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Items: 1 to 20 of 206

1.
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus
Mehmet Hakan Guney, Karthika Nagalekshmi, Sean Matthew McCauley, Claudia Carbone, Ozkan Aydemir, Jeremy Luban
Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29): e2404349121. Published online 2024 Jul 10. doi: 10.1073/pnas.2404349121
PMCID:
PMC11260138
AbstractArticlePDF–2.6M
2.
Polyinosinic‐polycytidylic acid liposome induces human hepatoma cells apoptosis which correlates to the up‐regulation of RIG‐I like receptors
Shuo Peng, Jianlin Geng, Rui Sun, Zhigang Tian, Haiming Wei
Cancer Sci. 2009 Mar; 100(3): 529–536. Published online 2008 Dec 22. doi: 10.1111/j.1349-7006.2008.01062.x
PMCID:
PMC11158103
AbstractArticlePDF–639K
3.
Genome-Wide Association Study Identifies IFIH1 and HLA-DQB1*05:02 Loci Associated With Anti-NMDAR Encephalitis
Xu Liu, Xiaodong Zheng, Yaqing Shu, Xiao Qu, Qun Wang, Xiao Liu, Fa-Yun Hu, Jie Liu, Yajun Lian, Bao-Ming He, Caihua Li, Dong Zhou, Wei Qiu, Liangdan Sun, Zhen Hong
Neurol Neuroimmunol Neuroinflamm. 2024 May; 11(3): e200221. Published online 2024 Apr 5. doi: 10.1212/NXI.0000000000200221
PMCID:
PMC11010247
AbstractArticlePDF–901K
4.
Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing
Rahul Singh, Yuan Wu, Alba Herrero del Valle, Kendra E. Leigh, Sai Mong, Mark T.K. Cheng, Brian J. Ferguson, Yorgo Modis
J Biol Chem. 2024 Mar; 300(3): 105711. Published online 2024 Feb 1. doi: 10.1016/j.jbc.2024.105711
PMCID:
PMC10909783
AbstractArticlePDF–8.3M
5.
Histone H1.2 Inhibited EMCV Replication through Enhancing MDA5-Mediated IFN-β Signaling Pathway
Yangran Song, Huixia Li, Ruiya Lian, Xueer Dou, Shasha Li, Jingying Xie, Xiangrong Li, Ruofei Feng, Zhiqiang Li
Viruses. 2024 Feb; 16(2): 174. Published online 2024 Jan 24. doi: 10.3390/v16020174
PMCID:
PMC10892618
AbstractArticlePDF–4.2M
6.
Anti-melanoma Differentiation-associated Gene 5 Antibody-positive Dermatomyositis Presenting as Refractory Gingivitis at the First Clinical Manifestation
Eiko Kawakami, Tomohisa Uchida, Naoki Iwamoto, Kazusato Hara, Kazuhiro Egashira, Atsushi Kawakami
Intern Med. 2024 Jan 1; 63(1): 131–134. Published online 2023 May 17. doi: 10.2169/internalmedicine.1621-23
PMCID:
PMC10824632
AbstractArticlePDF–1.1M
7.
Coxsackievirus A6 2C protein antagonizes IFN-β production through MDA5 and RIG-I depletion
Shao-Hua Wang, Juan Du, Jinghua Yu, Yifei Zhao, Yu Wang, Shucheng Hua, Ke Zhao
J Virol. 2023 Nov; 97(11): e01075-23. Published online 2023 Oct 17. doi: 10.1128/jvi.01075-23
PMCID:
PMC10688345
AbstractArticlePDF–14M
8.
SARS-CoV-2 Nsp8 suppresses MDA5 antiviral immune responses by impairing TRIM4-mediated K63-linked polyubiquitination
Xiaolin Zhang, Ziwei Yang, Ting Pan, Qinqin Sun, Qingyang Chen, Pei-Hui Wang, Xiaojuan Li, Ersheng Kuang
PLoS Pathog. 2023 Nov; 19(11): e1011792. Published online 2023 Nov 13. doi: 10.1371/journal.ppat.1011792
PMCID:
PMC10681309
AbstractArticlePDF–4.4M
9.
The IFIH1/MDA5 rs1990760 Gene Variant (946Thr) Differentiates Early- vs. Late-Onset Skin Disease and Increases the Risk of Arthritis in a Spanish Cohort of Psoriasis
Pablo Coto-Segura, Daniel Vázquez-Coto, Lucinda Velázquez-Cuervo, Claudia García-Lago, Eliecer Coto, Rubén Queiro
Int J Mol Sci. 2023 Oct; 24(19): 14803. Published online 2023 Sep 30. doi: 10.3390/ijms241914803
PMCID:
PMC10572774
AbstractArticlePDF–611K
10.
Predictors of rapidly progressive interstitial lung disease and prognosis in Chinese patients with anti-melanoma differentiation-associated gene 5-positive dermatomyositis
Meiqi Li, Xuli Zhao, Baocheng Liu, Yaqi Zhao, Xinya Li, Zhenzhen Ma, Qingrui Yang
Front Immunol. 2023; 14: 1209282. Published online 2023 Aug 24. doi: 10.3389/fimmu.2023.1209282
PMCID:
PMC10483132
AbstractArticlePDF–1.6M
11.
抗MDA5抗体阳性皮肌炎合并快速进展性间质性肺病的影响因素分析
媛媛 韩, 婷 姜, 泽昊 张, 玟 李, 云笛 江, 楚楚 陆, 宇 费, 波 陈
Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 Mar 20; 54(2): 422–425. Chinese. doi: 10.12182/20230360201
PMCID:
PMC10409163
AbstractArticlePDF–460K
12.
Association of the rs1990760, rs3747517, and rs10930046 polymorphisms in the IFIH1 gene with susceptibility to autoimmune diseases: a meta-analysis
Zilin Xiao, Shuoming Luo, Yuemin Zhou, Haipeng Pang, Wenfeng Yin, Jiabi Qin, Zhiguo Xie, Zhiguang Zhou
Front Immunol. 2023; 14: 1051247. Published online 2023 Jun 23. doi: 10.3389/fimmu.2023.1051247
PMCID:
PMC10327432
AbstractArticlePDF–1.3M
13.
FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia
Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen
J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0
PMCID:
PMC9922468
AbstractArticlePDF–4.9M
14.
Genetic variants of IFIH1 and DHX58 affect the chronicity of hepatitis C in the Chinese Han population
Peng Huang, Jing-Jing Wu, Jin-Wei Zhang, Yu-Qing Hou, Ping Zhu, Rong Yin, Rong-Bin Yu, Yun Zhang, Ming Yue, Wei Hou
PeerJ. 2023; 11: e14740. Published online 2023 Jan 30. doi: 10.7717/peerj.14740
PMCID:
PMC9893905
AbstractArticlePDF–9.6M
15.
Polymorphisms in ACE1, TMPRSS2, IFIH1, IFNAR2, and TYK2 Genes Are Associated with Worse Clinical Outcomes in COVID-19
Cristine Dieter, Leticia de Almeida Brondani, Natália Emerim Lemos, Ariell Freires Schaeffer, Caroline Zanotto, Denise Taurino Ramos, Eliandra Girardi, Felipe Mateus Pellenz, Joiza Lins Camargo, Karla Suzana Moresco, Lucas Lima da Silva, Mariana Rauback Aubin, Mayara Souza de Oliveira, Tatiana Helena Rech, Luís Henrique Canani, Fernando Gerchman, Cristiane Bauermann Leitão, Daisy Crispim
Genes (Basel) 2023 Jan; 14(1): 29. Published online 2022 Dec 22. doi: 10.3390/genes14010029
PMCID:
PMC9858252
AbstractArticlePDF–364K
16.
Chikungunya Virus nsP2 Impairs MDA5/RIG-I-Mediated Induction of NF-κB Promoter Activation: A Potential Target for Virus-Specific Therapeutics
Sojung Bae, Jeong Yoon Lee,, Jinjong Myoung
J Microbiol Biotechnol. 2020 Dec 28; 30(12): 1801–1809. Published online 2020 Dec 16. doi: 10.4014/jmb.2012.12005
PMCID:
PMC9728393
AbstractArticlePDF–2.0M
17.
Age-dependent effect of the IFIH1/MDA5 gene variants on the risk of critical COVID-19
María G. Muñiz-Banciella, Guillermo M. Albaiceta, Laura Amado-Rodríguez, Estefanía Salgado del Riego, Inés López Alonso, Cecilia López-Martínez, Paula Martín-Vicente, Marta García-Clemente, Tamara Hermida-Valverde, Ana I. Enríquez-Rodriguez, Cristina Hernández-González, Elías Cuesta-Llavona, Victoria Alvarez, Juan Gómez, Eliecer Coto
Immunogenetics. 2023; 75(2): 91–98. Published online 2022 Nov 25. doi: 10.1007/s00251-022-01281-6
PMCID:
PMC9702716
AbstractArticlePDF–834K
18.
Direct Interaction of Coronavirus Nonstructural Protein 3 with Melanoma Differentiation-Associated Gene 5 Modulates Type I Interferon Response during Coronavirus Infection
Xinxin Sun, Li Quan, Ruiai Chen, Dingxiang Liu
Int J Mol Sci. 2022 Oct; 23(19): 11692. Published online 2022 Oct 2. doi: 10.3390/ijms231911692
PMCID:
PMC9570369
AbstractArticlePDF–2.5M
19.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
20.
Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation
Yan-Ran Xu, Meng-Ling Shi, Yu Zhang, Na Kong, Cong Wang, Yi-Feng Xiao, Shi-Shen Du, Qi-Yun Zhu, Cao-Qi Lei
Proc Natl Acad Sci U S A. 2022 Jun 28; 119(26): e2122805119. Published online 2022 Jun 21. doi: 10.1073/pnas.2122805119
PMCID:
PMC9245648
AbstractArticlePDF–2.6M

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