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Items: 1 to 20 of 171

1.
Upregulation of FLIPS by Akt, a possible inhibition mechanism of TRAIL‐induced apoptosis in human gastric cancers
Seon Young Nam, Gyung‐Ah Jung, Gwong‐Cheung Hur, Hee‐Yong Chung, Woo Ho Kim, Dai‐Wu Seol, Byung Lan Lee
Cancer Sci. 2003 Dec; 94(12): 1066–1073. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01402.x
PMCID:
PMC11160312
AbstractArticlePDF–679K
2.
Knockdown of c‐FLIPL enhanced AD5‐10 anti‐death receptor 5 monoclonal antibody‐induced apoptosis in human lung cancer cells
Feng Chen, Juntang Guo, Yaxi Zhang, Yu Zhao, Naikang Zhou, Shilian Liu, Yanxin Liu, Dexian Zheng
Cancer Sci. 2009 May; 100(5): 940–947. Published online 2009 Feb 19. doi: 10.1111/j.1349-7006.2009.01119.x
Correction in:
Cancer Sci. 2009 Dec; 100(12): 2469.
PMCID:
PMC11158711
AbstractArticlePDF–2.1M
3.
Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis
Chao-Yu Yang, Chia-I Lien, Yi-Chun Tseng, Yi-Fan Tu, Arkadiusz W. Kulczyk, Yen-Chen Lu, Yin-Ting Wang, Tsung-Wei Su, Li-Chung Hsu, Yu-Chih Lo, Su-Chang Lin
Nat Commun. 2024; 15: 3791. Published online 2024 May 6. doi: 10.1038/s41467-024-47990-2
PMCID:
PMC11074299
AbstractArticlePDF–5.7M
4.
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis
Wen-ji Yang, Fang-hui Han, Yi-pei Gu, Hui Qu, Jia Liu, Jian-hua Shen, Ying Leng
Acta Pharmacol Sin. 2023 Aug; 44(8): 1649–1664. Published online 2023 Mar 30. doi: 10.1038/s41401-023-01081-y
PMCID:
PMC10374578
AbstractArticlePDF–23M
5.
Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1
Ruoshi Peng, Chris Kedong Wang, Xuan Wang‐Kan, Manja Idorn, Majken Kjær, Felix Y Zhou, Berthe Katrine Fiil, Frederik Timmermann, Susana L Orozco, Julia McCarthy, Carol S Leung, Xin Lu, Katrin Bagola, Jan Rehwinkel, Andrew Oberst, Jonathan Maelfait, Søren R Paludan, Mads Gyrd‐Hansen
EMBO Rep. 2022 Dec; 23(12): e55839. Published online 2022 Oct 21. doi: 10.15252/embr.202255839
PMCID:
PMC9724671
AbstractArticlePDF–1.8M
6.
c-FLIP promotes drug resistance in non-small-cell lung cancer cells via upregulating FoxM1 expression
Wen-die Wang, Yue Shang, Chen Wang, Jun Ni, Ai-min Wang, Gao-jie Li, Ling Su, Shu-zhen Chen
Acta Pharmacol Sin. 2022 Nov; 43(11): 2956–2966. Published online 2022 Apr 14. doi: 10.1038/s41401-022-00905-7
Correction in:
Acta Pharmacol Sin. 2024 Jul 23
PMCID:
PMC9622852
AbstractArticlePDF–4.0M
7.
CRISPR/Cas9 Screens Reveal Epstein-Barr Virus Transformed B-Cell Host Dependency Factors
Yijie Ma, Michael Walsh, Katharina Bernhardt, Camille W Ashbaugh, Stephen J Trudeau, Isabelle Ashbaugh, Sizun Jiang, Chang Jiang, Bo Zhao, David Root, John Doench, Benjamin E. Gewurz
Cell Host Microbe. Author manuscript; available in PMC 2022 Mar 22.
Published in final edited form as: Cell Host Microbe. 2017 May 10; 21(5): 580–591.e7. doi: 10.1016/j.chom.2017.04.005
PMCID:
PMC8938989
AbstractArticlePDF–2.0M
8.
The deubiquitinase Usp27x as a novel regulator of cFLIPL protein expression and sensitizer to death-receptor-induced apoptosis
Manuel Nico Dold, Xiulin Ng, Claudia Alber, Ian Edward Gentle, Georg Häcker, Arnim Weber
Apoptosis. 2022; 27(1-2): 112–132. Published online 2022 Jan 19. doi: 10.1007/s10495-021-01706-9
PMCID:
PMC8863773
AbstractArticlePDF–2.7M
9.
cFLIP downregulation is an early event required for endoplasmic reticulum stress-induced apoptosis in tumor cells
Rocío Mora-Molina, Daniela Stöhr, Markus Rehm, Abelardo López-Rivas
Cell Death Dis. 2022 Feb; 13(2): 111. Published online 2022 Feb 3. doi: 10.1038/s41419-022-04574-6
PMCID:
PMC8813907
AbstractArticlePDF–2.6M
10.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
11.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
12.
N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation
Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas
Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.
Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017
PMCID:
PMC8282764
AbstractArticlePDF–3.4M
13.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
14.
Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells
Jingru Huangfu, Caili Hao, Zongbo Wei, I. Michael Wormstone, Hong Yan, Xingjun Fan
Cell Death Dis. 2021 Apr; 12(4): 386. Published online 2021 Apr 9. doi: 10.1038/s41419-021-03683-y
PMCID:
PMC8035156
AbstractArticlePDF–6.8M
15.
MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL
Osamu Nakabayashi, Hirotaka Takahashi, Kenta Moriwaki, Sachiko Komazawa-Sakon, Fumiaki Ohtake, Shin Murai, Yuichi Tsuchiya, Yuki Koyahara, Yasushi Saeki, Yukiko Yoshida, Soh Yamazaki, Fuminori Tokunaga, Tatsuya Sawasaki, Hiroyasu Nakano
Commun Biol. 2021; 4: 80. Published online 2021 Jan 19. doi: 10.1038/s42003-020-01603-y
PMCID:
PMC7815719
AbstractArticlePDF–4.3M
16.
The SCFSkp2 ubiquitin ligase complex modulates TRAIL-R2-induced apoptosis by regulating FLIP(L)
Jamie Z. Roberts, Caitriona Holohan, Tamas Sessler, Jennifer Fox, Nyree Crawford, Joel S. Riley, Hajrah Khawaja, Joanna Majkut, Emma Evergren, Luke M. Humphreys, Jennifer Ferris, Catherine Higgins, Margarita Espona-Fiedler, Paul Moynagh, Simon S. McDade, Daniel B. Longley
Cell Death Differ. 2020 Sep; 27(9): 2726–2741. Published online 2020 Apr 20. doi: 10.1038/s41418-020-0539-7
PMCID:
PMC7429845
AbstractArticlePDF–4.6M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
Efficient recruitment of c‐FLIPL to the death‐inducing signaling complex leads to Fas resistance in natural killer‐cell lymphoma
Azuchi Masuda, Yasushi Isobe, Koichi Sugimoto, Mayumi Yoshimori, Ayako Arai, Norio Komatsu
Cancer Sci. 2020 Mar; 111(3): 807–816. Published online 2020 Jan 31. doi: 10.1111/cas.14296
PMCID:
PMC7060462
AbstractArticlePDF–1.6M
19.
Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation
Seon Min Woo, Seung Un Seo, Peter Kubatka, Kyoung-jin Min, Taeg Kyu Kwon
Biomolecules. 2019 Dec; 9(12): 838. Published online 2019 Dec 6. doi: 10.3390/biom9120838
PMCID:
PMC6995549
AbstractArticlePDF–3.3M
20.
Superoxide induced inhibition of death receptor signaling is mediated via induced expression of apoptosis inhibitory protein cFLIP
Jayshree L. Hirpara, Kothandharaman Subramaniam, Gregory Bellot, Jianhua Qu, Serena Seah, Thomas Loh, Lisa Tucker-Kellogg, Marie-Veronique Clement, Shazib Pervaiz
Redox Biol. 2020 Feb; 30: 101403. Published online 2019 Dec 16. doi: 10.1016/j.redox.2019.101403
PMCID:
PMC6965745
AbstractArticlePDF–2.8M

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