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Items: 1 to 20 of 33

1.
Expression of the phagocytic receptors αMβ2 and αXβ2 is controlled by RIAM, VASP and Vinculin in neutrophil-differentiated HL-60 cells
Alvaro Torres-Gomez, Tara Fiyouzi, Claudia Guerra-Espinosa, Beatriz Cardeñes, Irene Clares, Víctor Toribio, Pedro A. Reche, Carlos Cabañas, Esther M. Lafuente
Front Immunol. 2022; 13: 951280. Published online 2022 Sep 27. doi: 10.3389/fimmu.2022.951280
PMCID:
PMC9552961
AbstractArticlePDF–8.6M
2.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
3.
Structural, biochemical, and functional properties of the Rap1-Interacting Adaptor Molecule (RIAM)
Duygu Sari-Ak, Alvaro Torres-Gomez, Yavuz-Furkan Yazicioglu, Anthos Christofides, Nikolaos Patsoukis, Esther M. Lafuente, Vassiliki A. Boussiotis
Biomed J. 2022 Apr; 45(2): 289–298. Published online 2021 Oct 1. doi: 10.1016/j.bj.2021.09.005
PMCID:
PMC9250098
AbstractArticlePDF–1.2M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Phosphorylation of RIAM by Src Promotes Integrin Activation by Unmasking the PH domain of RIAM
Eun-Ah Cho, Pingfeng Zhang, Vikas Kumar, Mikhail Kavalchuk, Hao Zhang, Qingqiu Huang, James S Duncan, Jinhua Wu
Structure. Author manuscript; available in PMC 2022 Apr 1.
Published in final edited form as: Structure. 2021 Apr 1; 29(4): 320–329.e4. Published online 2020 Dec 3. doi: 10.1016/j.str.2020.11.011
PMCID:
PMC8026550
AbstractArticlePDF–2.1M
6.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
7.
Talin dissociates from RIAM and associates to vinculin sequentially in response to the actomyosin force
Clémence Vigouroux, Véronique Henriot, Christophe Le Clainche
Nat Commun. 2020; 11: 3116. Published online 2020 Jun 19. doi: 10.1038/s41467-020-16922-1
PMCID:
PMC7305319
AbstractArticlePDF–3.5M
8.
RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment
Alvaro Torres-Gomez, Jose Luis Sanchez-Trincado, Víctor Toribio, Raul Torres-Ruiz, Sandra Rodríguez-Perales, María Yáñez-Mó, Pedro A. Reche, Carlos Cabañas, Esther M. Lafuente
Cells. 2020 May; 9(5): 1166. Published online 2020 May 8. doi: 10.3390/cells9051166
PMCID:
PMC7291270
AbstractArticlePDF–3.3M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation
Yu-Chung Chang, Wenjuan Su, Eun-ah Cho, Hao Zhang, Qingqiu Huang, Mark R. Philips, Jinhua Wu
Proc Natl Acad Sci U S A. 2019 Feb 26; 116(9): 3524–3529. Published online 2019 Feb 7. doi: 10.1073/pnas.1818880116
PMCID:
PMC6397589
AbstractArticlePDF–1.2M
11.
WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation
Woo-Jeong Jeong, Jong-Chan Park, Woo-Shin Kim, Eun Ji Ro, Soung Hoo Jeon, Sang-Kyu Lee, Young Nyun Park, Do Sik Min, Kang-Yell Choi
Nat Commun. 2019; 10: 295. Published online 2019 Jan 17. doi: 10.1038/s41467-018-08230-6
PMCID:
PMC6336889
AbstractArticlePDF–2.9M
12.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
13.
RIAM (Rap1-interacting adaptor molecule) regulates complement-dependent phagocytosis
Iria Medraño-Fernandez, Raquel Reyes, Isabel Olazabal, Elena Rodriguez, Francisco Sanchez-Madrid, Vassiliki A. Boussiotis, Pedro A. Reche, Carlos Cabañas, Esther M. Lafuente
Cell Mol Life Sci. 2013 Jul; 70(13): 2395–2410. Published online 2013 Feb 19. doi: 10.1007/s00018-013-1268-6
PMCID:
PMC5474120
AbstractArticlePDF–1.3M
14.
The Rap1-RIAM-talin axis of integrin activation and blood cell function
Frederic Lagarrigue, Chungho Kim, Mark H. Ginsberg
Blood. 2016 Jul 28; 128(4): 479–487. Prepublished online 2016 May 20. doi: 10.1182/blood-2015-12-638700
PMCID:
PMC4965904
AbstractArticle
15.
Widespread expansion of protein interaction capabilities by alternative splicing
Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal
Cell. Author manuscript; available in PMC 2017 Feb 11.
Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029
PMCID:
PMC4882190
AbstractArticlePDF–1.9M
16.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
17.
A RIAM/lamellipodin–talin–integrin complex forms the tip of sticky fingers that guide cell migration
Frederic Lagarrigue, Praju Vikas Anekal, Ho-Sup Lee, Alexia I. Bachir, Jailal N. Ablack, Alan F. Horwitz, Mark H. Ginsberg
Nat Commun. 2015; 6: 8492. Published online 2015 Sep 30. doi: 10.1038/ncomms9492
PMCID:
PMC4589889
AbstractArticlePDF–2.8M
18.
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease
Stefanie L. Butland, Shaun S. Sanders, Mandi E. Schmidt, Sean-Patrick Riechers, David T.S. Lin, Dale D.O. Martin, Kuljeet Vaid, Rona K. Graham, Roshni R. Singaraja, Erich E. Wanker, Elizabeth Conibear, Michael R. Hayden
Hum Mol Genet. 2014 Aug 1; 23(15): 4142–4160. Published online 2014 Apr 4. doi: 10.1093/hmg/ddu137
PMCID:
PMC4082372
AbstractArticlePDF–1.7M
19.
Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism
Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva
Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650
Correction in:
Nat Commun. 2023; 14: 569.
PMCID:
PMC3996537
AbstractArticlePDF–1.9M
20.
GENOMIC ASSOCIATION ANALYSIS IDENTIFIES MULTIPLE LOCI INFLUENCING ANTIHYPERTENSIVE RESPONSE TO AN ANGIOTENSIN II RECEPTOR BLOCKER
Stephen T. Turner, Kent R. Bailey, Gary L. Schwartz, Arlene B. Chapman, High Seng Chai, Eric Boerwinkle
Hypertension. Author manuscript; available in PMC 2013 Jun 1.
Published in final edited form as: Hypertension. 2012 Jun; 59(6): 1204–1211. Published online 2012 May 7. doi: 10.1161/HYP.0b013e31825b30f8
PMCID:
PMC3530397
AbstractArticlePDF–1.3M

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