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Select item 111600751.

Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer

Takeshi Tsuchiya, Yurai Okaji, Nelson H. Tsuno, Daisuke Sakurai, Naoyuki Tsuchiya, Kazushige Kawai, Kentaro Yazawa, Masahiro Asakage, Jun Yamada, Satomi Yoneyama, Joji Kitayama, Takuya Osada, Toshiaki Watanabe, Katsushi Tokunaga, Koki Takahashi, Hirokazu Nagawa

Cancer Sci. 2005 Nov; 96(11): 784–790. Published online 2005 Nov 4. doi: 10.1111/j.1349-7006.2005.00113.x

PMCID:: PMC11160075

Abstract Article PDF–200K

Select item 108813992.

The nuclear factor ID3 endows macrophages with a potent anti-tumour activity

Zihou Deng, Pierre-Louis Loyher, Tomi Lazarov, Li Li, Zeyang Shen, Bhavneet Bhinder, Hairu Yang, Yi Zhong, Araitz Alberdi, Joan Massague, Joseph C. Sun, Robert Benezra, Christopher K. Glass, Olivier Elemento, Christine A. Iacobuzio-Donahue, Frederic Geissmann

Nature. 2024; 626(8000): 864–873. Published online 2024 Feb 7. doi: 10.1038/s41586-023-06950-4

PMCID:: PMC10881399

Abstract Article PDF–22M

Select item 107814933.

Investigating the ID3/SLC22A4 as immune-related signatures in ischemic stroke

Dading Lu, Heng Cai, Yugang Li, Wenyuan Chang, Xiu Liu, Qiwei Dai, Wanning Yu, Wangli Chen, Guomin Qiao, Haojie Xie, Xiong Xiao, Zhiqing Li

Aging (Albany NY) 2023 Dec 31; 15(24): 14803–14829. Published online 2023 Dec 14. doi: 10.18632/aging.205308

PMCID:: PMC10781493

Abstract Article PDF–2.4M

Select item 101768234.

A positive feedback loop between ID3 and PPARγ via DNA damage repair regulates the efficacy of radiotherapy for rectal cancer

Chuanzhong Huang, Ling Wang, Huijing Chen, Wankai Fu, Lingdong Shao, Dongmei Zhou, Junxin Wu, Yunbin Ye

BMC Cancer. 2023; 23: 429. Published online 2023 May 11. doi: 10.1186/s12885-023-10874-7

PMCID:: PMC10176823

Abstract Article PDF–13M

Select item 92759745.

Circadian Period 2 (Per2) downregulate inhibitor of differentiation 3 (Id3) expression via PTEN/AKT/Smad5 axis to inhibits glioma cell proliferation

Yifan Zhang, Xvlei Hu, Hailiang Li, Jian Yao, Ping Yang, Yuanxiang Lan, Hechun Xia

Bioengineered. 2022; 13(5): 12350–12364. Published online 2022 May 21. doi: 10.1080/21655979.2022.2074107

PMCID:: PMC9275974

Abstract Article PDF–14M

Select item 90188356.

Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription

Sang Bae Lee, Luciano Garofano, Aram Ko, Fulvio D’Angelo, Brulinda Frangaj, Danika Sommer, Qiwen Gan, KyeongJin Kim, Timothy Cardozo, Antonio Iavarone, Anna Lasorella

Nat Commun. 2022; 13: 2089. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29502-2

PMCID:: PMC9018835

Abstract Article PDF–2.1M

Select item 89231287.

Loss of ID3 in pancreatic cancer cells increases DNA damage without impairing MDC1 recruitment to the nuclear foci

Jian Xu, Mayrel Palestino Dominguez, Christine Alewine

Cancer Commun (Lond) 2022 Mar; 42(3): 269–272. Published online 2021 Dec 8. doi: 10.1002/cac2.12243

PMCID:: PMC8923128

Article PDF–774K

Select item 86410868.

ID1/ID3 mediate the contribution of skin fibroblasts to local nerve regeneration through Itga6 in wound repair

Zelin Chen, Gufang Shen, Xu Tan, Langfan Qu, Can Zhang, Le Ma, Peng Luo, Xiaohui Cao, Fan Yang, Yunsheng Liu, Yu Wang, Chunmeng Shi

Stem Cells Transl Med. 2021 Dec; 10(12): 1637–1649. Published online 2021 Sep 14. doi: 10.1002/sctm.21-0093

PMCID:: PMC8641086

Abstract Article PDF–21M

Select item 85998069.

ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition

Ali Bakr, Joschka Hey, Gianluca Sigismondo, Chun-Shan Liu, Ahmed Sadik, Ashish Goyal, Alice Cross, Ramya Lakshmana Iyer, Patrick Müller, Max Trauernicht, Kersten Breuer, Pavlo Lutsik, Christiane A Opitz, Jeroen Krijgsveld, Dieter Weichenhan, Christoph Plass, Odilia Popanda, Peter Schmezer

Nucleic Acids Res. 2021 Nov 18; 49(20): 11666–11689. Published online 2021 Oct 28. doi: 10.1093/nar/gkab964

Correction in:: Nucleic Acids Res. 2023 Nov 10; 51(20): 11407.

PMCID:: PMC8599806

Abstract Article PDF–7.2M

Select item 849948110.

EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression

Lanlan Fang, Yibo Gao, Zhen Wang, Yuxi Li, Yang Yan, Ze Wu, Jung-Chien Cheng, Ying-Pu Sun

Cell Commun Signal. 2021; 19: 101. Published online 2021 Oct 7. doi: 10.1186/s12964-021-00783-2

PMCID:: PMC8499481

Abstract Article PDF–5.6M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 770091012.

Role of inhibitor of differentiation 3 gene in cellular differentiation of human corneal stromal fibroblasts

Suneel Gupta, Lynn M. Martin, Nishant R. Sinha, Kaitlin E. Smith, Prashant R. Sinha, Emilee M. Dailey, Nathan P. Hesemann, Rajiv R. Mohan

Mol Vis. 2020; 26: 742–756. Published online 2020 Nov 25.

PMCID:: PMC7700910

Abstract Article PDF–6.4M

Select item 754388613.

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

Abhik K. Banerjee, Mario R. Blanco, Emily A. Bruce, Drew D. Honson, Linlin M. Chen, Amy Chow, Prashant Bhat, Noah Ollikainen, Sofia A. Quinodoz, Colin Loney, Jasmine Thai, Zachary D. Miller, Aaron E. Lin, Madaline M. Schmidt, Douglas G. Stewart, Daniel Goldfarb, Giuditta De Lorenzo, Suzannah J. Rihn, Rebecca M. Voorhees, Jason W. Botten, Devdoot Majumdar, Mitchell Guttman

Cell. 2020 Nov 25; 183(5): 1325–1339.e21. doi: 10.1016/j.cell.2020.10.004

PMCID:: PMC7543886

Abstract Article

Select item 737864514.

LEF1/Id3/HRAS axis promotes the tumorigenesis and progression of esophageal squamous cell carcinoma

Xinyu Wang, Yue Zhao, Xiang Fei, Qijue Lu, Yang Li, Yang Yuan, Chaojing Lu, Chunguang Li, Hezhong Chen

Int J Biol Sci. 2020; 16(13): 2392–2404. Published online 2020 Jun 29. doi: 10.7150/ijbs.47035

PMCID:: PMC7378645

Abstract Article PDF–3.7M

Select item 716998315.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 674264616.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3