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Items: 1 to 20 of 56

1.
MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells
Signe Meng, Ester E. Sørensen, Muthulakshmi Ponniah, Jeppe Thorlacius-Ussing, Roxane Crouigneau, Tanja Larsen, Magnus T. Borre, Nicholas Willumsen, Mette Flinck, Stine F. Pedersen
J Cell Sci. 2024 Apr 15; 137(8): jcs261608. Published online 2024 Apr 30. doi: 10.1242/jcs.261608
PMCID:
PMC11112124
AbstractArticle
2.
Homology modeling and site-directed mutagenesis identify amino acid residues underlying the substrate selection mechanism of human monocarboxylate transporters 1 (hMCT1) and 4 (hMCT4)
Yuya Futagi, Masaki Kobayashi, Katsuya Narumi, Ayako Furugen, Ken Iseki
Cell Mol Life Sci. 2019 Dec; 76(24): 4905–4921. Published online 2019 May 17. doi: 10.1007/s00018-019-03151-z
PMCID:
PMC11105385
AbstractArticlePDF–8.2M
3.
SYVN1-mediated ubiquitylation directs localization of MCT4 in the plasma membrane to promote the progression of lung adenocarcinoma
Meng Zhao, Chen Huang, Lexin Yang, Boyu Pan, Shuting Yang, Jiao Chang, Yu Jin, Gang Zhao, Dongsheng Yue, Shuo Qie, Li Ren
Cell Death Dis. 2023 Oct; 14(10): 666. Published online 2023 Oct 10. doi: 10.1038/s41419-023-06208-x
PMCID:
PMC10564934
AbstractArticlePDF–6.4M
4.
GLUT1, LDHA, and MCT4 Expression Is Deregulated in Cervical Cancer and Precursor Lesions
Ma. A. Reyna-Hernández, Luz del C. Alarcón-Romero, Julio Ortiz-Ortiz, Berenice Illades-Aguiar, Marco A. Jiménez-López, Azucena Ocampo-Bárcenas, Martin O. Morrugares-Ixtepan, Francisco I. Torres-Rojas
J Histochem Cytochem. 2022 Jun; 70(6): 437–446. Published online 2022 May 26. doi: 10.1369/00221554221101662
PMCID:
PMC9169107
AbstractArticlePDF–1.1M
5.
TRIM72 exerts antitumor effects in breast cancer and modulates lactate production and MCT4 promoter activity by interacting with PPP3CA
Zheng Wang, Haixia Li, Hongxia Wang, Xin Li, Qiong Zhang, Haifang Wang, Kui Li, Yurong Qiu
Anticancer Drugs. 2022 Jun; 33(5): 489–501. Published online 2022 Mar 23. doi: 10.1097/CAD.0000000000001304
PMCID:
PMC8997701
AbstractArticlePDF–1.4M
6.
Comprehensive Analysis of Monocarboxylate Transporter 4 (MCT4) expression in breast cancer prognosis and immune infiltration via integrated bioinformatics analysis
Chen Yuan, Jie Zhang, Jianjuan Lou, Siqi Wang, Yanni Jiang, Feiyun Wu, Shouju Wang
Bioengineered. 2021; 12(1): 3850–3863. Published online 2021 Jul 16. doi: 10.1080/21655979.2021.1951928
PMCID:
PMC8806482
AbstractArticlePDF–3.0M
7.
miR-31-NUMB Cascade Modulates Monocarboxylate Transporters to Increase Oncogenicity and Lactate Production of Oral Carcinoma Cells
Chung-Hsien Chou, Chun-Yu Fan Chiang, Cheng-Chieh Yang, Ying-Chieh Liu, Sih-Rou Chang, Kuo-Wei Chang, Shu-Chun Lin
Int J Mol Sci. 2021 Nov; 22(21): 11731. Published online 2021 Oct 29. doi: 10.3390/ijms222111731
PMCID:
PMC8584161
AbstractArticlePDF–3.0M
8.
MCT4 is induced by metastasis-enhancing pathogenic mitochondrial NADH dehydrogenase gene mutations and can be a therapeutic target
Keizo Takenaga, Nobuko Koshikawa, Miho Akimoto, Yasutoshi Tatsumi, Jason Lin, Makiko Itami, Hiroki Nagase
Sci Rep. 2021; 11: 13302. Published online 2021 Jun 25. doi: 10.1038/s41598-021-92772-1
PMCID:
PMC8233425
AbstractArticlePDF–8.2M
9.
Monocarboxylate Transporter 4 Triggered Cell Pyroptosis to Aggravate Intestinal Inflammation in Inflammatory Bowel Disease
Yaodong Wang, Xiaorong Zhou, Kejian Zou, Guanhua Chen, Ling Huang, Fangying Yang, Wenxu Pan, Hongwei Xu, Zhaohui Xu, Huan Chen, Jiayu Chen, Sitang Gong, Xuan Zhou, Wanfu Xu, Junhong Zhao
Front Immunol. 2021; 12: 644862. Published online 2021 May 19. doi: 10.3389/fimmu.2021.644862
PMCID:
PMC8170300
AbstractArticlePDF–7.6M
10.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
11.
Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report)
Irene Dell’Anno, Elisa Barone, Luciano Mutti, Doris M. Rassl, Stefan J. Marciniak, Roberto Silvestri, Stefano Landi, Federica Gemignani
J Transl Med. 2020; 18: 341. Published online 2020 Sep 4. doi: 10.1186/s12967-020-02487-6
PMCID:
PMC7650278
AbstractArticlePDF–1.2M
12.
Intratumoral Distribution of Lactate and the Monocarboxylate Transporters 1 and 4 in Human Glioblastoma Multiforme and Their Relationships to Tumor Progression-Associated Markers
Carolin Kubelt, Sönke Peters, Hajrullah Ahmeti, Monika Huhndorf, Lukas Huber, Gesa Cohrs, Jan-Bernd Hövener, Olav Jansen, Michael Synowitz, Janka Held-Feindt
Int J Mol Sci. 2020 Sep; 21(17): 6254. Published online 2020 Aug 29. doi: 10.3390/ijms21176254
PMCID:
PMC7504270
AbstractArticlePDF–3.6M
13.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
14.
Monocarboxylate transporters in cancer
Valéry L. Payen, Erica Mina, Vincent F. Van Hée, Paolo E. Porporato, Pierre Sonveaux
Mol Metab. 2020 Mar; 33: 48–66. Published online 2019 Jul 27. doi: 10.1016/j.molmet.2019.07.006
PMCID:
PMC7056923
AbstractArticlePDF–1.6M
15.
Intratumoral reciprocal expression of monocarboxylate transporter 4 and glypican-3 in hepatocellular carcinomas
Kenji Yorita, Akinobu Ohno, Takahiro Nishida, Kazuhiro Kondo, Toshihiko Ohtomo, Hiroaki Kataoka
BMC Res Notes. 2019; 12: 741. Published online 2019 Nov 9. doi: 10.1186/s13104-019-4778-y
PMCID:
PMC6842510
AbstractArticlePDF–1.5M
16.
Cigarette Smoke Induces Metabolic Reprogramming of the Tumor Stroma in Head and Neck Squamous Cell Carcinoma
Marina Domingo-Vidal, Diana Whitaker-Menezes, Cristina Martos-Rus, Patrick Tassone, Christopher M. Snyder, Madalina Tuluc, Nancy Philp, Joseph Curry, Ubaldo Martinez-Outschoorn
Mol Cancer Res. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Mol Cancer Res. 2019 Sep; 17(9): 1893–1909. Published online 2019 Jun 25. doi: 10.1158/1541-7786.MCR-18-1191
PMCID:
PMC6726526
AbstractArticlePDF–2.5M
17.
Monocarboxylate Transporter 4 (MCT4) Overexpression Is Correlated with Poor Prognosis of Osteosarcoma
Yannan Liu, Xuanwu Sun, Chunguang Huo, Chu Sun, Jianfeng Zhu
Med Sci Monit. 2019; 25: 4278–4284. Published online 2019 Jun 9. doi: 10.12659/MSM.912272
PMCID:
PMC6582689
AbstractArticlePDF–1.6M
18.
Aberrant MCT4 and GLUT1 expression is correlated with early recurrence and poor prognosis of hepatocellular carcinoma after hepatectomy
Hai‐Long Chen, Han‐Yue OuYang, Yong Le, Peng Jiang, Hui Tang, Zi‐Shan Yu, Min‐Ke He, Yun‐Qiang Tang, Ming Shi
Cancer Med. 2018 Nov; 7(11): 5339–5350. Published online 2018 Oct 10. doi: 10.1002/cam4.1521
PMCID:
PMC6246944
AbstractArticlePDF–846K
19.
Mitochondrial and glycolytic metabolic compartmentalization in Diffuse Large B Cell Lymphoma
Mahasweta Gooptu, Diana Whitaker-Menezes, John Sprandio, Marina Domingo-Vidal, Zhao Lin, Guldeep Uppal, Jerald Gong, Roberto Fratamico, Benjamin Leiby, Alina Dulau-Florea, Jaime Caro, Ubaldo Martinez-Outschoorn
Semin Oncol. Author manuscript; available in PMC 2018 Oct 10.
Published in final edited form as: Semin Oncol. 2017 Jun; 44(3): 204–217. Published online 2017 Oct 10. doi: 10.1053/j.seminoncol.2017.10.002
PMCID:
PMC5737785
AbstractArticlePDF–1.6M
20.
Hodgkin Lymphoma: A Complex Metabolic Ecosystem with Glycolytic Reprogramming of the Tumor Microenvironment
Lekha Mikkilineni, Diana Whitaker-Menezes, Marina Domingo-Vidal, John Sprandio, Paola Avena, Paolo Cotzia, Alina Dulau-Florea, Jerald Gong, Guldeep Uppal, Tingting Zhan, Benjamin Leiby, Zhao Lin, Barbara Pro, Federica Sotgia, Michael P. Lisanti, Ubaldo Martinez-Outschoorn
Semin Oncol. Author manuscript; available in PMC 2018 Oct 10.
Published in final edited form as: Semin Oncol. 2017 Jun; 44(3): 218–225. Published online 2017 Oct 10. doi: 10.1053/j.seminoncol.2017.10.003
PMCID:
PMC5737784
AbstractArticlePDF–954K

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