074
PMCID:
PMC9585549
AbstractArticlePDF–1.9M
4.
Substance P promotes the progression of bronchial asthma through activating the PI3K/AKT/NF-κB pathway mediated cellular inflammation and pyroptotic cell death in bronchial epithelial cells
Miao Li, Xiao Zhong, Wen-Ting Xu
Cell Cycle. 2022; 21(20): 2179–2191. Published online 2022 Jun 26. doi: 10.1080/15384101.2022.2092166
PMCID:
PMC9519020
AbstractArticlePDF–3.6M
5.
A Substance P (SP)/Neurokinin-1 Receptor Axis Promotes Perineural Invasion of Pancreatic Cancer and Is Affected by lncRNA LOC389641
Tengfei Ji, Keqiang Ma, Hongsheng Wu, Tiansheng Cao
J Immunol Res. 2022; 2022: 5582811. Published online 2022 May 12. doi: 10.1155/2022/5582811
PMCID:
PMC9119758
AbstractArticlePDF–6.3M
6.
The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma
Mario F. Muñoz, Sandro Argüelles, Marisa Rosso, Rafael Medina, Rafael Coveñas, Antonio Ayala, Miguel Muñoz
Biomed Res Int. 2022; 2022: 6291504. Published online 2022 Apr 4. doi: 10.1155/2022/6291504
PMCID:
PMC9006081
AbstractArticlePDF–2.4M
7.
Neurokinin-1 receptor signaling induces a pro-inflammatory transcriptomic profile in CD16+ monocytes
Vasiliki Pappa, Sergei Spitsin, Peter J. Gaskill, Steven D. Douglas
J Neuroimmunol. Author manuscript; available in PMC 2022 Apr 7.
Published in final edited form as: J Neuroimmunol. 2021 Apr 15; 353: 577524. Published online 2021 Feb 20. doi: 10.1016/j.jneuroim.2021.577524
PMCID:
PMC8988161
AbstractArticlePDF–1.1M
8.
The Neurokinin-1 Receptor Is a Target in Pediatric Rhabdoid Tumors
Julian Kolorz, Salih Demir, Adrian Gottschlich, Iris Beirith, Matthias Ilmer, Daniel Lüthy, Christoph Walz, Mario M. Dorostkar, Thomas Magg, Fabian Hauck, Dietrich von Schweinitz, Sebastian Kobold, Roland Kappler, Michael Berger
Curr Oncol. 2022 Jan; 29(1): 94–110. Published online 2021 Dec 26. doi: 10.3390/curroncol29010008
PMCID:
PMC8775224
AbstractArticlePDF–2.9M
9.
Neurokinin-1 receptor promotes non-small cell lung cancer progression through transactivation of EGFR
Xiao-Wei Zhang, Lin Li, Wen-Qian Hu, Ming-Ning Hu, Yan Tao, Hui Hu, Xiao-Kang Miao, Wen-Le Yang, Qiong Zhu, Ling-Yun Mou
Cell Death Dis. 2022 Jan; 13(1): 41. Published online 2022 Jan 10. doi: 10.1038/s41419-021-04485-y
PMCID:
PMC8748918
AbstractArticlePDF–7.5M
10.
Prognostic Significance of Substance P/Neurokinin 1 Receptor and Its Association with Hormonal Receptors in Breast Carcinoma
Riffat Mehboob, Syed Amir Gilani, Amber Hassan, Sadaf, Imrana Tanvir, Shaista Javaid, Sidra Khalid, Sana Hasan, Humaira Waseem, Ahmad Alwazzan, Miguel Munoz
Biomed Res Int. 2021; 2021: 5577820. Published online 2021 Oct 13. doi: 10.1155/2021/5577820
PMCID:
PMC8528600
AbstractArticlePDF–1.5M
11.
Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-κB Signal Transduction Pathways in Colon Cancer Cells
Atefeh Ghahremanloo, Hossein Javid, Amir R. Afshari, Seyed Isaac Hashemy
Biomed Res Int. 2021; 2021: 1383878. Published online 2021 Aug 2. doi: 10.1155/2021/1383878
PMCID:
PMC8355960
AbstractArticlePDF–996K
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
The neuropeptide substance P regulates aldosterone secretion in human adrenals
Julien Wils, Céline Duparc, Anne-Françoise Cailleux, Antoine-Guy Lopez, Caroline Guiheneuf, Isabelle Boutelet, Hadrien-Gaël Boyer, Christophe Dubessy, Saloua Cherifi, Bruno Cauliez, Françoise Gobet, Guillaume Defortescu, Jean-François Ménard, Estelle Louiset, Hervé Lefebvre
Nat Commun. 2020; 11: 2673. Published online 2020 May 29. doi: 10.1038/s41467-020-16470-8
PMCID:
PMC7260184
AbstractArticlePDF–6.0M
14.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
15.
Neurokinin Receptors in Drug and Alcohol Addiction
Jesse R. Schank
Brain Res. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Brain Res. 2020 May 1; 1734: 146729. Published online 2020 Feb 15. doi: 10.1016/j.brainres.2020.146729
PMCID:
PMC7138066
AbstractArticlePDF–328K
16.
SP/NK‐1R promotes gallbladder cancer cell proliferation and migration
Xue‐Ting Deng, Si‐Min Tang, Pei‐Yao Wu, Quan‐Peng Li, Xian‐Xiu Ge, Bo‐Ming Xu, Hui‐Shan Wang, Lin Miao
J Cell Mol Med. 2019 Dec; 23(12): 7961–7973. Published online 2019 Mar 22. doi: 10.1111/jcmm.14230
PMCID:
PMC6850939
AbstractArticlePDF–3.2M
17.
LncRNA RMRP silence curbs neonatal neuroblastoma progression by regulating microRNA-206/tachykinin-1 receptor axis via inactivating extracellular signal-regulated kinases
Juntao Pan, Da Zhang, Jiao Zhang, Pan Qin, Jiaxiang Wang
Cancer Biol Ther. 2019; 20(5): 653–665. Published online 2018 Dec 24. doi: 10.1080/15384047.2018.1550568
PMCID:
PMC6606040
AbstractArticlePDF–2.5M
18.
MiR‐34b/c‐5p and the neurokinin‐1 receptor regulate breast cancer cell proliferation and apoptosis
Lufang Zhang, Lushan Wang, Dong Dong, Zhiyong Wang, Wei Ji, Man Yu, Fei Zhang, Ruifang Niu, Yunli Zhou
Cell Prolif. 2019 Jan; 52(1): e12527. Published online 2018 Oct 17. doi: 10.1111/cpr.12527
PMCID:
PMC6430481
AbstractArticlePDF–1.7M
19.
Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists
Jendrik Schöppe, Janosch Ehrenmann, Christoph Klenk, Prakash Rucktooa, Marco Schütz, Andrew S. Doré, Andreas Plückthun
Nat Commun. 2019; 10: 17. Published online 2019 Jan 3. doi: 10.1038/s41467-018-07939-8
PMCID:
PMC6318301
AbstractArticlePDF–1.9M
20.
Crystal structure of the human NK1 tachykinin receptor
Jie Yin, Karen Chapman, Lindsay D. Clark, Zhenhua Shao, Dominika Borek, Qingping Xu, Junmei Wang, Daniel M. Rosenbaum
Proc Natl Acad Sci U S A. 2018 Dec 26; 115(52): 13264–13269. Published online 2018 Dec 11. doi: 10.1073/pnas.1812717115
PMCID:
PMC6310836
AbstractArticlePDF–1.1M

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